sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3h3f	NAI	L-lactate dehydrogenase A chain	1.1.1.27

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3h3f	NAI	L-lactate dehydrogenase A chain	1.1.1.27	1.000
4l4s	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.535
4rls	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.526
4i8x	6P3	L-lactate dehydrogenase A chain	1.1.1.27	0.521
4jnk	NAI	L-lactate dehydrogenase A chain	1.1.1.27	0.492
1hyg	NAP	L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))	/	0.489
3zzn	ADP	L-lactate dehydrogenase	/	0.479
3pqf	NAD	L-lactate dehydrogenase	1.1.1.27	0.469
4i9h	1E4	L-lactate dehydrogenase A chain	1.1.1.27	0.454
2a92	NAI	L-lactate dehydrogenase	/	0.452
3gvi	ADP	Malate dehydrogenase	/	0.448
1bdm	NAX	Malate dehydrogenase	/	0.440