sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ldw	ZOL	Farnesyl pyrophosphate synthase, putative

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3ldw	ZOL	Farnesyl pyrophosphate synthase, putative	/	1.000
3ldw	IPE	Farnesyl pyrophosphate synthase, putative	/	0.813
3ez3	IPE	Farnesyl pyrophosphate synthase, putative	/	0.563
4nke	RIS	Farnesyl pyrophosphate synthase	2.5.1.10	0.529
4q23	RIS	Farnesyl pyrophosphate synthase	2.5.1.10	0.505
3ez3	ZOL	Farnesyl pyrophosphate synthase, putative	/	0.487
3rbm	B73	Farnesyl pyrophosphate synthase, putative	/	0.474
4lfv	YS4	Farnesyl pyrophosphate synthase	2.5.1.10	0.465
3ryw	K9H	Farnesyl pyrophosphate synthase, putative	/	0.457
2opm	NI9	Farnesyl pyrophosphate synthase	2.5.1.10	0.455