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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3l8xN4DMitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3l8xN4DMitogen-activated protein kinase 14/1.000
2zb0GK3Mitogen-activated protein kinase 14/0.621
3s4qNK0Mitogen-activated protein kinase 14/0.617
3iphG11Mitogen-activated protein kinase 14/0.614
3gfeP37Mitogen-activated protein kinase 14/0.612
2rg6287Mitogen-activated protein kinase 14/0.611
1zyjBI5Mitogen-activated protein kinase 14/0.600
3fklFKLMitogen-activated protein kinase 14/0.599
2rg5279Mitogen-activated protein kinase 14/0.594
4kip1R9Mitogen-activated protein kinase 14/0.590
3mpt1GKMitogen-activated protein kinase 14/0.583
4eh60ONMitogen-activated protein kinase 14/0.582
3fln3FNMitogen-activated protein kinase 14/0.581
3mvl38PMitogen-activated protein kinase 14/0.581
4aa5NQBMitogen-activated protein kinase 14/0.580
3ocgOCGMitogen-activated protein kinase 14/0.579
4kin1M8Mitogen-activated protein kinase 14/0.578
2balPQAMitogen-activated protein kinase 14/0.577
3uvp048Mitogen-activated protein kinase 14/0.577
3roc29AMitogen-activated protein kinase 14/0.575
3hllI45Mitogen-activated protein kinase 14/0.574
3gc9B45Mitogen-activated protein kinase 112.7.11.240.566
2zb1GK4Mitogen-activated protein kinase 14/0.565
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.564
3dt1P40Mitogen-activated protein kinase 14/0.563
4kiq1RAMitogen-activated protein kinase 14/0.556
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.555
3itzP66Mitogen-activated protein kinase 14/0.554
3flzFLZMitogen-activated protein kinase 14/0.552
3fmh533Mitogen-activated protein kinase 14/0.552
3fi4FI4Mitogen-activated protein kinase 14/0.550
3flyFLYMitogen-activated protein kinase 14/0.550
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.550
3bv2P38Mitogen-activated protein kinase 14/0.549
3nww3NWMitogen-activated protein kinase 14/0.549
2qd9LGFMitogen-activated protein kinase 14/0.548
3u8w09JMitogen-activated protein kinase 14/0.547
3fmkFMKMitogen-activated protein kinase 14/0.546
3hp552PMitogen-activated protein kinase 14/0.545
3bv3P39Mitogen-activated protein kinase 14/0.544
3mpaSB2Mitogen-activated protein kinase 14/0.543
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.542
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.541
3hl7I47Mitogen-activated protein kinase 14/0.540
3mvm39PMitogen-activated protein kinase 14/0.540
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.538
4aa4QC0Mitogen-activated protein kinase 14/0.537
2gfsPQBMitogen-activated protein kinase 14/0.535
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.534
3uvqFS8Mitogen-activated protein kinase 14/0.534
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.531
1ywrLI9Mitogen-activated protein kinase 14/0.530
4lopSB4Mitogen-activated protein kinase 14/0.530
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.528
1ouy094Mitogen-activated protein kinase 14/0.527
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.527
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.526
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.525
3fmn530Mitogen-activated protein kinase 14/0.525
5f0a1FBcGMP-dependent protein kinase, putative/0.525
2of4979Tyrosine-protein kinase Lck2.7.10.20.524
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.524
3flsFLSMitogen-activated protein kinase 14/0.522
3fsfFSSMitogen-activated protein kinase 14/0.521
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.521
3uibSB2Putative mitogen-activated protein kinase/0.521
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.520
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.519
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.518
3flwFLWMitogen-activated protein kinase 14/0.518
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.518
3fskRO6Mitogen-activated protein kinase 14/0.517
2of2547Tyrosine-protein kinase Lck2.7.10.20.516
3lfa1N1Mitogen-activated protein kinase 14/0.515
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.515
1di9MSQMitogen-activated protein kinase 14/0.514
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.514
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.514
4nk92K5Fibroblast growth factor receptor 1/0.514
1m7qDQOMitogen-activated protein kinase 14/0.513
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.513
4f630S7Fibroblast growth factor receptor 1/0.513
3bx5304Mitogen-activated protein kinase 14/0.512
1zz2B11Mitogen-activated protein kinase 14/0.511
4nka2K7Fibroblast growth factor receptor 1/0.511
3vjoANPEpidermal growth factor receptor2.7.10.10.510
4y93746Tyrosine-protein kinase/0.510
2vwx7X4Ephrin type-B receptor 42.7.10.10.509
3o8tBMUMitogen-activated protein kinase 14/0.508
4gk2L66Ephrin type-A receptor 32.7.10.10.508
2y6o1N1Ephrin type-A receptor 42.7.10.10.507
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.507
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.507
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.506
3vs3VSETyrosine-protein kinase HCK2.7.10.20.505
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.504
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.503
3fl4FL4Mitogen-activated protein kinase 14/0.503
3ac2KSETyrosine-protein kinase Lck2.7.10.20.502
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.502
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.501
1ouk084Mitogen-activated protein kinase 14/0.500
2fgiPD1Fibroblast growth factor receptor 1/0.499
2pv7NADT-protein1.3.1.120.499
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.499
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.499
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.499
1xkkFMMEpidermal growth factor receptor2.7.10.10.498
3fc152PMitogen-activated protein kinase 14/0.498
2hk51BMTyrosine-protein kinase HCK2.7.10.20.497
1w7h3IPMitogen-activated protein kinase 14/0.496
4jq8KJ8Epidermal growth factor receptor2.7.10.10.496
4nks2M2Fibroblast growth factor receptor 1/0.496
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.495
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.495
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.495
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.495
4yuqKS1Calmodulin-like domain protein kinase/0.495
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.494
1yw2PGJMitogen-activated protein kinase 14/0.494
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.494
4looSB4Mitogen-activated protein kinase 14/0.494
5e8wSTUTGF-beta receptor type-12.7.11.300.494
3vryB43Tyrosine-protein kinase HCK2.7.10.20.493
4eh70OOMitogen-activated protein kinase 14/0.492
4jq7KJQEpidermal growth factor receptor2.7.10.10.492
1m17AQ4Epidermal growth factor receptor2.7.10.10.491
3fmmXI2Mitogen-activated protein kinase 14/0.491
3nbwTR4Ketohexokinase/0.491
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.491
4nfn2KCTau-tubulin kinase 12.7.11.10.491
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.490
3ac1KZITyrosine-protein kinase Lck2.7.10.20.490
3fkoFKOMitogen-activated protein kinase 14/0.490
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.489
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.489
2zazGK1Mitogen-activated protein kinase 14/0.489
2ghmLICMitogen-activated protein kinase 14/0.488
3ha85JZMitogen-activated protein kinase 14/0.488
4j97ACPFibroblast growth factor receptor 2/0.488
3d7zGK5Mitogen-activated protein kinase 14/0.487
4hyu1BKMitogen-activated protein kinase 82.7.11.240.487
2gs7ANPEpidermal growth factor receptor2.7.10.10.486
2vx07X7Ephrin type-B receptor 42.7.10.10.486
3ns2PYVAbscisic acid receptor PYL2/0.486
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.486
3rinI2OMitogen-activated protein kinase 14/0.485
4eym0RXMitogen-activated protein kinase 132.7.11.240.485
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.485
2itzIREEpidermal growth factor receptor2.7.10.10.484
2og81N8Tyrosine-protein kinase Lck2.7.10.20.484
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.484
3w33W19Epidermal growth factor receptor2.7.10.10.484
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.484
5iubCLRAdenosine receptor A2a/0.484
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.483
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.483
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.483
4fnzNZFALK tyrosine kinase receptor2.7.10.10.483
1phgMYTCamphor 5-monooxygenase1.14.15.10.482
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.482
4f640S8Fibroblast growth factor receptor 1/0.482
4jr3KJREpidermal growth factor receptor2.7.10.10.482
1zzlTZYMitogen-activated protein kinase 14/0.481
3e92G6AMitogen-activated protein kinase 14/0.481
3gcq1BUMitogen-activated protein kinase 14/0.481
4eh3NARMitogen-activated protein kinase 14/0.481
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.481
4othDRNSerine/threonine-protein kinase N1/0.481
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.480
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.480
3fknFKNMitogen-activated protein kinase 14/0.480
4anqVGHALK tyrosine kinase receptor2.7.10.10.480
5k2dZMAAdenosine receptor A2a/0.480
1agwSU2Fibroblast growth factor receptor 1/0.479
2jedLG8Protein kinase C theta type2.7.11.130.479
3gc7B45Mitogen-activated protein kinase 14/0.479
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.479
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.479
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.478
3gubGUBDeath-associated protein kinase 12.7.11.10.478
4dlj6RGMitogen-activated protein kinase 14/0.478
5k2cZMAAdenosine receptor A2a/0.478
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
2itxANPEpidermal growth factor receptor2.7.10.10.477
2qocANPEphrin type-A receptor 32.7.10.10.477
3ds6A17Mitogen-activated protein kinase 14/0.477
3f03FMNPentaerythritol tetranitrate reductase/0.477
3iw5DF3Mitogen-activated protein kinase 14/0.477
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.477
4hjoAQ4Epidermal growth factor receptor2.7.10.10.477
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.477
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3iw6PP0Mitogen-activated protein kinase 14/0.476
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.476
1scuCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.475
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.475
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.475
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.475
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.475
3fpjSAMUncharacterized protein/0.475
3lshFADPyranose 2-oxidase/0.475
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.475
4hys1BJMitogen-activated protein kinase 82.7.11.240.475
1ie4T44Transthyretin/0.474
1qvnFRIInterleukin-2/0.474
3nr4PYVAbscisic acid receptor PYL2/0.474
3t2zFADSulfide-quinone reductase/0.474
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.474
4izy1J2Mitogen-activated protein kinase 82.7.11.240.474
5ax35IDMitogen-activated protein kinase 12.7.11.240.474
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.473
2baqPQBMitogen-activated protein kinase 14/0.473
2itnANPEpidermal growth factor receptor2.7.10.10.473
3a1nNADNDP-sugar epimerase/0.473
5e8xSTUTGF-beta receptor type-12.7.11.300.473
2vd5BI8Myotonin-protein kinase2.7.11.10.472
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.472
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.472
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.472
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.472
1jpaANPEphrin type-B receptor 22.7.10.10.471
1o76CAMCamphor 5-monooxygenase1.14.15.10.471
2vwz7X6Ephrin type-B receptor 42.7.10.10.471
3acjKSSTyrosine-protein kinase Lck2.7.10.20.471
3hvcGG5Mitogen-activated protein kinase 14/0.471
3hx4ANPCalmodulin-domain protein kinase 1/0.471
3iw7IPKMitogen-activated protein kinase 14/0.471
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.471
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.471
4wboANWRhodopsin kinase/0.471
1bveDMPGag-Pol polyprotein3.4.23.160.470
1iwjCAMCamphor 5-monooxygenase1.14.15.10.470
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.470
2itwITQEpidermal growth factor receptor2.7.10.10.470
2v52LABActin, alpha skeletal muscle/0.470
2vwy7X5Ephrin type-B receptor 42.7.10.10.470
3f47I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.470
3kf7L9GMitogen-activated protein kinase 14/0.470
3l8sBFFMitogen-activated protein kinase 14/0.470
3sz0FADSulfide-quinone reductase/0.470
3w2o03PEpidermal growth factor receptor2.7.10.10.470
4ih8B43Calmodulin-domain protein kinase 1/0.470
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.470
1ove358Mitogen-activated protein kinase 14/0.469
2itpAEEEpidermal growth factor receptor2.7.10.10.469
2vv9IM9Cyclin-dependent kinase 22.7.11.220.469
2xyuQ9GEphrin type-A receptor 42.7.10.10.469
2zybKSLTyrosine-protein kinase Lck2.7.10.20.469
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.469
4jajXU1Aurora kinase A2.7.11.10.469
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.469
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.468
1uyrD1LAcetyl-CoA carboxylase/0.468
2izrBRKCasein kinase I isoform gamma-32.7.11.10.468
2yixYIXMitogen-activated protein kinase 14/0.468
3cwkREACellular retinoic acid-binding protein 2/0.468
4b99R4LMitogen-activated protein kinase 72.7.11.240.468
4btkDTQTau-tubulin kinase 12.7.11.10.468
4g2fC07Ephrin type-A receptor 32.7.10.10.468
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.468
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.468
4z34ON7Lysophosphatidic acid receptor 1/0.468
1cdeGARPhosphoribosylglycinamide formyltransferase/0.467
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.467
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.467
3t2kFADSulfide-quinone reductase/0.467
4kaoKAOFocal adhesion kinase 12.7.10.20.467
4l4aCAMCamphor 5-monooxygenase1.14.15.10.467
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.467
4oplFDAConserved Archaeal protein/0.467
4qnaX11Serine/threonine-protein kinase 242.7.11.10.467
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.466
1osvCHCBile acid receptor/0.466
2aibERGBeta-elicitin cinnamomin/0.466
2ghlLIBMitogen-activated protein kinase 14/0.466
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.466
2i0ePDSProtein kinase C beta type2.7.11.130.466
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.466
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.466
3nj0PYVAbscisic acid receptor PYL2/0.466
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.466
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.466
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.466
5k2bZMAAdenosine receptor A2a/0.466
1mduATPActin, alpha skeletal muscle/0.465
1pjkANPCasein kinase II subunit alpha2.7.11.10.465
1tcwIM1Gag-Pol polyprotein/0.465
2c475IDCasein kinase I isoform gamma-2/0.465
2izsBRQCasein kinase I isoform gamma-32.7.11.10.465
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.465
3cppCAMCamphor 5-monooxygenase1.14.15.10.465
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.465
4aqc88ATyrosine-protein kinase JAK2/0.465
4ic7ANPMitogen-activated protein kinase 72.7.11.240.465
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.465
5iu86DZAdenosine receptor A2a/0.465
1db1VDXVitamin D3 receptor/0.464
2btsU32Cyclin-dependent kinase 22.7.11.220.464
2itqITQEpidermal growth factor receptor2.7.10.10.464
2upjU02Gag-Pol polyprotein3.4.23.160.464
2vx17X8Ephrin type-B receptor 42.7.10.10.464
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.464
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.464
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.464
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.464
4c02TAKActivin receptor type-12.7.11.300.464
4c58824Cyclin-G-associated kinase2.7.11.10.464
4mxaBK7Calmodulin-like domain protein kinase isoenzyme gamma, related/0.464
1bl6SB6Mitogen-activated protein kinase 14/0.463
1bvgDMPGag-Pol polyprotein3.4.23.160.463
1phePIYCamphor 5-monooxygenase1.14.15.10.463
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
2py3ACPFibroblast growth factor receptor 2/0.463
2vynNADGlyceraldehyde-3-phosphate dehydrogenase A/0.463
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.463
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.463
3iaeD7KBenzaldehyde lyase/0.463
3w0qANPHygromycin-B 4-O-kinase2.7.1.1630.463
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.463
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.463
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.463
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.463
4oauADP2-5A-dependent ribonuclease3.1.260.463
5jtbZMAAdenosine receptor A2a/0.463
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.462
3fwfCAMCamphor 5-monooxygenase1.14.15.10.462
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.462
4e730NRMitogen-activated protein kinase 82.7.11.240.462
4ewqMWLMitogen-activated protein kinase 14/0.462
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.462
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.462
4pd6URINucleoside permease/0.462
5k2aZMAAdenosine receptor A2a/0.462
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1g4tFTPThiamine-phosphate synthase/0.461
1mesDMPGag-Pol polyprotein3.4.23.160.461
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.461
1yt9OISGag-Pol polyprotein/0.461
2eb3ANPEpidermal growth factor receptor2.7.10.10.461
2qo9ANPEphrin type-A receptor 32.7.10.10.461
2zawCAMCamphor 5-monooxygenase1.14.15.10.461
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.461
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.461
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.461
3wd7COAAcridone synthase/0.461
4cp4CAMCamphor 5-monooxygenase1.14.15.10.461
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.461
4g1wG1WMitogen-activated protein kinase 82.7.11.240.461
4gk3L87Ephrin type-A receptor 32.7.10.10.461
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.461
4l4dCAMCamphor 5-monooxygenase1.14.15.10.461
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.460
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.460
1ztfXYARIO-type serine/threonine-protein kinase Rio12.7.11.10.460
2feuCAMCamphor 5-monooxygenase1.14.15.10.460
2pvyACPFibroblast growth factor receptor 2/0.460
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.460
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3gi6D78Gag-Pol polyprotein/0.460
3q5dGDPAtlastin-13.6.50.460
4b1vATPActin, alpha skeletal muscle/0.460
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.460
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.460
4fv7E94Mitogen-activated protein kinase 12.7.11.240.460
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.460
1b15NAEAlcohol dehydrogenase1.1.1.10.459
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.459
3i0rRT3Gag-Pol polyprotein2.7.7.490.459
3pe2E1BCasein kinase II subunit alpha2.7.11.10.459
3r9nZ68Cyclin-dependent kinase 22.7.11.220.459
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.459
4fidGDPG protein alpha subunit, putative/0.459
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.459
4loqSB4Mitogen-activated protein kinase 14/0.459
5cp4CAMCamphor 5-monooxygenase1.14.15.10.459
5cvfATPCasein kinase II subunit alpha2.7.11.10.459
5uviZMAAdenosine receptor A2a/0.459
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
2cig1DGDihydrofolate reductase1.5.1.30.458
2cppCAMCamphor 5-monooxygenase1.14.15.10.458
2gtmLIDMitogen-activated protein kinase 14/0.458
2iw84SPCyclin-dependent kinase 22.7.11.220.458
2q3kMUWGag-Pol polyprotein/0.458
3vquO22Dual specificity protein kinase TTK2.7.12.10.458
4i22IREEpidermal growth factor receptor2.7.10.10.458
4nb6444Nuclear receptor ROR-gamma/0.458
4okx198Androgen receptor/0.458
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.458
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4zseANPEpidermal growth factor receptor2.7.10.10.458
1ke6LS2Cyclin-dependent kinase 22.7.11.220.457
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.457
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.457
2excJNKMitogen-activated protein kinase 102.7.11.240.457
2ituITQEpidermal growth factor receptor2.7.10.10.457
2j0m4STFocal adhesion kinase 12.7.10.20.457
2obyNAPQuinone oxidoreductase PIG310.457
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.457
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.457
2ydoADNAdenosine receptor A2a/0.457
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.457
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.457
3hng8STVascular endothelial growth factor receptor 12.7.10.10.457
3mgdACOPredicted acetyltransferase/0.457
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.457
3obgSB2Mitogen-activated protein kinase 14/0.457
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
3tqhNDPQuinone oxidoreductase/0.457
3ufnROCGag-Pol polyprotein/0.457
3upjU03Gag-Pol polyprotein/0.457
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.457
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.456
1tl1H18Gag-Pol polyprotein2.7.7.490.456
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.456
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
3lpbNVBTyrosine-protein kinase JAK2/0.456
3t2yFADSulfide-quinone reductase/0.456
3w2sW2REpidermal growth factor receptor2.7.10.10.456
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4f9wLM4Mitogen-activated protein kinase 14/0.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
4ienCOAPutative acyl-CoA hydrolase/0.456
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.456
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.456
1fk9EFZGag-Pol polyprotein2.7.7.490.455
1qbsDMPGag-Pol polyprotein3.4.23.160.455
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.455
2ewaSB2Mitogen-activated protein kinase 14/0.455
2jn3JN3Fatty acid-binding protein, liver/0.455
2rf2MRXGag-Pol polyprotein2.7.7.490.455
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2yaaATPDeath-associated protein kinase 2/0.455
2yn8STUEphrin type-B receptor 42.7.10.10.455
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.455
3uyt0CKCasein kinase I isoform delta2.7.11.10.455
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4c9pCAMCytochrome P450/0.455
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.455
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.455
4riyADPEpidermal growth factor receptor2.7.10.10.455
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.455
1eh4IC1Casein kinase I homolog 12.7.11.10.454
1k6cMK1Gag-Pol polyprotein3.4.23.160.454
1q3ePCGPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.454
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.454
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.454
3bhy7CPDeath-associated protein kinase 3/0.454
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.454
3gstGPRGlutathione S-transferase Mu 12.5.1.180.454
3hv3R49Mitogen-activated protein kinase 14/0.454
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
3zh8C58Protein kinase C iota type2.7.11.130.454
4b1uLABActin, alpha skeletal muscle/0.454
4dpwAGSMevalonate diphosphate decarboxylase/0.454
4gk4L90Ephrin type-A receptor 32.7.10.10.454
4jrvKJVEpidermal growth factor receptor2.7.10.10.454
5aut2ANDeath-associated protein kinase 12.7.11.10.454
1dz4CAMCamphor 5-monooxygenase1.14.15.10.453
1ie3NADMalate dehydrogenase/0.453
1pkdUCNCyclin-dependent kinase 22.7.11.220.453
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.453
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.453
1vjy460TGF-beta receptor type-12.7.11.300.453
2a1mCAMCamphor 5-monooxygenase1.14.15.10.453
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.453
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.453
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.453
2q631UNGag-Pol polyprotein3.4.23.160.453
2qd7065Gag-Pol polyprotein3.4.23.160.453
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.453
2w6nOA2Biotin carboxylase6.3.4.140.453
2wdzNADGalactitol dehydrogenase/0.453
2yfxVGHALK tyrosine kinase receptor2.7.10.10.453
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.453
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.453
3g0eB49Mast/stem cell growth factor receptor Kit2.7.10.10.453
3njoPYVAbscisic acid receptor PYR1/0.453
3oc1BMUMitogen-activated protein kinase 14/0.453
3oom507Activin receptor type-12.7.11.300.453
3opdHIEHeat shock protein 83/0.453
3oquA8SAbscisic acid receptor PYL9/0.453
3qlrNDPDihydrofolate reductase1.5.1.30.453
3uleC69Actin-related protein 3/0.453
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.453
4d4sBI9Focal adhesion kinase 12.7.10.20.453
4dce0JFALK tyrosine kinase receptor2.7.10.10.453
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4l9i8PRRhodopsin kinase/0.453
4twnB96Ephrin type-A receptor 32.7.10.10.453
5f2kSAHUncharacterized protein/0.453
5iu4ZMAAdenosine receptor A2a/0.453
5iua6DXAdenosine receptor A2a/0.453
1errRALEstrogen receptor/0.452
1hzzNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.452
1mg5NAIAlcohol dehydrogenase1.1.1.10.452
1n4hREANuclear receptor ROR-beta/0.452
1rt4UC1Gag-Pol polyprotein2.7.7.490.452
1w2xRCPAcetyl-CoA carboxylase/0.452
1z1rHBHGag-Pol polyprotein3.4.23.160.452
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.452
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2hog710Serine/threonine-protein kinase Chk12.7.11.10.452
2j7t274Serine/threonine-protein kinase 102.7.11.10.452
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.452
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.452
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.452
3gggNADPrephenate dehydrogenase/0.452
3hub469Mitogen-activated protein kinase 14/0.452
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.452
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.452
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3sa8K83Protease/0.452
4bb432WEphrin type-B receptor 42.7.10.10.452
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.452
4qmuSKESerine/threonine-protein kinase 242.7.11.10.452
1r9oFLPCytochrome P450 2C9/0.451
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.451
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
1w0xOLOCyclin-dependent kinase 22.7.11.220.451
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.451
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.451
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2ft9CHDFatty acid-binding protein 2, liver/0.451
2pwuGUNQueuine tRNA-ribosyltransferase2.4.2.290.451
2qhzMZ2Gag-Pol polyprotein/0.451
2rewREWPeroxisome proliferator-activated receptor alpha/0.451
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.451
3c4zADPRhodopsin kinase/0.451
3dagFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.451
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3lltANPProtein serine/threonine kinase-1/0.451
3w0iO11Vitamin D3 receptor/0.451
3zewSTUEphrin type-B receptor 42.7.10.10.451
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.451
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.451
4cd2FOLDihydrofolate reductase1.5.1.30.451
4l8u9AZSerum albumin/0.451
4nc3ERM5-hydroxytryptamine receptor 2B/0.451
4nmbFADBifunctional protein PutA/0.451
4tuvCPZCytochrome P450 1191.140.451
1b14NADAlcohol dehydrogenase1.1.1.10.450
1gii1PUCyclin-dependent kinase 22.7.11.220.450
1iwiCAMCamphor 5-monooxygenase1.14.15.10.450
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.450
1nzdUPGDNA beta-glucosyltransferase/0.450
2c27ACOMycothiol acetyltransferase2.3.1.1890.450
2cciATPCyclin-dependent kinase 22.7.11.220.450
2fxeDR7Gag-Pol polyprotein3.4.23.160.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2iidFADL-amino-acid oxidase1.4.3.20.450
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
2o0uC0MMitogen-activated protein kinase 102.7.11.240.450
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.450
2q55MU0Protease/0.450
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.450
3clyACPFibroblast growth factor receptor 2/0.450
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.450
3p7cP7CMitogen-activated protein kinase 14/0.450
3p7nFMNLight-activated DNA-binding protein EL222/0.450
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4a9e3PFBromodomain-containing protein 2/0.450
4kbc1QJCasein kinase I isoform delta2.7.11.10.450
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.450
4wkqIREEpidermal growth factor receptor2.7.10.10.450
4y8wSTRSteroid 21-hydroxylase/0.450
5dulNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.450
1bv7XV6Gag-Pol polyprotein3.4.23.160.449
1c0fATPMajor actin/0.449
1j39UPGDNA beta-glucosyltransferase/0.449
1ludTRRDihydrofolate reductase1.5.1.30.449
1mqbANPEphrin type-A receptor 22.7.10.10.449
1nvtNAPShikimate dehydrogenase (NADP(+))/0.449
1qbu846Gag-Pol polyprotein3.4.23.160.449
1tkzH16Gag-Pol polyprotein2.7.7.490.449
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.449
2a1oCAMCamphor 5-monooxygenase1.14.15.10.449
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
2p55MRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
2qbnCAMCamphor 5-monooxygenase1.14.15.10.449
3d84NDPDihydrofolate reductase1.5.1.30.449
3da1FADGlycerol-3-phosphate dehydrogenase/0.449
3ez2ADPPlasmid partition protein A/0.449
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.449
3m6gATPActin, alpha skeletal muscle/0.449
3poz03PEpidermal growth factor receptor2.7.10.10.449
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3s1cZIRCytokinin dehydrogenase 11.5.99.120.449
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.449
3uwqU5POrotidine 5'-phosphate decarboxylase/0.449
3w2rW2REpidermal growth factor receptor2.7.10.10.449
3w32W32Epidermal growth factor receptor2.7.10.10.449
4btmF8ETau-tubulin kinase 12.7.11.10.449
4ccuAWFALK tyrosine kinase receptor2.7.10.10.449
4ejmNAPPutative zinc-binding dehydrogenase/0.449
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.449
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.449
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.449
4l4bCAMCamphor 5-monooxygenase1.14.15.10.449
4mokFADPyranose 2-oxidase/0.449
1g69TZPThiamine-phosphate synthase/0.448
1m52P17Tyrosine-protein kinase ABL12.7.10.20.448
1ot7CHCBile acid receptor/0.448
1rbyGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.448
1t87CAMCamphor 5-monooxygenase1.14.15.10.448
1t88CAMCamphor 5-monooxygenase1.14.15.10.448
1tj1FADBifunctional protein PutA1.5.5.20.448
1zrzBI1Protein kinase C iota type2.7.11.130.448
2pyn1UNGag-Pol polyprotein3.4.23.160.448
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.448
2rh9IGPTryptophan synthase alpha chain/0.448
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.448
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.448
3ezvEZVCyclin-dependent kinase 22.7.11.220.448
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.448
3p84FMNPentaerythritol tetranitrate reductase/0.448
3ttjJBIMitogen-activated protein kinase 102.7.11.240.448
3v3vMYUMitogen-activated protein kinase 82.7.11.240.448
3vt45YIVitamin D3 receptor/0.448
3w9rA8SAbscisic acid receptor PYL9/0.448
3zsh469Mitogen-activated protein kinase 14/0.448
4alhA9PBromodomain-containing protein 2/0.448
4ek1CAMCamphor 5-monooxygenase1.14.15.10.448
4gb20LQGag-Pol polyprotein2.7.7.490.448
4gg70J8Hepatocyte growth factor receptor2.7.10.10.448
4gmy0X5Tyrosine-protein kinase JAK2/0.448
4i231C9Epidermal growth factor receptor2.7.10.10.448
4j54G52Gag-Pol polyprotein3.4.23.160.448
4kb81QOCasein kinase I isoform delta2.7.11.10.448
4l4xNDPAmphI/0.448
4lv7ADPInositol-pentakisphosphate 2-kinase2.7.1.1580.448
4uyf73BBromodomain-containing protein 2/0.448
5dr9SKEAurora kinase A2.7.11.10.448
1b16NAQAlcohol dehydrogenase1.1.1.10.447
1c2tGARPhosphoribosylglycinamide formyltransferase/0.447
1d7yFADFerredoxin reductase/0.447
1hpoUNIGag-Pol polyprotein3.4.23.160.447
1lriCLRBeta-elicitin cryptogein/0.447
1nhhANPDNA mismatch repair protein MutL/0.447
1nvfADPPentafunctional AROM polypeptide/0.447
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1tz8DESTransthyretin/0.447
1u54ACPActivated CDC42 kinase 1/0.447
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
1xqcAEJEstrogen receptor/0.447
1y4lSVRBasic phospholipase A2 homolog 2/0.447
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.447
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.447
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.447
2gr1FADFerredoxin reductase/0.447
2itvANPEpidermal growth factor receptor2.7.10.10.447
2o4rVD5Vitamin D3 receptor/0.447
2qblCAMCamphor 5-monooxygenase1.14.15.10.447
2qi7MZ9Gag-Pol polyprotein/0.447
2y05NAPProstaglandin reductase 1/0.447
3a783EVVitamin D3 receptor/0.447
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.447
3cktYDPGag-Pol polyprotein3.4.23.160.447
3em6017Gag-Pol polyprotein3.4.23.160.447
3gy0NAPNAD(P)-dependent oxidoreductase/0.447
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3t3c017Gag-Pol polyprotein3.4.23.160.447
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.447
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.447
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.447
4grb0XGCasein kinase II subunit alpha2.7.11.10.447
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.447
4q71FADBifunctional protein PutA/0.447
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.447
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1bygSTUTyrosine-protein kinase CSK/0.446
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.446
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1kvkATPMevalonate kinase2.7.1.360.446
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.446
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.446
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.446
1yinCM3Estrogen receptor/0.446
2ftoCB3Thymidylate synthase/0.446
2oz6CMPCyclic AMP receptor-like protein/0.446
2qhyMZ1Gag-Pol polyprotein/0.446
2vf0F89Thymidylate synthase/0.446
3at4CCKCasein kinase II subunit alpha2.7.11.10.446
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.446
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.446
3fmlFMLMitogen-activated protein kinase 14/0.446
3gbuATPUncharacterized sugar kinase PH14592.7.10.446
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.446
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.446
3nu5478Gag-Pol polyprotein3.4.23.160.446
3o9eA60Pol polyprotein/0.446
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.446
3q5iANPProtein kinase, putative/0.446
3r8uZ31Cyclin-dependent kinase 22.7.11.220.446
3sacAF8Protease/0.446
3vetADPnebramycin 5' synthase6.1.2.20.446
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.446
4eiyZMAAdenosine receptor A2a/0.446
4fhi0S4Vitamin D3 receptor A/0.446
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.446
4gt3ATPMitogen-activated protein kinase 12.7.11.240.446
4kbk1QGCasein kinase I isoform delta2.7.11.10.446
4lcf1WLUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.446
4lxhC1EAlpha/beta hydrolase fold/0.446
4z875GPInosine-5'-monophosphate dehydrogenase/0.446
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.446
5av2KMPDeath-associated protein kinase 12.7.11.10.446
4ea30NNNociceptin receptor/0.446
3qakUKAAdenosine receptor A2a/0.446
1chwHXCChalcone synthase 22.3.1.740.445
1dkfBMSRetinoic acid receptor alpha/0.445
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.445
1hetNADAlcohol dehydrogenase E chain1.1.1.10.445
1m2kAPRNAD-dependent protein deacylase 1/0.445
1ml3NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.445
1revTB9Gag-Pol polyprotein2.7.7.490.445
1sg6NADPentafunctional AROM polypeptide/0.445
2pmdGNPTranslation initiation factor 2 subunit gamma/0.445
2q0bACPFibroblast growth factor receptor 2/0.445
2q36ATPActin, alpha skeletal muscle/0.445
2vcmM11Isopenicillin N synthase1.21.3.10.445
2vg5NNCGag-Pol polyprotein2.7.7.490.445
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.445
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.445
2zb3NDPProstaglandin reductase 21.3.1.480.445
3aidARQGag-Pol polyprotein3.4.23.160.445
3axwTIDCasein kinase II subunit alpha2.7.11.10.445
3bgbLJGGag-Pol polyprotein3.4.23.160.445
3bheBZNGag-Pol polyprotein3.4.23.160.445
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.445
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.445
3hv6R39Mitogen-activated protein kinase 14/0.445
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qtsX46Cyclin-dependent kinase 22.7.11.220.445
3zuxTCHTransporter/0.445
4f081RSTyrosine-protein kinase JAK2/0.445
4fv9E71Mitogen-activated protein kinase 12.7.11.240.445
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.445
4njsG08Protease/0.445
4yagNAIC alpha-dehydrogenase/0.445
4yntFDAGlucose oxidase, putative/0.445
5av3KMPDeath-associated protein kinase 12.7.11.10.445
1g6cIFPThiamine-phosphate synthase/0.444
1h47C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.444
1ir3ANPInsulin receptor2.7.10.10.444
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.444
1t44ATPActin, alpha skeletal muscle/0.444
1wvxBD4Death-associated protein kinase 12.7.11.10.444
2f02ATPTagatose-6-phosphate kinase/0.444
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.444
2h96893Mitogen-activated protein kinase 82.7.11.240.444
2hb3GRLProtease/0.444
2hjrAPRMalate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase/0.444
2iw94SPCyclin-dependent kinase 22.7.11.220.444
2j5xGSPADP-ribosylation factor 6/0.444
2p5uNADUDP-glucose 4-epimerase/0.444
2vttLZDCyclin-dependent kinase 22.7.11.220.444
2w4iVGAGlutamate racemase/0.444
2wouZZFTGF-beta receptor type-12.7.11.300.444
3cz09ODPheromone-binding protein ASP1/0.444
3gxlQIGTGF-beta receptor type-12.7.11.300.444
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3m08RARDihydrofolate reductase1.5.1.30.444
3p7bP7BMitogen-activated protein kinase 14/0.444
3pg3DG7Mitogen-activated protein kinase 14/0.444
3qyw6PBMitogen-activated protein kinase 12.7.11.240.444
3s1dZIRCytokinin dehydrogenase 11.5.99.120.444
3so9017Pol protein/0.444
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.444
3vrwYS5Vitamin D3 receptor/0.444
3wmxNADNAD dependent epimerase/dehydratase/0.444
4aguD15Cyclin-dependent kinase-like 1/0.444
4bcmT7ZCyclin-dependent kinase 22.7.11.220.444
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.444
4hvh19RTyrosine-protein kinase JAK32.7.10.20.444
4hvi19STyrosine-protein kinase JAK32.7.10.20.444
4ia3BIVVitamin D3 receptor A/0.444
4icyFADPgaE/0.444
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.444
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
4xldBRLPeroxisome proliferator-activated receptor gamma/0.444
4z07PCGcGMP-dependent protein kinase 12.7.11.120.444
1c3eGARPhosphoribosylglycinamide formyltransferase/0.443
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.443
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.443
1g2kNM1Gag-Pol polyprotein3.4.23.160.443
1jkkANPDeath-associated protein kinase 12.7.11.10.443
1kzjCB3Thymidylate synthase/0.443
1ptjSNDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
1rkhVD2Vitamin D3 receptor/0.443
1sh9RITGag-Pol polyprotein3.4.23.160.443
1t85CAMCamphor 5-monooxygenase1.14.15.10.443
1u3cFADCryptochrome-1/0.443
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2b9wFADPutative aminooxidase/0.443
2d8aNADL-threonine 3-dehydrogenase/0.443
2etm7PYFocal adhesion kinase 12.7.10.20.443
2hyySTITyrosine-protein kinase ABL12.7.10.20.443
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.443
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.443
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
2w06FRVCyclin-dependent kinase 22.7.11.220.443
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.443
2x7hPFNProstaglandin reductase 310.443
2zgzGNPPlasmid segregation protein ParM/0.443
3a4pDFQHepatocyte growth factor receptor2.7.10.10.443
3eqlMXPDNA-directed RNA polymerase subunit beta/0.443
3eqlMXPDNA-directed RNA polymerase subunit beta'/0.443
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.443
3h0sB38Acetyl-CoA carboxylase/0.443
3lm9ADPPutative fructokinase2.7.1.40.443
3lsiFADPyranose 2-oxidase/0.443
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3mxeK54Gag-Pol polyprotein3.4.23.160.443
3orpAGSSerine/threonine protein kinase/0.443
3slkNDPPolyketide synthase extender module 2/0.443
3zep1NXTyrosine-protein kinase JAK32.7.10.20.443
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.443
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
4fhh0U3Vitamin D3 receptor A/0.443
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.443
4zolACPTubulin tyrosine ligase/0.443
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4z35ON9Lysophosphatidic acid receptor 1/0.443
1aq1STUCyclin-dependent kinase 22.7.11.220.442
1fwkADPHomoserine kinase2.7.1.390.442
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.442
1w84L12Mitogen-activated protein kinase 14/0.442
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.442
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.442
2gqfFADUncharacterized protein HI_0933/0.442
2ittAEEEpidermal growth factor receptor2.7.10.10.442
2izuP01Casein kinase I isoform gamma-32.7.11.10.442
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.442
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.442
2pwcG3GGag-Pol polyprotein3.4.23.160.442
2q61SF1Peroxisome proliferator-activated receptor gamma/0.442
2qnpQN2Gag-Pol polyprotein3.4.23.160.442
2vww7X2Ephrin type-B receptor 42.7.10.10.442
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.442
2yyyNAPGlyceraldehyde-3-phosphate dehydrogenase1.2.1.590.442
3a62STURibosomal protein S6 kinase beta-12.7.11.10.442
3aoxEMHALK tyrosine kinase receptor2.7.10.10.442
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.442
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
3kddJZQGag-Pol polyprotein3.4.23.160.442
3o9gF53Gag-Pol polyprotein/0.442
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.442
3saa77FProtease/0.442
3sheI85MAP kinase-activated protein kinase 32.7.11.10.442
3t113T1Gag-Pol polyprotein3.4.23.160.442
4fkv61KCyclin-dependent kinase 22.7.11.220.442
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fuxE75Mitogen-activated protein kinase 12.7.11.240.442
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.442
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4hgs15GCasein kinase I isoform gamma-32.7.11.10.442
4ib4ERM5-hydroxytryptamine receptor 2B/0.442
4j55031Gag-Pol polyprotein3.4.23.160.442
4plpNADHomospermidine synthase2.5.1.440.442
4s34ANPMitogen-activated protein kinase 12.7.11.240.442
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
4uhrNGIAdenosine receptor A2a/0.442
4ug2NGIAdenosine receptor A2a/0.442
1bdlIM1Gag-Pol polyprotein3.4.23.160.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1fvt106Cyclin-dependent kinase 22.7.11.220.441
1h1vATPActin, alpha skeletal muscle/0.441
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1h50FMNPentaerythritol tetranitrate reductase/0.441
1hvyD16Thymidylate synthase2.1.1.450.441
1iy8NADLevodione reductase/0.441
1pmn984Mitogen-activated protein kinase 102.7.11.240.441
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.441
1pp9SMACytochrome b/0.441
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1sduMK1Gag-Pol polyprotein3.4.23.160.441
1u28NADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.441
1u30GOXPancreatic alpha-amylase/0.441
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.441
1w5xBE5Gag-Pol polyprotein3.4.23.160.441
1wvySTUDeath-associated protein kinase 12.7.11.10.441
2ban357Gag-Pol polyprotein2.7.7.490.441
2cvvANPRibonucleoside-diphosphate reductase large chain 11.17.4.10.441
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2hasC3OVitamin D3 receptor/0.441
2pc4ASP_TRP_ASNFructose-bisphosphate aldolase4.1.2.130.441
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.441
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.441
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.441
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.441
2ydwWSHBromodomain-containing protein 2/0.441
2zgyGDPPlasmid segregation protein ParM/0.441
3a4vNADNDP-sugar epimerase/0.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3c4wATPRhodopsin kinase/0.441
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3evaSAHGenome polyprotein2.1.1.560.441
3h9f92MDual specificity protein kinase TTK2.7.12.10.441
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3o9fK2DGag-Pol polyprotein/0.441
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.441
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.441
3sabF78Protease/0.441
3ukrCKHActin-related protein 3/0.441
3ukrCKHActin-related protein 2/0.441
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.441
3wv9FEGHmd co-occurring protein HcgE/0.441
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.441
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.441
4iebANPCalmodulin-domain protein kinase 1/0.441
4iteTEYVitamin D3 receptor/0.441
4kb81QNCasein kinase I isoform delta2.7.11.10.441
4mleVO1Glucokinase2.7.1.20.441
4o2bLOCTubulin beta-2B chain/0.441
4pkiATPActin, alpha skeletal muscle/0.441
4q73FADBifunctional protein PutA/0.441
4zhxC1V5'-AMP-activated protein kinase catalytic subunit alpha-2/0.441
4zhxC1V5'-AMP-activated protein kinase subunit beta-1/0.441
1kgjFL8Transthyretin/0.440
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1z95198Androgen receptor/0.440
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.440
2c3qGTXGlutathione S-transferase theta-12.5.1.180.440
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.440
2pmnK51Protein kinase 7/0.440
2pzrACPFibroblast growth factor receptor 2/0.440
2vrx447Aurora kinase B-A2.7.11.10.440
2xa4AZ5Tyrosine-protein kinase JAK2/0.440
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.440
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.440
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.440
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3mec65BGag-Pol polyprotein2.7.7.490.440
3p5kP5KMitogen-activated protein kinase 14/0.440
3p82FMNPentaerythritol tetranitrate reductase/0.440
3q9yTXQCasein kinase II subunit alpha2.7.11.10.440
3r28XA0Cyclin-dependent kinase 22.7.11.220.440
3r8zZ63Cyclin-dependent kinase 22.7.11.220.440
3ttiKBIMitogen-activated protein kinase 102.7.11.240.440
3vruYS3Vitamin D3 receptor/0.440
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.440
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.440
3zptM8YGag-Pol polyprotein3.4.23.160.440
4aotGW8Serine/threonine-protein kinase 102.7.11.10.440
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4b1fKRHGlutamate racemase/0.440
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.440
4dc0NDPPutative ketoacyl reductase1.3.10.440
4dqb017Gag-Pol polyprotein/0.440
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.440
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.440
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.440
4gevCB3Thymidylate synthase/0.440
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.440
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.440
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.440
4qms1N1Serine/threonine-protein kinase 242.7.11.10.440
4wlvNADMalate dehydrogenase, mitochondrial1.1.1.370.440
5aacVGHALK tyrosine kinase receptor2.7.10.10.440
5ap57RODual specificity protein kinase TTK2.7.12.10.440