sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.826 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.772 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.745 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.585 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.580 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.574 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.572 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.572 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.566 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.566 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.557 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.546 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.539 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.531 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.525 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.522 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.521 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.515 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.512 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.507 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.505 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.500 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.499 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.494 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.493 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.475 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.474 | |
| 4iae | 1DX | Alr2278 protein | / | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.473 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.473 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.472 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.471 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.471 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.466 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.466 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.465 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.465 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.465 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 4iah | 1DX | Alr2278 protein | / | 0.464 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.461 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.459 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.457 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.457 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.456 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.454 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.452 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.452 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.452 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.452 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.452 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.451 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.449 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.449 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.448 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.448 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.448 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.448 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.448 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.447 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.447 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.446 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.445 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.445 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.444 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.444 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.443 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.443 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.442 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.442 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 4boe | CLR | Japanin | / | 0.442 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.442 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.441 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.440 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.440 |