sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 1.000 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.641 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.568 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.516 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.487 | |
| 4aw3 | MYV | Mycinamicin IV hydroxylase/epoxidase | / | 0.456 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.445 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.444 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.443 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 |