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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3hlwCE3Beta-lactamase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3hlwCE3Beta-lactamase/1.000
4de00JBBeta-lactamase/0.648
4ddyDN6Beta-lactamase/0.638
4de10J6Beta-lactamase/0.631
4de2DN3Beta-lactamase/0.626
4de3DN8Beta-lactamase/0.609
3q1fYPPBeta-lactamase/0.565
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.520
3t4eNADQuinate/shikimate dehydrogenase/0.511
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.510
4f9gC2EStimulator of interferon genes protein/0.509
4d89BXDBeta-secretase 13.4.23.460.508
1umaIN2Prothrombin3.4.21.50.506
4w5kPLPAspartate aminotransferase, mitochondrial/0.506
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.504
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.502
4lxa1YSBeta-secretase 13.4.23.460.499
3cic316Beta-secretase 13.4.23.460.497
4i1iNADMalate dehydrogenase/0.497
3gqvNAPEnoyl reductase LovC10.496
2hfuMEVMevalonate kinase/0.495
3vg10GTBeta-secretase 13.4.23.460.495
4dbzNDPPutative ketoacyl reductase1.3.10.495
2fj1CTCTetracycline repressor protein class D/0.494
2o12FMNChorismate synthase/0.494
2ylrNAPPhenylacetone monooxygenase1.14.13.920.494
3f3sNADLambda-crystallin homolog/0.494
3k5c0BIBeta-secretase 13.4.23.460.494
4lcjNADC-terminal-binding protein 2/0.494
1ra8FOLDihydrofolate reductase1.5.1.30.493
1vhzAPRADP compounds hydrolase NudE3.6.10.493
3d3xARG_ILE_MET_GLU_NH2Type E botulinum toxin/0.493
4x5iFOLDihydrofolate reductase1.5.1.30.493
2c20NADUDP-glucose 4-epimerase/0.492
2iyfERYOleandomycin glycosyltransferase2.4.10.492
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.492
1xe65FPPlasmepsin-23.4.23.390.491
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.491
3atzFMNProstaglandin F2a synthase/0.491
3gkaFMNN-ethylmaleimide reductase/0.491
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.491
1t2cNAIL-lactate dehydrogenase1.1.1.270.490
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.490
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.490
3uyk0CXProbable NDP-rhamnosyltransferase/0.490
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.489
1icsFMN12-oxophytodienoate reductase 11.3.1.420.489
2gywOBIAcetylcholinesterase3.1.1.70.489
2qbuSAHPrecorrin-2 methyltransferase/0.489
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.488
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.487
2a92NAIL-lactate dehydrogenase/0.487
2wf1ZY1Beta-secretase 13.4.23.460.487
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.487
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.487
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.487
3h06VBPGlutamate receptor 2/0.487
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.487
3ziuLSSLeucyl-tRNA synthetase/0.487
4bfxZVXPantothenate kinase2.7.1.330.487
4df2FMNNADPH dehydrogenase/0.487
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.486
4gid0GHBeta-secretase 13.4.23.460.486
1j49NADD-lactate dehydrogenase1.1.1.280.485
1odcA8BAcetylcholinesterase3.1.1.70.485
2abbFMNPentaerythritol tetranitrate reductase/0.485
2wezZYEBeta-secretase 13.4.23.460.485
3b70NAPEnoyl reductase LovC10.485
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.485
4du82P0Mevalonate diphosphate decarboxylase/0.485
4k8s1QTBeta-secretase 13.4.23.460.485
4k9h1QUBeta-secretase 13.4.23.460.485
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.484
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.484
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.483
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.483
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.483
1ddrMTXDihydrofolate reductase1.5.1.30.482
1h50FMNPentaerythritol tetranitrate reductase/0.482
1xelUPGUDP-glucose 4-epimerase5.1.3.20.482
2a9y26AAdenosine kinase2.7.1.200.482
2f3rG5PGuanylate kinase2.7.4.80.482
3fr5I4AFatty acid-binding protein, adipocyte/0.482
3pi53P5Beta-secretase 13.4.23.460.482
4oztP1AEcdysone receptor, putative/0.482
4q0kGA3Phytohormone-binding protein/0.482
1o9bNAIQuinate/shikimate dehydrogenase/0.481
2c12FADNitroalkane oxidase1.7.3.10.481
2ylzFADPhenylacetone monooxygenase1.14.13.920.481
3rsv3RSBeta-secretase 13.4.23.460.481
2vkeTACTetracycline repressor protein class D/0.480
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.480
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.480
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.480
2ohvNHLGlutamate racemase/0.479
3rpeFADPutative modulator of drug activity/0.479
4ewo996Beta-secretase 13.4.23.460.479
4hyvPEPPyruvate kinase 12.7.1.400.479
4opgFDAConserved Archaeal protein/0.479
1psa0ZLPepsin A3.4.23.10.478
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.478
2gv8NDPThiol-specific monooxygenase1.14.130.478
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.478
3b6zCO7Enoyl reductase LovC10.478
3c1y2BADNA integrity scanning protein DisA/0.478
3c27DKKProthrombin3.4.21.50.478
3eksCY9Actin-5C/0.478
3hyoADPPyridoxal kinase/0.478
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.478
3lqfNADGalactitol dehydrogenase/0.478
1w34FADFerredoxin--NADP reductase1.18.1.20.477
1xe55FEPlasmepsin-23.4.23.390.477
3gfbNADL-threonine 3-dehydrogenase/0.477
3p62FMNPentaerythritol tetranitrate reductase/0.477
4b63NAPL-ornithine N(5)-monooxygenase/0.477
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.477
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.476
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.476
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.476
2dftADPShikimate kinase2.7.1.710.476
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.476
3atyFMNProstaglandin F2a synthase/0.476
3cid318Beta-secretase 13.4.23.460.476
3kkjFADRenalase/0.476
3lpkZ76Beta-secretase 13.4.23.460.476
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.476
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.476
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.476
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.476
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.476
4jicFMNGTN Reductase/0.476
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.476
4xbjIN5Alanine racemase, biosynthetic/0.476
5dhgDGVNociceptin receptor/0.476
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.475
1udaUFGUDP-glucose 4-epimerase5.1.3.20.475
2a94AP0L-lactate dehydrogenase1.1.1.270.475
2futH1SHeparin and heparin-sulfate lyase/0.475
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.475
2zvcSAHPrecorrin-3 C17-methyltransferase/0.475
3a0tADPSensor histidine kinase/0.475
3a3gDLZLumazine protein/0.475
4dptAGSMevalonate diphosphate decarboxylase/0.475
1rneC60Renin3.4.23.150.474
1szgFNSCytochrome b2, mitochondrial1.1.2.30.474
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.474
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.474
2gjlFMNNitronate monooxygenase1.13.12.160.474
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.474
2rlcCHDCholoylglycine hydrolase3.5.1.240.474
4e2dFMNDehydrogenase/0.474
4eb5PLPCysteine desulfurase IscS 2/0.474
4f5yC2EStimulator of interferon genes protein/0.474
4m4922YL-lactate dehydrogenase A chain1.1.1.270.474
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.474
1eveE20Acetylcholinesterase3.1.1.70.473
1g1aNADdTDP-glucose 4,6-dehydratase/0.473
1kszPGSAdenylosuccinate synthetase/0.473
1w6rGNTAcetylcholinesterase3.1.1.70.473
1x1bSAHC-20 methyltransferase/0.473
2a7r5GPGMP reductase 2/0.473
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.473
2v7qATPATP synthase subunit alpha, mitochondrial/0.473
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.473
3clsFADElectron transfer flavoprotein subunit alpha/0.473
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.473
3phiNDPShikimate dehydrogenase (NADP(+))/0.473
3q43D66M1 family aminopeptidase3.4.110.473
3w6hAZMCarbonic anhydrase 14.2.1.10.473
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.473
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.473
1a59COA2-methylcitrate synthase/0.472
1culFOKAdenylate cyclase type 2/0.472
1culFOKAdenylate cyclase type 5/0.472
1d2hSAHGlycine N-methyltransferase2.1.1.200.472
1mjaCOAHistone acetyltransferase ESA1/0.472
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.472
1rfuADPPyridoxal kinase2.7.1.350.472
1zgbA1EAcetylcholinesterase3.1.1.70.472
2xukTZ5Acetylcholinesterase3.1.1.70.472
3i0pNADMalate dehydrogenase, putative/0.472
3k5fAYHBeta-secretase 13.4.23.460.472
3veu0GOBeta-secretase 13.4.23.460.472
3wqmB29Diterpene synthase3.1.7.80.472
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.472
4m5pFMNNADPH dehydrogenase/0.472
4m83ERYOleandomycin glycosyltransferase2.4.10.472
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.472
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.472
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.472
5ah5LSSLeucine--tRNA ligase/0.472
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.471
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
2vijC44Beta-secretase 13.4.23.460.471
3d91REMRenin3.4.23.150.471
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.471
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.471
3uayADNPurine nucleoside phosphorylase DeoD-type/0.471
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.471
4h1e10JBeta-secretase 13.4.23.460.471
4lxk1YTBeta-secretase 13.4.23.460.471
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.471
1bim0QBRenin3.4.23.150.470
1h74ADPHomoserine kinase2.7.1.390.470
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.470
1pq944BOxysterols receptor LXR-beta/0.470
1ra3MTXDihydrofolate reductase1.5.1.30.470
1w6hTITPlasmepsin-23.4.23.390.470
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2cndFADNitrate reductase [NADH]1.7.1.10.470
2xuoTZ4Acetylcholinesterase3.1.1.70.470
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.470
3p67FMNPentaerythritol tetranitrate reductase/0.470
3r9uFADThioredoxin reductase/0.470
3skgPB8Beta-secretase 13.4.23.460.470
3to6LYS_CMCHistone acetyltransferase ESA1/0.470
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.470
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.470
4ef4C2EStimulator of interferon genes protein/0.470
4l4xNDPAmphI/0.470
5itzLOCTubulin beta-2B chain/0.470
1cscCMCCitrate synthase, mitochondrial2.3.3.10.469
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.469
1vf3GDNGlutathione S-transferase 32.5.1.180.469
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.469
2g1n1IGRenin3.4.23.150.469
2g1s4IGRenin3.4.23.150.469
2omeNADC-terminal-binding protein 2/0.469
2rcyNAPPyrroline-5-carboxylate reductase/0.469
2viyVG3Beta-secretase 13.4.23.460.469
3ai3NDPNADPH-sorbose reductase/0.469
3bk2U5PRibonuclease J/0.469
3f1kNAPUncharacterized oxidoreductase YciK10.469
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.469
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.469
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.469
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.468
1i5cADPChemotaxis protein CheA2.7.13.30.468
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.468
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2b58COADiamine acetyltransferase 1/0.468
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.468
3lpiZ74Beta-secretase 13.4.23.460.468
3p8jFMNPentaerythritol tetranitrate reductase/0.468
3r2fPB0Beta-secretase 13.4.23.460.468
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.468
5itzGTPTubulin alpha-1B chain/0.468
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.467
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.467
2g8yNADHydroxycarboxylate dehydrogenase B/0.467
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.467
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.467
4djy0KRBeta-secretase 13.4.23.460.467
4exg916Beta-secretase 13.4.23.460.467
4u3jGTPTubulin beta chain/0.467
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.467
4yj2GTPTubulin alpha-1B chain/0.467
1bwlFMNNADPH dehydrogenase 11.6.99.10.466
1dyjDDFDihydrofolate reductase1.5.1.30.466
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.466
1mueCDDProthrombin3.4.21.50.466
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.466
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.466
1vjtNADAlpha-glucosidase, putative/0.466
2anb5GPGuanylate kinase2.7.4.80.466
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.466
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.466
2j3qTFLAcetylcholinesterase3.1.1.70.466
2p4j23IBeta-secretase 13.4.23.460.466
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3mauEXTPutative sphingosine-1-phosphate lyase/0.466
3tjzGNPADP-ribosylation factor 1/0.466
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.466
1h73ANPHomoserine kinase2.7.1.390.465
1j9zFADNADPH--cytochrome P450 reductase/0.465
1tqf32PBeta-secretase 13.4.23.460.465
1x1aSAMC-20 methyltransferase/0.465
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.465
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.465
2gjnFMNNitronate monooxygenase1.13.12.160.465
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.465
2vyqFADFerredoxin--NADP reductase1.18.1.20.465
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.465
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.465
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.465
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.465
3fpjSAMUncharacterized protein/0.465
3in6FMNUncharacterized protein/0.465
3nmpPYVAbscisic acid receptor PYL2/0.465
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.465
4acxS8ZBeta-secretase 13.4.23.460.465
4e2bFMNDehydrogenase/0.465
4ey7E20Acetylcholinesterase3.1.1.70.465
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.465
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.465
1h63FMNPentaerythritol tetranitrate reductase/0.464
1xs7MMIBeta-secretase 13.4.23.460.464
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.464
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.464
2cftPLPPyridoxal phosphate phosphatase/0.464
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.464
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.464
2oahQINBeta-secretase 13.4.23.460.464
2v16C47Renin3.4.23.150.464
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.464
3hf3FMNChromate reductase/0.464
3k5dXLIBeta-secretase 13.4.23.460.464
3vf30GSBeta-secretase 13.4.23.460.464
4b1rITCTetracycline repressor protein class D/0.464
4blrUTPNTPase P4/0.464
4j0v1H7Beta-secretase 13.4.23.460.464
4m9aFDAAcyl-CoA dehydrogenase/0.464
4wriOKAOkadaic acid binding protein 2-alpha/0.464
1dyiFOLDihydrofolate reductase1.5.1.30.463
2bsxNOSPurine nucleoside phosphorylase/0.463
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.463
2cv2GSUGlutamate--tRNA ligase6.1.1.170.463
2dxiATPGlutamate--tRNA ligase6.1.1.170.463
2eklNADD-3-phosphoglycerate dehydrogenase/0.463
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.463
2pciSAHDiphthine synthase/0.463
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.463
2wf4ZY4Beta-secretase 13.4.23.460.463
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.463
3nl6TPSUncharacterized protein/0.463
3q9bB3NAcetylpolyamine amidohydrolase/0.463
4bftZVTPantothenate kinase2.7.1.330.463
4d03FADPhenylacetone monooxygenase1.14.13.920.463
4dieC5PCytidylate kinase/0.463
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.463
4loi1YCStimulator of interferon genes protein/0.463
4opiFDAConserved Archaeal protein/0.463
4xguADPPutative pachytene checkpoint protein 2/0.463
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.462
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.462
1v0jFADUDP-galactopyranose mutase5.4.99.90.462
1xvaSAMGlycine N-methyltransferase2.1.1.200.462
1ygkRRCPyridoxal kinase2.7.1.350.462
2ejvNADL-threonine 3-dehydrogenase/0.462
2hk9NAPShikimate dehydrogenase (NADP(+))/0.462
2ou2ACOHistone acetyltransferase KAT5/0.462
2y0mACOHistone acetyltransferase KAT8/0.462
3h3qH13Collagen type IV alpha-3-binding protein/0.462
3ixk929Beta-secretase 13.4.23.460.462
4friDWABeta-secretase 13.4.23.460.462
4j7hTRHPCZA361.3/0.462
4jc51K5Stimulator of interferon genes protein/0.462
4ke11R6Beta-secretase 13.4.23.460.462
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.462
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.462
4qxp1YEStimulator of interferon genes protein/0.462
4v2gITCTetracycline repressor protein class D/0.462
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.462
5d3qGDPDynamin-13.6.5.50.462
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.461
1ex75GPGuanylate kinase2.7.4.80.461
1me6IVSPlasmepsin-23.4.23.390.461
1vi2NADQuinate/shikimate dehydrogenase/0.461
1w4xFADPhenylacetone monooxygenase1.14.13.920.461
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.461
2bjfDXCCholoylglycine hydrolase3.5.1.240.461
2briANPUridylate kinase2.7.4.220.461
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.461
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.461
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.461
2g247IGRenin3.4.23.150.461
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.461
2zsaADPPantothenate kinase2.7.1.330.461
3ohh3HHBeta-secretase 13.4.23.460.461
3oibFDAPutative acyl-CoA dehydrogenase/0.461
3oixFMNDihydroorotate dehydrogenase/0.461
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.461
4b7754MBeta-secretase 13.4.23.460.461
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.461
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.461
4k6fNAPPutative Acetoacetyl-CoA reductase/0.461
4lol1YEStimulator of interferon genes protein/0.461
4lutDCSAlanine racemase/0.461
4yvz3ATDNA integrity scanning protein DisA/0.461
5kwvANPPantothenate synthetase/0.461
1icpFMN12-oxophytodienoate reductase 11.3.1.420.460
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.460
1xddAAYIntegrin alpha-L/0.460
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.460
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.460
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.460
2ffqGSPRas-related protein Rab-6B/0.460
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.460
2r8oT5XTransketolase 1/0.460
2tctCTCTetracycline repressor protein class D/0.460
3duyAFJBeta-secretase 13.4.23.460.460
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3fql79ZGenome polyprotein2.7.7.480.460
3r96ACOMccE protein/0.460
3udn09BBeta-secretase 13.4.23.460.460
4araC56Acetylcholinesterase3.1.1.70.460
4e5yNDPGDP-L-fucose synthase1.1.1.2710.460
4nauAGSPhosphopantetheine adenylyltransferase/0.460
1jwtBLIProthrombin3.4.21.50.459
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.459
1o6zNADMalate dehydrogenase/0.459
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.459
1szfFMNCytochrome b2, mitochondrial1.1.2.30.459
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.459
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.459
2f3fAXFBeta-secretase 13.4.23.460.459
2g1o2IGRenin3.4.23.150.459
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.459
2qimZEAClass 10 plant pathogenesis-related protein/0.459
3ixj586Beta-secretase 13.4.23.460.459
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.459
3k5gBJCBeta-secretase 13.4.23.460.459
3nutSAHPrecorrin-3 methylase/0.459
4h4wFADBiphenyl dioxygenase ferredoxin reductase subunit/0.459
4kgkGTPUncharacterized protein/0.459
4lh71X8DNA ligase/0.459
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.459
4qaiFMNNADPH dehydrogenase/0.459
4u0mATPCyclic GMP-AMP synthase/0.459
6tmn0PIThermolysin3.4.24.270.459
1bwsNDPGDP-L-fucose synthase/0.458
1k02FMNNADPH dehydrogenase 11.6.99.10.458
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.458
1r5gAO1Methionine aminopeptidase 2/0.458
1s4pGDPGlycolipid 2-alpha-mannosyltransferase/0.458
2freFMNNAD(P)H-flavin oxidoreductase/0.458
2g1y5IGRenin3.4.23.150.458
2givACOHistone acetyltransferase KAT8/0.458
2gyuHI6Acetylcholinesterase3.1.1.70.458
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.458
3djjFADGlutathione reductase, mitochondrial1.8.1.70.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3h86AP5Adenylate kinase/0.458
3intGDUUDP-galactopyranose mutase5.4.99.90.458
3p82FMNPentaerythritol tetranitrate reductase/0.458
3rn8RN8Glutamate receptor 2/0.458
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.458
4cf7ADPAdenylate kinase/0.458
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.458
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.458
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.458
4j4nD44Peptidylprolyl isomerase/0.458
4j75TYMTryptophan--tRNA ligase/0.458
1e66HUXAcetylcholinesterase3.1.1.70.457
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1npdNADQuinate/shikimate dehydrogenase/0.457
1ut6A8NAcetylcholinesterase3.1.1.70.457
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2bbwGP5Adenylate kinase 4, mitochondrial/0.457
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2hm1LIQBeta-secretase 13.4.23.460.457
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.457
3au2DGTDNA polymerase beta family (X family)/0.457
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.457
3cib314Beta-secretase 13.4.23.460.457
3kpbSAMUncharacterized protein MJ0100/0.457
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.457
3ov7ATPCCA-adding enzyme2.7.7.720.457
3qt62P0Mevalonate diphosphate decarboxylase/0.457
3toxNAPPutative oxidoreductase/0.457
3wquATPCell division protein FtsA/0.457
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.457
1drhNAPDihydrofolate reductase1.5.1.30.456
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.456
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.456
1udbUFGUDP-glucose 4-epimerase5.1.3.20.456
1uvsI11Prothrombin3.4.21.50.456
1yqsBSAD-alanyl-D-alanine carboxypeptidase3.4.16.40.456
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.456
2cbrA80Cellular retinoic acid-binding protein 1/0.456
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.456
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.456
2zfp19UProthrombin3.4.21.50.456
3aezGDPPantothenate kinase2.7.1.330.456
3cwqADPParA family chromosome partitioning protein/0.456
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.456
3vyfVYFRenin3.4.23.150.456
4acuQN7Beta-secretase 13.4.23.460.456
4arbC57Acetylcholinesterase3.1.1.70.456
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.456
4dpi0N1Beta-secretase 13.4.23.460.456
4e2wJHZMethyltransferase/0.456
4f6rGDPTubulin beta chain/0.456
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.456
4qxq1YEStimulator of interferon genes protein/0.456
4x5jFOLDihydrofolate reductase1.5.1.30.456
5jscFADPutative acyl-CoA dehydrogenase/0.456
1i6kTYMTryptophan--tRNA ligase6.1.1.20.455
1mjbACOHistone acetyltransferase ESA1/0.455
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.455
1nb6UTPGenome polyprotein2.7.7.480.455
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.455
2cy0NAPShikimate dehydrogenase (NADP(+))/0.455
2gz7D3FOrf1a polyprotein/0.455
2ikuLIYRenin3.4.23.150.455
2il2LIXRenin3.4.23.150.455
2iqgF2IBeta-secretase 13.4.23.460.455
2j2pSC2Ficolin-2/0.455
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.455
3opxU5PSuppressor of disruption of TFIIS/0.455
3qlsNDPDihydrofolate reductase1.5.1.30.455
3vydVYDRenin3.4.23.150.455
3zidGDPTubulin-like protein CetZ/0.455
4dfg0JVGag-Pol polyprotein3.4.23.160.455
4qxaGTPRas-related protein Rab-9A/0.455
4r1lADPPhenylacetate-coenzyme A ligase/0.455
4rnuFMNNADPH dehydrogenase 11.6.99.10.455
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.455
4x28FDAAcyl-CoA dehydrogenase FadE26/0.455
4x28FDAAcyl-CoA dehydrogenase FadE27/0.455
4yqfGDPSeptin-9/0.455
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.455
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.455
1a8rGTPGTP cyclohydrolase 13.5.4.160.454
1gotGDPGuanine nucleotide-binding protein G(t) subunit alpha-1/0.454
1h51FMNPentaerythritol tetranitrate reductase/0.454
1jd0AZMCarbonic anhydrase 124.2.1.10.454
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.454
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.454
1ra3NAPDihydrofolate reductase1.5.1.30.454
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.454
2ehlSAHDiphthine synthase/0.454
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.454
2iko7IGRenin3.4.23.150.454
2jahNDPClavaldehyde dehydrogenase/0.454
2ldbNADL-lactate dehydrogenase1.1.1.270.454
2oapANPType II secretion system protein (GspE-2)/0.454
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
2vj6VG5Beta-secretase 13.4.23.460.454
2wf2ZY2Beta-secretase 13.4.23.460.454
2zgb21UProthrombin3.4.21.50.454
2zvbSAHPrecorrin-3 C17-methyltransferase/0.454
2zz0FADThioredoxin reductase 1, cytoplasmic1.8.1.90.454
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.454
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.454
3hl0NADMaleylacetate reductase/0.454
3iaaTYDCalG2/0.454
3oqfS51Renin3.4.23.150.454
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.454
3tozNADShikimate dehydrogenase (NADP(+))/0.454
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.454
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.454
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.454
5ftfADPTPR domain protein/0.454
1ddsMTXDihydrofolate reductase1.5.1.30.453
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.453
1icqFMN12-oxophytodienoate reductase 11.3.1.420.453
1t4u81AProthrombin3.4.21.50.453
1zgi382Prothrombin3.4.21.50.453
2drcMTXDihydrofolate reductase1.5.1.30.453
2en5SAHDiphthine synthase/0.453
2g21L1BRenin3.4.23.150.453
2pb4SAHDiphthine synthase/0.453
2vojNADAlanine dehydrogenase1.4.1.10.453
3f03FMNPentaerythritol tetranitrate reductase/0.453
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.453
3r95ACOMccE protein/0.453
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.453
4ambDUDPutative glycosyl transferase/0.453
4awsFMNNADH:flavin oxidoreductase Sye1/0.453
4d03NAPPhenylacetone monooxygenase1.14.13.920.453
4dc0NDPPutative ketoacyl reductase1.3.10.453
4egbNADdTDP-glucose 4,6-dehydratase/0.453
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.453
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.453
4y9qC2EUncharacterized protein/0.453
4yxm2BADNA integrity scanning protein DisA/0.453
1daaPLPD-alanine aminotransferase2.6.1.210.452
1g6kNADGlucose 1-dehydrogenase1.1.1.470.452
1ipeNDPTropinone reductase 21.1.1.2360.452
1kh3ANPArgininosuccinate synthase/0.452
1rb3MTXDihydrofolate reductase1.5.1.30.452
1re7FOLDihydrofolate reductase1.5.1.30.452
1u2yGOXPancreatic alpha-amylase/0.452
1wziNDPMalate dehydrogenase/0.452
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.452
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.452
2dvlFADAcyl-CoA dehydrogenase/0.452
2e8qSAHDiphthine synthase/0.452
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.452
2gesCOKPantothenate kinase2.7.1.330.452
2whqHI6Acetylcholinesterase3.1.1.70.452
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.452
2zcvNDPQuinone oxidoreductase 21.6.5.20.452
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3ekuCY9Actin-5C/0.452
3f63GTXGlutathione transferase GST1-4/0.452
3gwdNAPCyclohexanone monooxygenase/0.452
3v0o4GWHisto-blood group ABO system transferase/0.452
4a862ANMajor pollen allergen Bet v 1-A/0.452
4bfvZVVPantothenate kinase2.7.1.330.452
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.452
4h1vGNPDynamin-1-like protein3.6.5.50.452
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.452
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.452
4k28NADShikimate dehydrogenase family protein/0.452
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.452
1a8pFADFerredoxin--NADP reductase/0.451
1bil0IURenin3.4.23.150.451
1h60STRPentaerythritol tetranitrate reductase/0.451
1mj9COAHistone acetyltransferase ESA1/0.451
1nlyAGSCag alpha/0.451
1qy5NECEndoplasmin/0.451
1rfvADPPyridoxal kinase2.7.1.350.451
1typFADTrypanothione reductase1.8.1.120.451
2b7aIZATyrosine-protein kinase JAK2/0.451
2dsgSAHDiphthine synthase/0.451
2el3SAHDiphthine synthase/0.451
2g1r3IGRenin3.4.23.150.451
2ha6SCKAcetylcholinesterase3.1.1.70.451
2he5NDPAldo-keto reductase family 1 member C211.1.10.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.451
2rgoFADAlpha-Glycerophosphate Oxidase/0.451
2vkvTDCTetracycline repressor protein class D/0.451
2zff53UProthrombin3.4.21.50.451
3a1nNADNDP-sugar epimerase/0.451
3enkUPGUDP-glucose 4-epimerase/0.451
3kkzSAMUncharacterized protein/0.451
3mvzBHNNickel-binding periplasmic protein/0.451
3nd6ATPPhosphopantetheine adenylyltransferase/0.451
3och2MXDihydrofolate reductase1.5.1.30.451
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.451
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.451
4avlTMPPolymerase acidic protein/0.451
4b79NADProbable short-chain dehydrogenase/0.451
4dfrMTXDihydrofolate reductase1.5.1.30.451
4i0h1BLBeta-secretase 13.4.23.460.451
5fl3ADPPili retraction protein PilT/0.451
1cnfFADNitrate reductase [NADH]1.7.1.10.450
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.450
1h22E10Acetylcholinesterase3.1.1.70.450
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.450
1lbcCYZGlutamate receptor 2/0.450
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.450
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.450
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.450
1owe675Urokinase-type plasminogen activator3.4.21.730.450
1yhjR6CPyridoxal kinase2.7.1.350.450
1z48FMNNADPH dehydrogenase/0.450
2b3dFADModulator of drug activity B/0.450
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.450
2dfvNADL-threonine 3-dehydrogenase/0.450
2ea2F77Methionine aminopeptidase 2/0.450
2ejzSAHDiphthine synthase/0.450
2f3eAXQBeta-secretase 13.4.23.460.450
2fdpFRPBeta-secretase 13.4.23.460.450
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.450
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.450
2vuuNAPNitrogen metabolite repression protein nmrA/0.450
2xuhTZ4Acetylcholinesterase3.1.1.70.450
2znq401Peroxisome proliferator-activated receptor delta/0.450
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.450
3b1dPLSBetaC-S lyase/0.450
3eq02TSProthrombin3.4.21.50.450
3h2sNDPPutative NADH-flavin reductase/0.450
3h7rNAPAldo-keto reductase family 4 member C8/0.450
3i25MV7Beta-secretase 13.4.23.460.450
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.450
3lpjZ75Beta-secretase 13.4.23.460.450
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.450
3qvpFADGlucose oxidase1.1.3.40.450
3tneRITCandidapepsin-13.4.23.240.450
3tr05GPGuanylate kinase/0.450
4b7zQ4QAcetylcholinesterase3.1.1.70.450
4eb7PLPCysteine desulfurase IscS 2/0.450
4ey6GNTAcetylcholinesterase3.1.1.70.450
4h3i10VBeta-secretase 13.4.23.460.450
4uocNCNCinA-like protein/0.450
1a9cGTPGTP cyclohydrolase 13.5.4.160.449
1cg3IMOAdenylosuccinate synthetase/0.449
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.449
1hbvGANGag-Pol polyprotein/0.449
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.449
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.449
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.449
1rd7FOLDihydrofolate reductase1.5.1.30.449
1u65CP0Acetylcholinesterase3.1.1.70.449
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.449
2ab8MTPAdenosine kinase2.7.1.200.449
2ahrNAPPyrroline-5-carboxylate reductase/0.449
2hu2NADC-terminal binding protein 1/0.449
2qc8ADPGlutamine synthetase6.3.1.20.449
2qtcTDKPyruvate dehydrogenase E1 component1.2.4.10.449
2udpUPPUDP-glucose 4-epimerase5.1.3.20.449
2wf3ZY3Beta-secretase 13.4.23.460.449
2x8gFADThioredoxin glutathione reductase/0.449
2xpvMIYTetracycline repressor protein class D/0.449
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.449
3lqsPSZD-alanine aminotransferase2.6.1.210.449
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.449
4b1e6T6Beta-secretase 13.4.23.460.449
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.449
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.449
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.449
4tmcFMNOld yellow enzyme/0.449
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.449
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.448
1g9dBABBotulinum neurotoxin type B3.4.24.690.448
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.448
1ky2GNPGTP-binding protein YPT7/0.448
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.448
1q84TZ4Acetylcholinesterase3.1.1.70.448
1qf4RPDAdenylosuccinate synthetase/0.448
1rx8NAPDihydrofolate reductase1.5.1.30.448
1t91GTPRas-related protein Rab-7a/0.448
1wzeNADMalate dehydrogenase/0.448
2b53D23Cyclin-dependent kinase 22.7.11.220.448
2ed3SAHDiphthine synthase/0.448
2g226IGRenin3.4.23.150.448
2hizLIJBeta-secretase 13.4.23.460.448
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.448
2p6iSAHDiphthine synthase/0.448
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.448
2rc4ACOHistone acetyltransferase KAT6A/0.448
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.448
3fvlBHKCarboxypeptidase A13.4.17.10.448
3ihzFK5Peptidylprolyl isomerase/0.448
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.448
3toh079Gag-Pol polyprotein2.7.7.490.448
3u9eCOALmo1369 protein/0.448
3v2uATPProtein GAL3/0.448
4e32DWNMethyltransferase/0.448
4gh5NADShort-chain dehydrogenase/reductase SDR/0.448
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.448
4mkhAP5Adenylate kinase/0.448
4qnwFMNChanoclavine-I aldehyde reductase easA/0.448
4qxr1YEStimulator of interferon genes protein/0.448
4udrFAD5-(hydroxymethyl)furfural oxidase/0.448
4uugPXGBranched-chain amino acid aminotransferase, putative/0.448
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.448
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.448
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.448
5a3bAPRSIR2 family protein/0.448
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.448
5cfpC2EStimulator of interferon genes protein/0.448
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.448
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.447
1f8fNADBenzyl alcohol dehydrogenase/0.447
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
1kvrNADUDP-glucose 4-epimerase5.1.3.20.447
1rf7DHFDihydrofolate reductase1.5.1.30.447
1u3dFADCryptochrome-1/0.447
2c27ACOMycothiol acetyltransferase2.3.1.1890.447
2cekN8TAcetylcholinesterase3.1.1.70.447
2dc1NADProbable L-aspartate dehydrogenase/0.447
2geuCOKPantothenate kinase2.7.1.330.447
2owkSAHDiphthine synthase/0.447
2pswCOAN-alpha-acetyltransferase 50/0.447
2r2mI50Prothrombin3.4.21.50.447
2wjoQUDBeta-secretase 13.4.23.460.447
2xupTZ5Acetylcholinesterase3.1.1.70.447
2xuqTZ4Acetylcholinesterase3.1.1.70.447
3f7uAG4Carbonic anhydrase 44.2.1.10.447
3melTPPThiamin pyrophosphokinase family protein/0.447
3oadLPORenin3.4.23.150.447
3sxjSAMPutative methyltransferase/0.447
3ufl508Beta-secretase 13.4.23.460.447
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.447
4emtC2EStimulator of interferon genes protein/0.447
4fncHMUG/T mismatch-specific thymine DNA glycosylase3.2.2.290.447
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.447
5c41ACPRibokinase/0.447
1d4pBPPProthrombin3.4.21.50.446
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.446
1gtrATPGlutamine--tRNA ligase6.1.1.180.446
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.446
1qiqACCIsopenicillin N synthase1.21.3.10.446
1wuaAP8Actin, alpha skeletal muscle/0.446
1xvtCOAL-carnitine CoA-transferase/0.446
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.446
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2gilGTPRas-related protein Rab-6A/0.446
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2trtTACTetracycline repressor protein class D/0.446
2vprTDCTetracycline repressor protein class H/0.446
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.446
2xlrFADPutative flavin-containing monooxygenase/0.446
2ym2FADPhenylacetone monooxygenase1.14.13.920.446
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3ivgFG5Pantothenate synthetase6.3.2.10.446
3lzxFADFerredoxin--NADP reductase 21.18.1.20.446
3n19FNRXenobiotic reductase/0.446
3p19NDPPutative blue fluorescent protein/0.446
3slkNDPPolyketide synthase extender module 2/0.446
3t70DU4Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.446
3zv7NHGAcetylcholinesterase3.1.1.70.446
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.446
4fxy0W2Neurolysin, mitochondrial3.4.24.160.446
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.446
4ikeADPAdenylate kinase/0.446
4m6jNDPDihydrofolate reductase1.5.1.30.446
4mihFADPyranose 2-oxidase1.1.3.100.446
4wpuGDPPhosphoenolpyruvate carboxykinase [GTP]/0.446
4x5hFOLDihydrofolate reductase1.5.1.30.446
7kmeACE_0BN_CHG_PRRProthrombin3.4.21.50.446
1bk0ACVIsopenicillin N synthase1.21.3.10.445
1fy7COAHistone acetyltransferase ESA1/0.445
1hb1OCVIsopenicillin N synthase1.21.3.10.445
1hkuNADC-terminal-binding protein 11.1.10.445
1i5eU5PUracil phosphoribosyltransferase/0.445
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.445
1omoNADAlanine dehydrogenase/0.445
1qtiGNTAcetylcholinesterase3.1.1.70.445
1rjdSAMLeucine carboxyl methyltransferase 12.1.1.2330.445
1rx4DDFDihydrofolate reductase1.5.1.30.445
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.445
1u1iNADMyo-inositol-1-phosphate synthase (Ino1)/0.445
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.445
1z2iNADPutative malate dehydrogenase/0.445
1z7yAA5Cysteine synthase 12.5.1.470.445
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.445
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.445
2b8v3BNBeta-secretase 13.4.23.460.445
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.445
2ctsCOACitrate synthase, mitochondrial2.3.3.10.445
2e17SAHDiphthine synthase/0.445
2emrSAHDiphthine synthase/0.445
2fxuBIDActin, alpha skeletal muscle/0.445
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.445
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.445
2p6dSAHDiphthine synthase/0.445
2pncCLUPrimary amine oxidase, liver isozyme/0.445
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.445
2xufTZ4Acetylcholinesterase3.1.1.70.445
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.445
2z54AB1Gag-Pol polyprotein3.4.23.160.445
3akn11DFatty acid-binding protein, intestinal/0.445
3akzGSUGlutamate--tRNA ligase 2/0.445
3bg7FADPyranose 2-oxidase/0.445
3ibqATPPyridoxal kinase/0.445
3imgBZ3Pantothenate synthetase6.3.2.10.445
3l3mA92Poly [ADP-ribose] polymerase 12.4.2.300.445
3m4p4ADAsparaginyl-tRNA synthetase, putative/0.445
3mauPLRPutative sphingosine-1-phosphate lyase/0.445
3mz9BHNNickel-binding periplasmic protein/0.445
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.445
3q5lKX2Heat shock protein 83-1/0.445
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.445
3tog079Gag-Pol polyprotein2.7.7.490.445
3w8fNAD3-hydroxybutyrate dehydrogenase/0.445
4a802ANMajor pollen allergen Bet v 1-A/0.445
4fizCUE17beta-hydroxysteroid dehydrogenase/0.445
4frkDWDBeta-secretase 13.4.23.460.445
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.445
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.445
4tmbFMNOld yellow enzyme/0.445
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.445
1ay0TPPTransketolase 12.2.1.10.444
1dgmADNAdenosine kinase2.7.1.200.444
1qcwFNSCytochrome b2, mitochondrial1.1.2.30.444
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
1qyvNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.444
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.444
1u71MXADihydrofolate reductase1.5.1.30.444
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
2dhfDZFDihydrofolate reductase1.5.1.30.444
2dv4SAHDiphthine synthase/0.444
2ek7SAHDiphthine synthase/0.444
2hpvFMNFMN-dependent NADH-azoreductase1.70.444
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.444
2pb2PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.444
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.444
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.444
3bgxMEFThymidylate synthase/0.444
3e6eDCSAlanine racemase/0.444
3fktSIIBeta-secretase 13.4.23.460.444
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.444
3lzs017Gag-Pol polyprotein3.4.23.160.444
3muoZPRProlyl endopeptidase/0.444
3o26NDPSalutaridine reductase/0.444
3q2kNAIProbable oxidoreductase/0.444
4a8v2ANMajor pollen allergen Bet v 1-J/0.444
4a99FADTetX family tetracycline inactivation enzyme/0.444
4an4DUDPutative glycosyl transferase/0.444
4auxXTCTetracycline repressor protein class D/0.444
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.444
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.444
4frs0V6Beta-secretase 13.4.23.460.444
4kbyC2EStimulator of interferon genes protein/0.444
4l1xNAPAldo-keto reductase family 1 member C2/0.444
4rvdSAMD-mycarose 3-C-methyltransferase/0.444
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.444
1a5bIGPTryptophan synthase alpha chain/0.443
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1rj6AZMCarbonic anhydrase 144.2.1.10.443
1rp0AHZThiamine thiazole synthase, chloroplastic/0.443
1yqzCOACoenzyme A disulfide reductase/0.443
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.443
2abaSTRPentaerythritol tetranitrate reductase/0.443
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2dv3SAHDiphthine synthase/0.443
2ewvADPTwitching motility protein PilT/0.443
2p83MR0Beta-secretase 13.4.23.460.443
2qirCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.443
2vizVG4Beta-secretase 13.4.23.460.443
2w3bNDPDihydrofolate reductase1.5.1.30.443
2xfiXFIBeta-secretase 13.4.23.460.443
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.443
2xpwOTCTetracycline repressor protein class D/0.443
2z1mNDPGDP-mannose 4,6-dehydratase/0.443
2zr9DTPProtein RecA/0.443
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.443
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.443
3dmeFADPutative conserved exported protein/0.443
3fp0FP015-O-acetyltransferase/0.443
3g0bT22Dipeptidyl peptidase 4/0.443
3h3r14HCollagen type IV alpha-3-binding protein/0.443
3klbFMNUncharacterized protein/0.443
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.443
3nsh957Beta-secretase 13.4.23.460.443
3oetNADErythronate-4-phosphate dehydrogenase/0.443
3vdqNAD3-hydroxybutyrate dehydrogenase/0.443
3vhxGTPADP-ribosylation factor 6/0.443
3vyeVYERenin3.4.23.150.443
4do30LAFatty-acid amide hydrolase 13.5.1.990.443
4dx7DM2Multidrug efflux pump subunit AcrB/0.443
4i0i957Beta-secretase 13.4.23.460.443
4jq3NAPAldo-keto reductase family 1 member C2/0.443
4jtqNAPAldo-keto reductase family 1 member C2/0.443
4p9dTMPDeoxycytidylate deaminase/0.443
5a9sNAPPutative dehydrogenase/0.443
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.443
5esoISC2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
5fklTDCTetracycline repressor protein class D/0.443
5ilwURIRibosome inactivating protein/0.443
8dfrNDPDihydrofolate reductase1.5.1.30.443
1c6yMK1Protease/0.442
1e79ATPATP synthase subunit alpha, mitochondrial/0.442
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.442
1lkeDOGBilin-binding protein/0.442
1nfyRTRCoagulation factor X3.4.21.60.442
1ngsTPPTransketolase 12.2.1.10.442
1nvtNAPShikimate dehydrogenase (NADP(+))/0.442
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1xgiNSTBeta-lactamase3.5.2.60.442
2e77FMNLactate oxidase/0.442
2emuSAHDiphthine synthase/0.442
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.442
2ien017Gag-Pol polyprotein3.4.23.160.442
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.442
2xnvVU3Soluble acetylcholine receptor/0.442
3go4SAHUncharacterized protein/0.442
3ivmZPRProlyl endopeptidase/0.442
3k4nFADPyranose 2-oxidase/0.442
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
4djx0KQBeta-secretase 13.4.23.460.442
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.442
4f97VDOPutative glycosyltransferase/0.442
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.442
4ohwATPProtein clpf-1/0.442
4pghSAMCaffeic acid O-methyltransferase/0.442
4rvnCOAPhenylacetate-coenzyme A ligase/0.442
4wrkDUPDUTPase/0.442
5fwnNAPPutative dehydrogenase/0.442
6req3CPMethylmalonyl-CoA mutase large subunit5.4.99.20.442
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.441
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.441
1ghv120Prothrombin3.4.21.50.441
1h8hATPATP synthase subunit alpha, mitochondrial/0.441
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.441
1k7l544Peroxisome proliferator-activated receptor alpha/0.441
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.441
1l2sSTCBeta-lactamase3.5.2.60.441
1m4iCOAAminoglycoside 2'-N-acetyltransferase2.3.10.441
1p0hACOMycothiol acetyltransferase2.3.1.1890.441
1qf5RPLAdenylosuccinate synthetase/0.441
1rjeSAHLeucine carboxyl methyltransferase 12.1.1.2330.441
1w5sADPORC1-type DNA replication protein 2/0.441
1x1cSAHC-20 methyltransferase/0.441
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.441
1yw8A75Methionine aminopeptidase 2/0.441
2dxdANPNucleoside diphosphate kinase2.7.4.60.441
2e16SAHDiphthine synthase/0.441
2g20L1ARenin3.4.23.150.441
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.441
2i4qUA4Renin3.4.23.150.441
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.441
2x8hFADThioredoxin glutathione reductase/0.441
2xugTZ4Acetylcholinesterase3.1.1.70.441
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.441
3c1kT15Prothrombin3.4.21.50.441
3d4pNADL-lactate dehydrogenase 11.1.1.270.441
3dm6757Beta-secretase 13.4.23.460.441
3gviADPMalate dehydrogenase/0.441
3ieuGDPGTPase Era/0.441
3ik6HCZGlutamate receptor 2/0.441
3lsiFADPyranose 2-oxidase/0.441
3n14FMNXenobiotic reductase/0.441
3otwCOAPhosphopantetheine adenylyltransferase/0.441
3p84FMNPentaerythritol tetranitrate reductase/0.441
3phjDHKShikimate dehydrogenase (NADP(+))/0.441
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.441
3rk1ATPN-type ATP pyrophosphatase superfamily/0.441
3wagTYDGlycosyltransferase/0.441
4baoMVFProthrombin3.4.21.50.441
4btu6XSCoagulation factor X3.4.21.60.441
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.441
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.441
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4i1c1BEBeta-secretase 13.4.23.460.441
4imfSI3N-acetylneuraminate lyase/0.441
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4xo7NAPAldo-keto reductase family 1 member C2/0.441
4zwmPLPOrnithine aminotransferase, mitochondrial, putative/0.441
3vw7VPXProteinase-activated receptor 1/0.441
1em6CP4Glycogen phosphorylase, liver form2.4.1.10.440
1gky5GPGuanylate kinase2.7.4.80.440
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1nvmNADAcetaldehyde dehydrogenase1.2.1.100.440
1obbNADAlpha-glucosidase3.2.1.200.440
1u7hNADPutative ornithine cyclodeaminase/0.440
1vyrFMNPentaerythritol tetranitrate reductase/0.440
2dv7SAHDiphthine synthase/0.440
2eldSAHDiphthine synthase/0.440
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.440
2huxSAHDiphthine synthase/0.440
2ibzUQ6Cytochrome b/0.440
2jgsBTNAvidin/0.440
2npxNADNADH peroxidase1.11.1.10.440
2ph6712Beta-secretase 13.4.23.460.440
2uuj896Prothrombin3.4.21.50.440
2watCOAFatty acid synthase subunit alpha2.3.1.860.440
2ylxFADPhenylacetone monooxygenase1.14.13.920.440
2zhf49UProthrombin3.4.21.50.440
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.440
3gegNADShort-chain dehydrogenase/reductase SDR/0.440
3h3t16HCollagen type IV alpha-3-binding protein/0.440
3hl4CDCCholine-phosphate cytidylyltransferase A/0.440
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3lsmSFDPyranose 2-oxidase/0.440
3qvrFADGlucose oxidase1.1.3.40.440
4b3aTACTetracycline repressor protein class D/0.440
4bf9FMNtRNA-dihydrouridine(16) synthase/0.440
4ha9NDP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase1.1.1.3020.440
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.440
4rww2BALmo2692 protein/0.440
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
5agaANPDNA polymerase theta/0.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440
5irnADPNucleotide binding oligomerization domain containing 2/0.440