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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lfqA28Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lfqA28Cyclin-dependent kinase 22.7.11.221.000
3lfnA27Cyclin-dependent kinase 22.7.11.220.583
3lfsA07Cyclin-dependent kinase 22.7.11.220.582
3le62BZCyclin-dependent kinase 22.7.11.220.549
4fki09KCyclin-dependent kinase 22.7.11.220.522
1oirHDYCyclin-dependent kinase 22.7.11.220.512
4fklCK2Cyclin-dependent kinase 22.7.11.220.503
3r83Z14Cyclin-dependent kinase 22.7.11.220.498
2ds11CDCyclin-dependent kinase 22.7.11.220.495
1aq1STUCyclin-dependent kinase 22.7.11.220.494
2b53D23Cyclin-dependent kinase 22.7.11.220.494
2w05FRTCyclin-dependent kinase 22.7.11.220.494
2r3jSCJCyclin-dependent kinase 22.7.11.220.490
2c6o4SPCyclin-dependent kinase 22.7.11.220.488
1w8cN69Cyclin-dependent kinase 22.7.11.220.484
3r8lZ30Cyclin-dependent kinase 22.7.11.220.482
4ek816KCyclin-dependent kinase 22.7.11.220.482
4ek610KCyclin-dependent kinase 22.7.11.220.479
4fkt48KCyclin-dependent kinase 22.7.11.220.473
2btrU73Cyclin-dependent kinase 22.7.11.220.472
2a4lRRCCyclin-dependent kinase 22.7.11.220.471
3r1yX76Cyclin-dependent kinase 22.7.11.220.470
3r7yZ04Cyclin-dependent kinase 22.7.11.220.463
1pxoCK7Cyclin-dependent kinase 22.7.11.220.462
1ykr628Cyclin-dependent kinase 22.7.11.220.461
2vtrLZBCyclin-dependent kinase 22.7.11.220.461
2a0cCK9Cyclin-dependent kinase 22.7.11.220.460
2uznC96Cyclin-dependent kinase 22.7.11.220.460
3qwjX6ACyclin-dependent kinase 22.7.11.220.459
1oitHDTCyclin-dependent kinase 22.7.11.220.457
2c5yMTWCyclin-dependent kinase 22.7.11.220.457
3qqlX03Cyclin-dependent kinase 22.7.11.220.457
4fkv61KCyclin-dependent kinase 22.7.11.220.457
4fkg4CKCyclin-dependent kinase 22.7.11.220.455
2w1hL0FCyclin-dependent kinase 22.7.11.220.452
3qxpX64Cyclin-dependent kinase 22.7.11.220.452
3rni21ZCyclin-dependent kinase 22.7.11.220.452
1b38ATPCyclin-dependent kinase 22.7.11.220.451
4erwSTUCyclin-dependent kinase 22.7.11.220.450
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.449
1pxlCK4Cyclin-dependent kinase 22.7.11.220.447
1y91CT9Cyclin-dependent kinase 22.7.11.220.446
3rkb12ZCyclin-dependent kinase 22.7.11.220.445
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.441
2bheBRYCyclin-dependent kinase 22.7.11.220.440
3r8vZ62Cyclin-dependent kinase 22.7.11.220.440