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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3jt7H4BNitric oxide synthase, brain1.14.13.39

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3jwuH4BNitric oxide synthase, brain1.14.13.390.589
3pnf8BXNitric oxide synthase, brain1.14.13.390.549
4jsiQ05Nitric oxide synthase, brain1.14.13.390.518
3n5xXFKNitric oxide synthase, brain1.14.13.390.504
3b3oJI3Nitric oxide synthase, brain1.14.13.390.476