sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 1.000 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.653 | |
| 3up0 | D7S | aceDAF-12 | / | 0.551 | |
| 3up3 | XCA | aceDAF-12 | / | 0.522 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.477 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.456 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.440 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.440 |