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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/1.000
2henADPEphrin type-B receptor 22.7.10.10.555
3c4wATPRhodopsin kinase/0.536
2qoqANPEphrin type-A receptor 32.7.10.10.533
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.530
3qc9ADPRhodopsin kinase/0.520
2ijmATPFocal adhesion kinase 12.7.10.20.518
2wqeADPAurora kinase A2.7.11.10.518
2qo7ANPEphrin type-A receptor 32.7.10.10.517
3c4zADPRhodopsin kinase/0.514
4l9i8PRRhodopsin kinase/0.511
4c3pACPAurora kinase A2.7.11.10.510
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.508
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.507
4gu94GUFocal adhesion kinase 12.7.10.20.506
4k8aK8AFocal adhesion kinase 12.7.10.20.504
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.503
4deeADPAurora kinase A2.7.11.10.503
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
2j0m4STFocal adhesion kinase 12.7.10.20.499
3c4xATPRhodopsin kinase/0.499
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.499
3t8oATPRhodopsin kinase/0.497
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.497
5l8lADPAurora kinase A2.7.11.10.497
4btjADPTau-tubulin kinase 12.7.11.10.496
2v7a627Tyrosine-protein kinase ABL12.7.10.20.494
2qo9ANPEphrin type-A receptor 32.7.10.10.493
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.492
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.492
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.492
1u54ACPActivated CDC42 kinase 1/0.491
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.491
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.490
2j0lANPFocal adhesion kinase 12.7.10.20.489
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.489
3my5RFZCyclin-dependent kinase 22.7.11.220.488
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.486
2w1fL0FAurora kinase A2.7.11.10.486
4qmlANPSerine/threonine-protein kinase 242.7.11.10.486
4qnyANPMitogen activated protein kinase, putative/0.486
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.486
5dt3ATPAurora kinase A2.7.11.10.486
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.485
2py3ACPFibroblast growth factor receptor 2/0.485
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.485
5dosATPAurora kinase A2.7.11.10.485
4k33ACPFibroblast growth factor receptor 32.7.10.10.484
1i44ACPInsulin receptor2.7.10.10.483
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.483
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.483
4xw5ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
5dnrATPAurora kinase A2.7.11.10.483
1ir3ANPInsulin receptor2.7.10.10.482
2yxuATPPyridoxal kinase2.7.1.350.482
3i60E86Mitogen-activated protein kinase 12.7.11.240.482
3nszANPCasein kinase II subunit alpha2.7.11.10.482
4lrjANPUncharacterized protein/0.481
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.481
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.479
4jrnANPRhoptry kinase family protein/0.479
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.478
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.478
4gk3L87Ephrin type-A receptor 32.7.10.10.477
3ztxZTXAurora kinase B-A2.7.11.10.476
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.476
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.475
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.475
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.475
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.474
4fvqATPTyrosine-protein kinase JAK2/0.474
1pdhFASp-hydroxybenzoate hydroxylase/0.473
4ii5ADPCyclin-dependent kinase 22.7.11.220.473
2c6eHPMAurora kinase A2.7.11.10.472
3a7hATPSerine/threonine-protein kinase 242.7.11.10.472
4eooATPCyclin-dependent kinase 22.7.11.220.472
5dn3ATPAurora kinase A2.7.11.10.472
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.471
3oriAGSSerine/threonine protein kinase/0.471
3gu7ADPDeath-associated protein kinase 12.7.11.10.470
4btjATPTau-tubulin kinase 12.7.11.10.470
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.470
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.469
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.469
3c50ADPRhodopsin kinase/0.469
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.469
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.469
4nmdFDABifunctional protein PutA/0.469
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
5i4nATPTyrosine-protein kinase JAK2/0.468
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.467
2qocANPEphrin type-A receptor 32.7.10.10.467
1jqhANPInsulin-like growth factor 1 receptor2.7.10.10.466
1ol7ADPAurora kinase A2.7.11.10.466
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.466
2cjmATPCyclin-dependent kinase 22.7.11.220.466
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4xlvACPInsulin receptor2.7.10.10.466
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.465
3pxkPXKFocal adhesion kinase 12.7.10.20.465
3tdwGDPGentamicin resistance protein/0.465
4jia1K3Tyrosine-protein kinase JAK2/0.465
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.465
4o0uADNAurora kinase A2.7.11.10.465
4ysjADPCalmodulin-like domain protein kinase/0.465
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.465
2xuuADPDeath-associated protein kinase 12.7.11.10.464
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.464
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
1l8qADPChromosomal replication initiator protein DnaA/0.463
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.463
2xs0ANPMitogen-activated protein kinase 82.7.11.240.463
3p8zSAHGenome polyprotein2.1.1.560.463
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.463
4z34ON7Lysophosphatidic acid receptor 1/0.463
1mqbANPEphrin type-A receptor 22.7.10.10.462
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.462
2bmcMPYAurora kinase A2.7.11.10.462
2fj1CTCTetracycline repressor protein class D/0.462
2ojj82AMitogen-activated protein kinase 12.7.11.240.462
4b8lA0PAurora kinase B-A2.7.11.10.462
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.462
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.462
5dpvSKEAurora kinase A2.7.11.10.462
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.461
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3vs3VSETyrosine-protein kinase HCK2.7.10.20.461
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4cd0AWJALK tyrosine kinase receptor2.7.10.10.461
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.461
4h9tHL4Phosphotriesterase/0.461
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.460
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.460
2y3rTRKTamL/0.460
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.460
1ci0FMNPyridoxamine 5'-phosphate oxidase1.4.3.50.459
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.459
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.459
2cy0NAPShikimate dehydrogenase (NADP(+))/0.459
2jn3JN3Fatty acid-binding protein, liver/0.459
2p2fCOAAcetyl-coenzyme A synthetase/0.459
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.459
2vwu7X1Ephrin type-B receptor 42.7.10.10.459
3junAJDPhenazine biosynthesis protein A/B/0.459
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.459
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.459
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.459
3ge1ADPGlycerol kinase/0.458
3iok1P6Tyrosine-protein kinase JAK2/0.458
3kvxFMYMitogen-activated protein kinase 102.7.11.240.458
3lu7IPXSerum albumin/0.458
4o1pANPRibonuclease L/0.458
5l8jADPAurora kinase A2.7.11.10.458
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.457
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.457
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1g4tFTPThiamine-phosphate synthase/0.456
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.456
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.456
3repATPIntegrin-linked protein kinase2.7.11.10.456
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.456
4bcmT7ZCyclin-dependent kinase 22.7.11.220.456
4gncASORegucalcin3.1.1.170.456
4j95ACPFibroblast growth factor receptor 2/0.456
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2etrY27Rho-associated protein kinase 12.7.11.10.455
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.455
2puiADPMethylthioribose kinase2.7.1.1000.455
2vkeTACTetracycline repressor protein class D/0.455
2y3sTIRTamL/0.455
3juqAJDPhenazine biosynthesis protein A/B/0.455
3ncz3NCRho-associated protein kinase 12.7.11.10.455
3orkAGSSerine/threonine protein kinase/0.455
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.455
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4k28NADShikimate dehydrogenase family protein/0.455
5cvhADPCasein kinase II subunit alpha2.7.11.10.455
5e92ANPTGF-beta receptor type-22.7.11.300.455
5iqiGNPBifunctional AAC/APH2.3.10.455
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.454
1kquBR4Phospholipase A2, membrane associated/0.454
2hog710Serine/threonine-protein kinase Chk12.7.11.10.454
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.454
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3zewSTUEphrin type-B receptor 42.7.10.10.454
4g2fC07Ephrin type-A receptor 32.7.10.10.454
4i6gFADCryptochrome-2/0.454
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.453
2acxANPG protein-coupled receptor kinase 62.7.11.160.453
2pdtFADVivid PAS protein VVD/0.453
2xneASHAurora kinase A2.7.11.10.453
3clyACPFibroblast growth factor receptor 2/0.453
3w16P9JAurora kinase A2.7.11.10.453
4f6w0SSCyclin-dependent kinase 82.7.11.220.453
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
5dbgNADIridoid synthase1.3.1.990.453
1hdrNADDihydropteridine reductase1.5.1.340.452
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.452
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.452
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.452
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.452
4fv6E57Mitogen-activated protein kinase 12.7.11.240.452
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.452
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4ly91YYGlucokinase regulatory protein/0.452
1cm8ANPMitogen-activated protein kinase 12/0.451
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1qmzATPCyclin-dependent kinase 22.7.11.220.451
1u28NADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.451
3pe2E1BCasein kinase II subunit alpha2.7.11.10.451
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.451
3w1rMRODihydroorotate dehydrogenase (fumarate)1.3.98.10.451
4b8zGDPGDP-L-fucose synthase1.1.1.2710.451
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.451
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
5e8ySTUTGF-beta receptor type-22.7.11.300.451
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.450
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2vgpAD6Aurora kinase B-A2.7.11.10.450
2xgoZKDUncharacterized protein/0.450
3cvuFADRE11660p/0.450
3s1dZIRCytokinin dehydrogenase 11.5.99.120.450
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.450
4j99ACPFibroblast growth factor receptor 2/0.450
4lfiGNPCasein kinase II subunit alpha2.7.11.10.450
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.450
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.450
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
1w06W05Isopenicillin N synthase1.21.3.10.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2ojg19AMitogen-activated protein kinase 12.7.11.240.449
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.449
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.449
3icsADPCoenzyme A disulfide reductase/0.449
3p8jFMNPentaerythritol tetranitrate reductase/0.449
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.449
4fob0USALK tyrosine kinase receptor2.7.10.10.449
4i3zADPCyclin-dependent kinase 22.7.11.220.449
4mv4ACPBiotin carboxylase6.3.4.140.449
4z69DIFSerum albumin/0.449
5aaaVGHALK tyrosine kinase receptor2.7.10.10.449
1jkkANPDeath-associated protein kinase 12.7.11.10.448
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.448
1ol5ADPAurora kinase A2.7.11.10.448
1rkxNADCDP-D-glucose-4,6-dehydratase/0.448
1u80C5PCoenzyme A biosynthesis bifunctional protein CoaBC6.3.2.50.448
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.448
2x9fX9FEphrin type-B receptor 42.7.10.10.448
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.448
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3eljGS7Mitogen-activated protein kinase 82.7.11.240.448
3m31FADEndoplasmic oxidoreductin-11.8.40.448
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.448
4hyu1BKMitogen-activated protein kinase 82.7.11.240.448
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.448
4jqeANPCasein kinase II subunit alpha2.7.11.10.448
4oauADP2-5A-dependent ribonuclease3.1.260.448
5drdATPAurora kinase A2.7.11.10.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
2bfyH1NAurora kinase B-A2.7.11.10.447
2j50627Aurora kinase A2.7.11.10.447
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.447
2vrx447Aurora kinase B-A2.7.11.10.447
3a8wATPProtein kinase C iota type2.7.11.130.447
3e39FMNNitroreductase/0.447
3juqAKDPhenazine biosynthesis protein A/B/0.447
3k5uPFQAurora kinase A2.7.11.10.447
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.447
3w2uROUDihydroorotate dehydrogenase (fumarate)1.3.98.10.447
3zcxNADGlyceraldehyde-3-phosphate dehydrogenase/0.447
4cukNAID-lactate dehydrogenase/0.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.447
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
5eg3ACPFibroblast growth factor receptor 2/0.447
1g69TZPThiamine-phosphate synthase/0.446
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.446
1jnkANPMitogen-activated protein kinase 102.7.11.240.446
2an9GDPGuanylate kinase2.7.4.80.446
2izsBRQCasein kinase I isoform gamma-32.7.11.10.446
2w4kADPDeath-associated protein kinase 12.7.11.10.446
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.446
3cgcFADCoenzyme A disulfide reductase/0.446
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4s33ANPMitogen-activated protein kinase 12.7.11.240.446
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.446
1j39UPGDNA beta-glucosyltransferase/0.445
1o9bNAIQuinate/shikimate dehydrogenase/0.445
1qxoFMNChorismate synthase/0.445
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.445
2c6dANPAurora kinase A2.7.11.10.445
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.445
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2xrwANPMitogen-activated protein kinase 82.7.11.240.445
3lpbNVBTyrosine-protein kinase JAK2/0.445
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.445
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.445
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.445
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.445
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.445
4g1wG1WMitogen-activated protein kinase 82.7.11.240.445
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.445
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.445
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
2w4jADPDeath-associated protein kinase 12.7.11.10.444
3h86AP5Adenylate kinase/0.444
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.444
3tm5SFGUncharacterized protein/0.444
3zlmANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.444
4g8jTHMUridine phosphorylase/0.444
4i8vBHFCytochrome P450 1A11.14.14.10.444
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.444
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.444
4ztvTA7Anthranilate phosphoribosyltransferase/0.444
5dr2ATPAurora kinase A2.7.11.10.444
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.443
1qtmTTPDNA polymerase I, thermostable2.7.7.70.443
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.443
2j9gADPBiotin carboxylase6.3.4.140.443
2p33J07Mitogen-activated protein kinase 102.7.11.240.443
2uzbC75Cyclin-dependent kinase 22.7.11.220.443
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.443
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.443
3evaSAHGenome polyprotein2.1.1.560.443
3fhxPXLPyridoxal kinase2.7.1.350.443
3plsANPMacrophage-stimulating protein receptor2.7.10.10.443
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.443
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.443
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.443
4ccbOFGALK tyrosine kinase receptor2.7.10.10.443
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.443
4fv9E71Mitogen-activated protein kinase 12.7.11.240.443
1csnATPCasein kinase I homolog 12.7.11.10.442
1ewyFADFerredoxin--NADP reductase1.18.1.20.442
1vbiNADMalate/L-lactate dehydrogenase family protein/0.442
1zeoC01Peroxisome proliferator-activated receptor gamma/0.442
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2pd7FADVivid PAS protein VVD/0.442
2rghFADAlpha-Glycerophosphate Oxidase/0.442
2x6dX6DAurora kinase A2.7.11.10.442
3dds26BGlycogen phosphorylase, liver form2.4.1.10.442
3gcuR48Mitogen-activated protein kinase 14/0.442
3orpAGSSerine/threonine protein kinase/0.442
3tdvGDPGentamicin resistance protein/0.442
3u9eCOALmo1369 protein/0.442
3zl8ADPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.442
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4bl5GFBGDP-L-fucose synthase1.1.1.2710.442
4c3yANB3-ketosteroid dehydrogenase/0.442
4c57FEFCyclin-G-associated kinase2.7.11.10.442
4dpmCOAMalonyl-CoA reductase1.2.1.750.442
4dpy2P0Mevalonate diphosphate decarboxylase/0.442
4hvh19RTyrosine-protein kinase JAK32.7.10.20.442
4j97ACPFibroblast growth factor receptor 2/0.442
4jajXU1Aurora kinase A2.7.11.10.442
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.442
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.442
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.441
1yvj4STTyrosine-protein kinase JAK32.7.10.20.441
2cciATPCyclin-dependent kinase 22.7.11.220.441
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.441
2itqITQEpidermal growth factor receptor2.7.10.10.441
2rhrEMOPutative ketoacyl reductase1.3.10.441
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2vprTDCTetracycline repressor protein class H/0.441
2xvw9NRSerum albumin/0.441
2yx6ADPUncharacterized protein/0.441
3eem53VUncharacterized protein/0.441
3g51ANPRibosomal protein S6 kinase alpha-32.7.11.10.441
3g8dADPBiotin carboxylase6.3.4.140.441
3lu6IMXSerum albumin/0.441
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
4b99R4LMitogen-activated protein kinase 72.7.11.240.441
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.441
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.441
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.441
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.441
5aacVGHALK tyrosine kinase receptor2.7.10.10.441
1i5aACPChemotaxis protein CheA2.7.13.30.440
1ig1ANPDeath-associated protein kinase 12.7.11.10.440
1nvtNAPShikimate dehydrogenase (NADP(+))/0.440
1ol6ATPAurora kinase A2.7.11.10.440
1ztfXYARIO-type serine/threonine-protein kinase Rio12.7.11.10.440
2j4z626Aurora kinase A2.7.11.10.440
2o2u738Mitogen-activated protein kinase 102.7.11.240.440
2vgoAD5Aurora kinase B-A2.7.11.10.440
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.440
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.440
3eej53RUncharacterized protein/0.440
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3tr05GPGuanylate kinase/0.440
3vtdTKDVitamin D3 receptor/0.440
4c58824Cyclin-G-associated kinase2.7.11.10.440
4cegADPAurora kinase A2.7.11.10.440
4dpwAGSMevalonate diphosphate decarboxylase/0.440
4l4cCAMCamphor 5-monooxygenase1.14.15.10.440
4nmbFADBifunctional protein PutA/0.440
4q71FADBifunctional protein PutA/0.440
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.440