sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3k3j | F4C | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3k3j | F4C | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3p79 | P79 | Mitogen-activated protein kinase 14 | / | 0.675 | |
| 3p5k | P5K | Mitogen-activated protein kinase 14 | / | 0.656 | |
| 3hv7 | 1AU | Mitogen-activated protein kinase 14 | / | 0.643 | |
| 2puu | G2G | Mitogen-activated protein kinase 14 | / | 0.637 | |
| 3p7b | P7B | Mitogen-activated protein kinase 14 | / | 0.630 | |
| 3nnx | EDD | Mitogen-activated protein kinase 14 | / | 0.625 | |
| 3o8u | BMU | Mitogen-activated protein kinase 14 | / | 0.621 | |
| 3gi3 | B10 | Mitogen-activated protein kinase 14 | / | 0.619 | |
| 1kv1 | BMU | Mitogen-activated protein kinase 14 | / | 0.608 | |
| 3uvr | 06F | Mitogen-activated protein kinase 14 | / | 0.605 | |
| 3e93 | 19B | Mitogen-activated protein kinase 14 | / | 0.601 | |
| 3nnu | EDB | Mitogen-activated protein kinase 14 | / | 0.591 | |
| 4l8m | F46 | Mitogen-activated protein kinase 14 | / | 0.554 | |
| 4aa0 | AA0 | Mitogen-activated protein kinase 14 | / | 0.551 | |
| 3hv4 | L51 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 1wbv | LI3 | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 3gcu | R48 | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 3wze | BAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.527 | |
| 3npc | B96 | Mitogen-activated protein kinase 9 | 2.7.11.24 | 0.517 | |
| 1wbn | L09 | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 3p78 | P78 | Mitogen-activated protein kinase 14 | / | 0.508 | |
| 3ugc | 046 | Tyrosine-protein kinase JAK2 | / | 0.502 | |
| 4u0i | 0LI | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.497 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.490 | |
| 3d83 | GK6 | Mitogen-activated protein kinase 14 | / | 0.490 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.485 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.483 | |
| 1c70 | L75 | Protease | / | 0.482 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.482 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.482 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.482 | |
| 3nnw | EDD | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.479 | |
| 5hi2 | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.479 | |
| 2hs2 | 017 | Protease | / | 0.478 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.476 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 3nu9 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 1w82 | L10 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 1c6x | 3IN | Protease | / | 0.473 | |
| 2bpx | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 1mer | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 3sa9 | A68 | Protease | / | 0.471 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 3eky | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 3v01 | 3V0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.469 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.466 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.466 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2qnn | QN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 3d1x | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.466 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.465 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.465 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 1bai | 0Q4 | Gag-Pro polyprotein | / | 0.464 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.464 | |
| 1z1h | HBB | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 2aid | THK | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.464 | |
| 3o9a | K14 | Pol polyprotein | / | 0.464 | |
| 3s54 | 017 | Protease | / | 0.464 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.464 | |
| 1dmp | DMQ | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 1mrx | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2bpz | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 3liv | E16 | Protease | / | 0.463 | |
| 1hxw | RIT | Gag-Pol polyprotein | / | 0.462 | |
| 2avs | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 2qnp | QN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 1b6k | PI5 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2uy0 | HV1 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 3djk | G55 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 4njt | 017 | Protease | / | 0.461 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.461 | |
| 1ebw | BEI | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.460 | |
| 1hwr | 216 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1jst | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1sdu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.459 | |
| 2q55 | MU0 | Protease | / | 0.459 | |
| 2r38 | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 2i4x | KGQ | Protease | / | 0.458 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.458 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1w5x | BE5 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2f3k | RO1 | Protease | / | 0.457 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.457 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4an3 | 5Y0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.457 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.457 | |
| 4k4p | 3TL | Gag-Pol polyprotein | / | 0.457 | |
| 1ebz | BEC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2hz0 | GIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.456 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3o8p | BMU | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1mes | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2b7z | MK1 | Gag-Pol polyprotein | / | 0.455 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.455 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.455 | |
| 3nu6 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3nxe | 2NC | Protease | / | 0.455 | |
| 3o9d | K19 | Pol polyprotein | / | 0.455 | |
| 1d4y | TPV | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.454 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.454 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2hiw | 7MP | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.454 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.454 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3jvw | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1b6p | PI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1hvk | A79 | Gag-Pol polyprotein | / | 0.453 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.453 | |
| 2f80 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2q5k | AB1 | Protease | / | 0.453 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.453 | |
| 3qbf | JHG | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.453 | |
| 4s34 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1tcx | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1wbk | 568 | Pol protein | / | 0.452 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.452 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2ieo | 017 | Protease | / | 0.452 | |
| 2qhz | MZ2 | Gag-Pol polyprotein | / | 0.452 | |
| 2uxz | HI1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2yiw | YIW | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.452 | |
| 4dqb | 017 | Gag-Pol polyprotein | / | 0.452 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.451 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.451 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2fdd | 385 | Pol protein | / | 0.451 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.451 | |
| 2qhc | AB1 | Protease | / | 0.451 | |
| 3ndu | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.451 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.450 | |
| 1ivp | 1ZK | Gag-Pol polyprotein | / | 0.450 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.450 | |
| 3d20 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3epo | MP5 | Phosphomethylpyrimidine synthase | / | 0.450 | |
| 3mws | 017 | Pol protein | / | 0.450 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3qih | FG7 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 1c6y | MK1 | Protease | / | 0.449 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.449 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.449 | |
| 1qbs | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2acw | UPG | Glycosyltransferase | / | 0.449 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2fxd | DR7 | Pol polyprotein | / | 0.449 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.449 | |
| 3o9g | F53 | Gag-Pol polyprotein | / | 0.449 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 9hvp | 0E9 | Gag-Pol polyprotein | / | 0.449 | |
| 1ida | 0PO | Gag-Pol polyprotein | 3.4.23.47 | 0.448 | |
| 1met | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1w5v | BE3 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2nnp | ROC | Protease | / | 0.448 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.448 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.448 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1bdq | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1izi | Q50 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2hc0 | AB2 | Protease | / | 0.447 | |
| 2i4v | DJR | V-1 protease | / | 0.447 | |
| 2pwr | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3lit | E15 | Protease | / | 0.447 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.447 | |
| 1ajx | AH1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1dw6 | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1hpv | 478 | Gag-Pol polyprotein | / | 0.446 | |
| 1hvj | A78 | Gag-Pol polyprotein | / | 0.446 | |
| 1jf7 | TBH | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.446 | |
| 1k2c | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1qbt | 146 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1t3r | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1wbm | BLL | Pol protein | / | 0.446 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 2pyn | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2qi1 | MZ4 | Gag-Pol polyprotein | / | 0.446 | |
| 2qi6 | MZ8 | Gag-Pol polyprotein | / | 0.446 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.446 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3lzv | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3oxw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3tl9 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 4q1y | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 1daz | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1hvi | A77 | Protease | / | 0.445 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.445 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2xyf | G40 | Gag-Pol polyprotein | / | 0.445 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 3lq5 | SLQ | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.445 | |
| 3o99 | K13 | Pol polyprotein | / | 0.445 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4jrn | ANP | Rhoptry kinase family protein | / | 0.445 | |
| 4l7s | G7K | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 1d4j | MSC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.444 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.444 | |
| 1wvy | STU | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.444 | |
| 3ndx | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3vf5 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.444 | |
| 4dqe | 017 | Gag-Pol polyprotein | / | 0.444 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.444 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1dif | A85 | Gag-Pol polyprotein | / | 0.443 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.443 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.443 | |
| 1qbr | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.443 | |
| 2psv | MUV | Protease | / | 0.443 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.443 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.443 | |
| 3ekv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.443 | |
| 3oxc | ROC | Protease | / | 0.443 | |
| 3oxx | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3qih | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.443 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4ei7 | GDP | Plasmid replication protein RepX | / | 0.443 | |
| 4s32 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 1hvr | XK2 | Gag-Pol polyprotein | / | 0.442 | |
| 1k2b | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2a4f | AAU | V-1 protease | / | 0.442 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.442 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.442 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 3d1z | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3gi4 | K60 | Gag-Pol polyprotein | / | 0.442 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3ucb | 017 | Gag-Pol polyprotein | / | 0.442 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.442 | |
| 1bwa | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1d4k | PI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.441 | |
| 2idw | 017 | Protease | / | 0.441 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.441 | |
| 2r5p | MK1 | Gag-Pol polyprotein | / | 0.441 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3bxs | DRS | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3kf0 | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.441 | |
| 3o9c | K20 | Pol polyprotein | / | 0.441 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.441 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.441 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4djq | M86 | Pol polyprotein | / | 0.441 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.440 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.440 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.440 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.440 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.440 | |
| 2nmy | ROC | Protease | / | 0.440 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.440 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 3em4 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3kfn | 3TL | Gag-Pol polyprotein | / | 0.440 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3r71 | X86 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 |