sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3hna	SAH	Histone-lysine N-methyltransferase EHMT1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3hna	SAH	Histone-lysine N-methyltransferase EHMT1	/	1.000
5jin	SAM	Histone-lysine N-methyltransferase EHMT2	/	0.599
5jhn	SAM	Histone-lysine N-methyltransferase EHMT2	/	0.590
5jj0	SAM	Histone-lysine N-methyltransferase EHMT2	/	0.587
3mo0	SAH	Histone-lysine N-methyltransferase EHMT1	/	0.565
3fpd	SAH	Histone-lysine N-methyltransferase EHMT1	/	0.564
2o8j	SAH	Histone-lysine N-methyltransferase EHMT2	/	0.545
3mo5	E72	Histone-lysine N-methyltransferase EHMT1	/	0.529
2igq	SAH	Histone-lysine N-methyltransferase EHMT1	/	0.479
3kmt	SAH	Histone H3K27 methylase	/	0.477