Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3kucGDPRas-related protein Rap-1A

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3kucGDPRas-related protein Rap-1A/1.000
3oivGNPGTPase HRas/0.579
3oiuGNPGTPase HRas/0.551
1m7bGTPRho-related GTP-binding protein RhoE/0.537
5b2zGNPGTPase HRas/0.537
3lbnGNPGTPase HRas/0.536
1zc3GNPRas-related protein Ral-A/0.523
1zc4GNPRas-related protein Ral-A/0.514
3i3sGNPGTPase HRas/0.511
3rs5GNPGTPase HRas/0.511
1oixGDPRas-related protein Rab-11A/0.504
1kmqGNPTransforming protein RhoA/0.499
3v4fGNPGTPase HRas/0.496
4dltGNPGTPase HRas/0.494
1xtsGTPGTP-binding protein Rheb/0.492
4nyjGNPGTPase HRas/0.490
4nyiGNPGTPase HRas/0.489
4dlwGNPGTPase HRas/0.483
1xtrGNPGTP-binding protein Rheb/0.478
4mitGTPRho-related protein racC/0.476
3ddcGNPGTPase HRas/0.475
4dxaGSPRas-related protein Rap-1b/0.473
3kz1GSPTransforming protein RhoA/0.472
1uadGNPRas-related protein Ral-A/0.471
3rs7GNPGTPase HRas/0.469
2rgeGNPGTPase HRas/0.465
2clsGTPRho-related GTP-binding protein Rho6/0.462
3oesGNPGTPase RhebL1/0.461
5dhaGNPGTP-binding nuclear protein Ran/0.459
4cymGCPRas-related protein Rab-32/0.458
4xoiGTPTransforming protein RhoA/0.457
1cxzGSPTransforming protein RhoA/0.456
4kvgGTPRas-related protein Rap-1A/0.456
1g17GNPRas-related protein SEC4/0.451
3e5hGNPRas-related protein Rab-28/0.446
3w3zGTPGTP-binding nuclear protein Ran/0.446
2fe4GDPRas-related protein Rab-6B/0.445
3a58GNPGTP-binding protein RHO1/0.443
3rabGNPRas-related protein Rab-3A/0.442
2gcpGSPRho-related GTP-binding protein RhoC/0.441
4dsnGCPGTPase KRas/0.441
4qxaGTPRas-related protein Rab-9A/0.441
1s1cGNPTransforming protein RhoA/0.440