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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3iczPB6Farnesyl pyrophosphate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3iczPB6Farnesyl pyrophosphate synthase/1.000
4h5dYS4Farnesyl pyrophosphate synthase2.5.1.100.556
4h5eYS4Farnesyl pyrophosphate synthase2.5.1.100.555
4demYS4Farnesyl pyrophosphate synthase2.5.1.100.537
4ga34GAFarnesyl pyrophosphate synthase2.5.1.100.525
3egt722Farnesyl pyrophosphate synthase/0.524
4h5cYS4Farnesyl pyrophosphate synthase2.5.1.100.518
4l2xYL2Farnesyl pyrophosphate synthase2.5.1.100.509
4lfvYS4Farnesyl pyrophosphate synthase2.5.1.100.506
4jvj1MVFarnesyl pyrophosphate synthase2.5.1.100.489
3dyh721Farnesyl pyrophosphate synthase/0.486
1zw5ZOLFarnesyl pyrophosphate synthase2.5.1.100.480
3rywK9HFarnesyl pyrophosphate synthase, putative/0.479
2opmNI9Farnesyl pyrophosphate synthase2.5.1.100.477
3oabDSTGeranyl diphosphate synthase large subunit/0.474
2opnSUFFarnesyl pyrophosphate synthase2.5.1.100.455
3ez3ZOLFarnesyl pyrophosphate synthase, putative/0.451
5ej4TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
1qf5RPLAdenylosuccinate synthetase/0.444
1mjbACOHistone acetyltransferase ESA1/0.440