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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.581.000
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.779
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.674
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.652
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.645
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.635
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.635
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.631
1s63778Protein farnesyltransferase subunit beta2.5.1.580.629
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.625
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.624
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.621
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.619
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.610
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.602
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.593
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.587
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.578
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.554
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.533
3q7fED2Uncharacterized protein/0.511
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.505
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.497
3sfy3FYUncharacterized protein/0.490
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.487
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.484
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.481
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.472
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.469
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.457
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.457
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.454
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.452
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.445
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.445
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.443
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441