sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3gka	FMN	N-ethylmaleimide reductase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3gka	FMN	N-ethylmaleimide reductase	/	1.000
4jic	FMN	GTN Reductase	/	0.501
3f03	FMN	Pentaerythritol tetranitrate reductase	/	0.475
4tmb	FMN	Old yellow enzyme	/	0.474
1h50	FMN	Pentaerythritol tetranitrate reductase	/	0.472
1icp	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.470
2abb	FMN	Pentaerythritol tetranitrate reductase	/	0.462
1vyr	FMN	Pentaerythritol tetranitrate reductase	/	0.457
1h63	FMN	Pentaerythritol tetranitrate reductase	/	0.456
1ics	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.455
4a3u	FMN	NADH:flavin oxidoreductase/NADH oxidase	/	0.455
1icq	FMN	12-oxophytodienoate reductase 1	1.3.1.42	0.447
3p62	FMN	Pentaerythritol tetranitrate reductase	/	0.446
3p82	FMN	Pentaerythritol tetranitrate reductase	/	0.442
3p74	FMN	Pentaerythritol tetranitrate reductase	/	0.441