Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3jrxS1AAcetyl-CoA carboxylase 2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3jrxS1AAcetyl-CoA carboxylase 2/1.000
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4j6cSTRCytochrome P450 monooxygenase/0.453
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3hk1B64Fatty acid-binding protein, adipocyte/0.445
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441