sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3g0g | RUM | Dipeptidyl peptidase 4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 1.000 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.779 | |
| 3g0d | XIH | Dipeptidyl peptidase 4 | / | 0.726 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.692 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.657 | |
| 4a5s | N7F | Dipeptidyl peptidase 4 | / | 0.628 | |
| 4g1f | 0WG | Dipeptidyl peptidase 4 | / | 0.628 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.576 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.552 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.522 | |
| 2rgu | 356 | Dipeptidyl peptidase 4 | / | 0.517 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.506 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.499 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.498 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.494 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.494 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.491 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.489 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.489 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.489 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.488 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.487 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.486 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.486 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.485 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.485 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.485 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.482 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.482 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.482 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.480 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.479 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.479 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.477 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.476 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.474 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.473 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.473 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.472 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.472 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.471 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.471 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.470 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.470 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.470 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.470 | |
| 4l4x | NDP | AmphI | / | 0.470 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.468 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.468 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.467 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.467 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.467 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.466 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.466 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.465 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.465 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.465 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.464 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.464 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.464 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.464 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.464 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.464 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.464 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.464 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.463 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.463 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.463 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.463 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.463 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.463 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.462 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.462 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.462 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.462 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.462 | |
| 4e32 | DWN | Methyltransferase | / | 0.462 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.462 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.460 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.460 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.460 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.460 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.460 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.459 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.459 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.459 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.459 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.459 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.459 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.459 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.459 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.459 | |
| 1zdw | FLV | Prenyltransferase | / | 0.458 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4lut | DCS | Alanine racemase | / | 0.458 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.457 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.457 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.457 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.457 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.457 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.457 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.457 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.457 | |
| 1jil | 485 | Tyrosine--tRNA ligase | / | 0.456 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.456 | |
| 1xgj | HTC | Beta-lactamase | 3.5.2.6 | 0.456 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.456 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.456 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.456 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.456 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.456 | |
| 1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.455 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.455 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.455 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.455 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3eks | CY9 | Actin-5C | / | 0.455 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.455 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.455 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.455 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.454 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.454 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
| 4ffw | 715 | Dipeptidyl peptidase 4 | / | 0.454 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.454 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.453 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.453 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.453 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.453 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.453 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.453 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.453 | |
| 3f6s | FMN | Flavodoxin | / | 0.453 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.453 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.453 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.453 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.453 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.453 | |
| 1e2n | RCA | Thymidine kinase | / | 0.452 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.452 | |
| 3bnk | FMN | Flavoredoxin | / | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.452 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.452 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.452 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.452 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.452 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.451 | |
| 1p4a | PCP | Pur operon repressor | / | 0.451 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.451 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.451 | |
| 3eku | CY9 | Actin-5C | / | 0.451 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.451 | |
| 4e2d | FMN | Dehydrogenase | / | 0.451 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 4gv8 | DUP | DUTPase | / | 0.451 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.451 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.450 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.450 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.450 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.450 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.449 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.449 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.449 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.449 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.449 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.449 | |
| 4e31 | JHZ | Methyltransferase | / | 0.449 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.449 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.449 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.448 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.448 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.448 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 2oae | AIL | Dipeptidyl peptidase 4 | / | 0.448 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.448 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.448 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.448 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.448 | |
| 4tm4 | FDA | KtzI | / | 0.448 | |
| 4xd1 | T3Q | Qdtf | / | 0.448 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 1n0s | FLU | Bilin-binding protein | / | 0.447 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.447 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.447 | |
| 2q9c | GNP | Signal recognition particle receptor FtsY | / | 0.447 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.447 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4rel | KMP | Glycosyltransferase | / | 0.447 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.447 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.447 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.446 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.446 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.446 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.446 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.446 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 4gtm | 7TM | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.446 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.446 | |
| 5c41 | ACP | Ribokinase | / | 0.446 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.445 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.445 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3hf3 | FMN | Chromate reductase | / | 0.445 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.445 | |
| 3ndj | JHZ | Methyltransferase | / | 0.445 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.445 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.445 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.445 | |
| 4j7h | TRH | PCZA361.3 | / | 0.445 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.444 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.444 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.444 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.444 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.444 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.444 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.444 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 1zny | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.443 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.443 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 2pcm | SAH | Diphthine synthase | / | 0.443 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.443 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.443 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.443 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.443 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.443 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.443 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.443 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.442 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.442 | |
| 2r8p | T6F | Transketolase 1 | / | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.442 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.442 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.442 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2w02 | ATP | AcsD | / | 0.441 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.441 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.441 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.441 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.441 | |
| 4tmn | 0PK | Thermolysin | 3.4.24.27 | 0.441 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.440 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.440 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.440 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.440 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.440 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3fgd | BYA | Thermolysin | 3.4.24.27 | 0.440 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.440 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.440 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.440 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.440 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 |