sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kz1 | GSP | Transforming protein RhoA |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3kz1 | GSP | Transforming protein RhoA | / | 1.000 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.563 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.562 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.540 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.534 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.521 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.519 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.519 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.511 | |
| 4mit | GTP | Rho-related protein racC | / | 0.511 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.503 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.495 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.493 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.488 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.488 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.483 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.478 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.474 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.473 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.472 | |
| 3i3s | GNP | GTPase HRas | / | 0.471 | |
| 3lbn | GNP | GTPase HRas | / | 0.470 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.464 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.464 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.462 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.461 | |
| 3oiv | GNP | GTPase HRas | / | 0.461 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.460 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.456 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.455 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.453 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.452 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.450 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.449 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.448 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.443 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.443 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.441 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.440 |