sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3i28	34N	Bifunctional epoxide hydrolase 2	3.3.2.10

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3i28	34N	Bifunctional epoxide hydrolase 2	3.3.2.10	1.000
3i1y	33N	Bifunctional epoxide hydrolase 2	3.3.2.10	0.551
4l4f	CAM	Camphor 5-monooxygenase	1.14.15.1	0.461
1dz6	CAM	Camphor 5-monooxygenase	1.14.15.1	0.456
4cax	MYA	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.453
3ozd	4CT	S-methyl-5'-thioadenosine phosphorylase	/	0.446
5jy1	NAD	Putative short-chain dehydrogenase/reductase	/	0.444
1kqn	NAD	Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1	2.7.7.1	0.442
3mdv	CL6	Cholesterol 24-hydroxylase	/	0.441
3uzw	NAP	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.441