sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	1.000
1f17	NAI	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.608
2hdh	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.589
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.566
3had	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.542
1lso	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.537
4kug	NAD	3-hydroxybutyryl-CoA dehydrogenase	/	0.490
4kuh	CAA	3-hydroxybutyryl-CoA dehydrogenase	/	0.490
1f12	3HC	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.451