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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.53

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.531.000
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.532
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.521
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.501
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.494
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.493
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.491
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.485
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.481
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
3v94WYQPhosphodiesterase/0.463
4phlPILPhosphodiesterase/0.460
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.441
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440