sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fv4 | 1U4 | Thermolysin | 3.4.24.27 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3fv4 | 1U4 | Thermolysin | 3.4.24.27 | 1.000 | |
| 3fvp | UB2 | Thermolysin | 3.4.24.27 | 0.631 | |
| 1qf2 | TI3 | Thermolysin | 3.4.24.27 | 0.626 | |
| 3f2p | S3B | Thermolysin | 3.4.24.27 | 0.586 | |
| 3t87 | UBZ | Thermolysin | 3.4.24.27 | 0.575 | |
| 3t8d | UBV | Thermolysin | 3.4.24.27 | 0.568 | |
| 4h57 | 0PJ | Thermolysin | 3.4.24.27 | 0.566 | |
| 1u4g | HPI | Elastase | 3.4.24.26 | 0.563 | |
| 2tmn | 0FA | Thermolysin | 3.4.24.27 | 0.562 | |
| 3for | ZNP | Thermolysin | 3.4.24.27 | 0.554 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.550 | |
| 3t8c | UBW | Thermolysin | 3.4.24.27 | 0.549 | |
| 3t8h | UBS | Thermolysin | 3.4.24.27 | 0.540 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.539 | |
| 4tmn | 0PK | Thermolysin | 3.4.24.27 | 0.519 | |
| 4e2b | FMN | Dehydrogenase | / | 0.518 | |
| 4d9w | X32 | Thermolysin | 3.4.24.27 | 0.517 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.516 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.509 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.509 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.509 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.507 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.506 | |
| 3fgd | BYA | Thermolysin | 3.4.24.27 | 0.506 | |
| 1n7h | GDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.505 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.505 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.505 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.502 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.499 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.497 | |
| 3c1o | NAP | Eugenol synthase | / | 0.497 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.497 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.496 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.496 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.496 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.495 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.493 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 4ck2 | NVU | Integrase | / | 0.492 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.487 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.487 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.487 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.487 | |
| 2qhw | PZZ | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.486 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.485 | |
| 2ohv | NHL | Glutamate racemase | / | 0.484 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.484 | |
| 3nhx | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.484 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.484 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.483 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 2imp | NAI | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.483 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.483 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.482 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.482 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.481 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.481 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.481 | |
| 4e09 | ACP | Plasmid partitioning protein ParF | / | 0.480 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.480 | |
| 1bxr | ANP | Carbamoyl-phosphate synthase large chain | / | 0.479 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.479 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.479 | |
| 4ojb | 198 | Androgen receptor | / | 0.479 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.478 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.477 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.477 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.477 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4okx | 198 | Androgen receptor | / | 0.477 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.477 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.477 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.476 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.476 | |
| 4hjf | C2E | GGDEF family protein | / | 0.476 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.475 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.475 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.475 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 4f7l | 0SO | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.475 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.475 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.475 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.474 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.474 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.474 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.474 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.473 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.473 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.473 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.473 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.473 | |
| 2y3r | TRK | TamL | / | 0.473 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.473 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.473 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.473 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.472 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.472 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.472 | |
| 4dqw | ATP | Inosine-5'-monophosphate dehydrogenase | / | 0.472 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.472 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.471 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.471 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.471 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.471 | |
| 1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.471 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.471 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.471 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.471 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.471 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.471 | |
| 4uoc | NCN | CinA-like protein | / | 0.471 | |
| 4xcz | FON | Qdtf | / | 0.471 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.470 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.470 | |
| 2e20 | B4P | Propionate kinase | / | 0.470 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.470 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.470 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.470 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.470 | |
| 4okb | 198 | Androgen receptor | / | 0.470 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.470 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.469 | |
| 1u30 | GOX | Pancreatic alpha-amylase | / | 0.469 | |
| 2olr | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.469 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.469 | |
| 2xuz | EB4 | Iron-uptake system-binding protein | / | 0.469 | |
| 3nf8 | CDQ | Gag-Pol polyprotein | / | 0.469 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.469 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.469 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.469 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.468 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.468 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.468 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.468 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 3eld | SFG | Methyltransferase | / | 0.468 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.468 | |
| 1bof | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.467 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1uak | SAM | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.467 | |
| 2uyi | ADP | Kinesin-like protein KIF11 | / | 0.467 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.467 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.467 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.467 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.467 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.467 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.467 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.467 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.467 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.467 | |
| 1drt | PCV | Clavaminate synthase 1 | 1.14.11.21 | 0.466 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.466 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.466 | |
| 3eku | CY9 | Actin-5C | / | 0.466 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 4jic | FMN | GTN Reductase | / | 0.466 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.465 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.465 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.465 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.465 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.465 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 4c35 | NU3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 4cfa | WOP | Integrase | / | 0.465 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.465 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.464 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.464 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1mdr | APG | Mandelate racemase | / | 0.464 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.464 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2e9z | UTP | Genome polyprotein | / | 0.464 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.464 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.464 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.464 | |
| 2trs | PLS | Tryptophan synthase beta chain | 4.2.1.20 | 0.464 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.464 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.464 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.464 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.464 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.464 | |
| 1nmd | ATP | Major actin | / | 0.463 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.463 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.463 | |
| 2ewv | ADP | Twitching motility protein PilT | / | 0.463 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.463 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.463 | |
| 3fd6 | ADP | Selenide, water dikinase 1 | 2.7.9.3 | 0.463 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.463 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.463 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.463 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.463 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.463 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.463 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.462 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.462 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.462 | |
| 1xje | GDP | Vitamin B12-dependent ribonucleotide reductase | / | 0.462 | |
| 1ytm | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.462 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.462 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.462 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.462 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 4hc4 | SAH | Protein arginine N-methyltransferase 6 | / | 0.462 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 2xvq | 9DS | Serum albumin | / | 0.461 | |
| 2xw1 | 9NV | Serum albumin | / | 0.461 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.461 | |
| 3o3p | GDD | Glycosyl transferase, family 2 | / | 0.461 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.461 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 3zt2 | ZT2 | Integrase | / | 0.461 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4ck1 | OM1 | Integrase | / | 0.461 | |
| 4e2d | FMN | Dehydrogenase | / | 0.461 | |
| 4ehu | ANP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.461 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.461 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.461 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.460 | |
| 1stp | BTN | Streptavidin | / | 0.460 | |
| 1ual | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.460 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.460 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 2bxq | IMN | Serum albumin | / | 0.460 | |
| 2e77 | FMN | Lactate oxidase | / | 0.460 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.460 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.460 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.460 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.460 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.460 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 3w1r | MRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.460 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.460 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.460 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.460 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.460 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.460 | |
| 4jey | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.460 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.460 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.460 | |
| 1ank | ANP | Adenylate kinase | / | 0.459 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.459 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.459 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.459 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.459 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.459 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1za1 | CTP | Aspartate carbamoyltransferase regulatory chain | / | 0.459 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.459 | |
| 2h23 | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.459 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.459 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 3rdo | BTN | Streptavidin | / | 0.459 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.459 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.459 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.459 | |
| 5a02 | NAP | Glucose-fructose oxidoreductase | / | 0.459 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.458 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.458 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.458 | |
| 1ovm | TPP | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.458 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.458 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.458 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.458 | |
| 2prz | OMP | Orotate phosphoribosyltransferase 1 | 2.4.2.10 | 0.458 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.458 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.458 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.458 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.458 | |
| 4xrq | 1B0 | Gag polyprotein | / | 0.458 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.457 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.457 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.457 | |
| 1g6c | IFP | Thiamine-phosphate synthase | / | 0.457 | |
| 1nd5 | 2BF | Prostatic acid phosphatase | 3.1.3.2 | 0.457 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.457 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.457 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.457 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.457 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.457 | |
| 2qfv | NAP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.457 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
| 2z0x | 5CA | Uncharacterized protein | / | 0.457 | |
| 2zfa | FMN | Lactate oxidase | / | 0.457 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.457 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.457 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.457 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.457 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 4fvr | ATP | Tyrosine-protein kinase JAK2 | / | 0.457 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.457 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.457 | |
| 1b4p | GPS | Glutathione S-transferase Mu 2 | / | 0.456 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.456 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.456 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.456 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.456 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.456 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 2wzg | UPG | Uncharacterized protein | / | 0.456 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.456 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.456 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.456 | |
| 4koa | NDP | 1,5-anhydro-D-fructose reductase | 1.1.1.292 | 0.456 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.456 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.456 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.456 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.456 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.456 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.455 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.455 | |
| 1zcb | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.455 | |
| 2du2 | FMN | Lactate oxidase | / | 0.455 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.455 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.455 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 2zr9 | DTP | Protein RecA | / | 0.455 | |
| 3dt4 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.455 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.455 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.455 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3kme | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.455 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.455 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.455 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.455 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.455 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.455 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 3zrc | L8B | Von Hippel-Lindau disease tumor suppressor | / | 0.455 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.455 | |
| 4cgg | K5Q | Integrase | / | 0.455 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.455 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.455 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.455 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.455 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.454 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.454 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.454 | |
| 1jut | LYD | Thymidylate synthase | / | 0.454 | |
| 1nsy | ATP | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.454 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.454 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.454 | |
| 2emu | SAH | Diphthine synthase | / | 0.454 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.454 | |
| 2i14 | PCP | Nicotinate-nucleotide pyrophosphorylase | / | 0.454 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.454 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.454 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2xvw | 9NR | Serum albumin | / | 0.454 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.454 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.454 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.454 | |
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.454 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.454 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.454 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 3smk | CW7 | 14-3-3 protein sigma | / | 0.454 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.454 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.454 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.454 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.454 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.454 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.454 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 4nt0 | 3DU | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.454 | |
| 4okt | 198 | Androgen receptor | / | 0.454 | |
| 4zo3 | C6L | Acylhomoserine lactonase | / | 0.454 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.454 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.454 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1mc1 | PCX | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.453 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 1wbt | WBT | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.453 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.453 | |
| 2dsg | SAH | Diphthine synthase | / | 0.453 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.453 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.453 | |
| 2jfz | 003 | Glutamate racemase | / | 0.453 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.453 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.453 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.453 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.453 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.453 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.453 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.453 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.453 | |
| 3vax | PLP | Uncharacterized protein | / | 0.453 | |
| 3zsx | N44 | Integrase | / | 0.453 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4do0 | DZA | Histone lysine demethylase PHF8 | 1.14.11.27 | 0.453 | |
| 4hwk | SFY | Sepiapterin reductase | 1.1.1.153 | 0.453 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.453 | |
| 4yqf | GDP | Septin-9 | / | 0.453 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.452 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.452 | |
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.452 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.452 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.452 | |
| 1vce | SAH | Diphthine synthase | / | 0.452 | |
| 1z6p | 194 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.452 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 2wgh | DTP | Ribonucleoside-diphosphate reductase large subunit | 1.17.4.1 | 0.452 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.452 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.452 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.452 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.452 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.452 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.452 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.452 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.452 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.452 | |
| 3zsw | ZSW | Integrase | / | 0.452 | |
| 4cgh | LOZ | Integrase | / | 0.452 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4olm | 198 | Androgen receptor | / | 0.452 | |
| 4rwt | ANP | Actin-5C | / | 0.452 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.452 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.452 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.452 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.451 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.451 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.451 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.451 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.451 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.451 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 2bp1 | NDP | Aflatoxin B1 aldehyde reductase member 2 | / | 0.451 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.451 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.451 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.451 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.451 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.451 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.451 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.451 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.451 | |
| 3zt1 | OM1 | Integrase | / | 0.451 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.451 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.451 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.451 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4o1p | ANP | Ribonuclease L | / | 0.451 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.451 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.451 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.451 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.450 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.450 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.450 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1nqm | BTN | Streptavidin | / | 0.450 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.450 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2ahc | VNL | Chorismate pyruvate-lyase | / | 0.450 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.450 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.450 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.450 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.450 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.450 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.450 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.450 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.450 | |
| 3zdg | XRX | Acetylcholine-binding protein | / | 0.450 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
| 4fw4 | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.450 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4xvr | GNP | GTPase HRas | / | 0.450 | |
| 4ys2 | 2BA | Uncharacterized protein | / | 0.450 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.449 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.449 | |
| 1pw6 | FRB | Interleukin-2 | / | 0.449 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.449 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.449 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
| 2amb | 17H | Androgen receptor | / | 0.449 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.449 | |
| 2eft | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.449 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.449 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.449 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.449 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.449 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.449 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3o2x | 3O2 | Collagenase 3 | 3.4.24 | 0.449 | |
| 3v2u | ATP | Protein GAL3 | / | 0.449 | |
| 3zcm | PX3 | Integrase | / | 0.449 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.449 | |
| 4cjw | CBJ | Integrase | / | 0.449 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.449 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.449 | |
| 4okw | 198 | Androgen receptor | / | 0.449 | |
| 4rel | KMP | Glycosyltransferase | / | 0.449 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4xw5 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.448 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 1mra | APG | Mandelate racemase | / | 0.448 | |
| 1p9p | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.448 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2apc | UDM | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2hl3 | GLU_GLU_TYR | Dynactin subunit 1 | / | 0.448 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.448 | |
| 2p3q | SAH | Genome polyprotein | / | 0.448 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.448 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.448 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.448 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.448 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.448 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3h5u | H5U | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.448 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3oog | YTP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.448 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.448 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.448 | |
| 3v49 | PK0 | Androgen receptor | / | 0.448 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4bmp | FMN | Protein NrdI | / | 0.448 | |
| 4f09 | JAK | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.448 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.448 | |
| 4h6p | FMN | Chromate reductase | / | 0.448 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.448 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.448 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.448 | |
| 5il1 | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.448 | |
| 1axw | MTX | Thymidylate synthase | / | 0.447 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 1g69 | TZP | Thiamine-phosphate synthase | / | 0.447 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.447 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.447 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.447 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.447 | |
| 1uay | ADN | Oxidoreductase | / | 0.447 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.447 | |
| 1z95 | 198 | Androgen receptor | / | 0.447 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.447 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.447 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.447 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2v18 | FMN | Dodecin | / | 0.447 | |
| 2y4g | TIR | TamL | / | 0.447 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.447 | |
| 3ahi | HTL | Probable phosphoketolase | / | 0.447 | |
| 3cnp | SP7 | Polyamine oxidase FMS1 | / | 0.447 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.447 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.447 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4ahv | Z5P | Gag-Pol polyprotein | / | 0.447 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.447 | |
| 4cf1 | IY7 | Integrase | / | 0.447 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.447 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.447 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.447 | |
| 4n1g | CEI | Obelin | / | 0.447 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.447 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.446 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.446 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.446 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 1sdm | ADP | Kinesin heavy chain-like protein | / | 0.446 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.446 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.446 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.446 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.446 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.446 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.446 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.446 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3bnk | FMN | Flavoredoxin | / | 0.446 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3kbz | 2T4 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.446 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.446 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.446 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.446 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.446 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3rdq | DTB | Streptavidin | / | 0.446 | |
| 3wti | CT4 | Acetylcholine-binding protein | / | 0.446 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.446 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.446 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.446 | |
| 4j21 | AJ6 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4j7d | I31 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.446 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.446 | |
| 4nu0 | AP5 | Adenylate kinase | / | 0.446 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.446 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.446 | |
| 4x3m | ADN | RNA 2'-O ribose methyltransferase | / | 0.446 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.446 | |
| 5a3b | APR | SIR2 family protein | / | 0.446 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.446 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.445 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.445 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.445 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.445 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.445 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 1qy5 | NEC | Endoplasmin | / | 0.445 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.445 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.445 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2e8q | SAH | Diphthine synthase | / | 0.445 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.445 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2nli | FMN | Lactate oxidase | / | 0.445 | |
| 2qe5 | 617 | Polyprotein | / | 0.445 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.445 | |
| 2w8r | ADP | Succinate-semialdehyde dehydrogenase, mitochondrial | 1.2.1.24 | 0.445 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3elu | SAM | Methyltransferase | / | 0.445 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.445 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3kr8 | XAV | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.445 | |
| 3n0z | 3AT | Adenylate cyclase 2 | / | 0.445 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.445 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.445 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.445 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.445 | |
| 3vqd | MOK | POL polyprotein | / | 0.445 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.445 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4j7h | TRH | PCZA361.3 | / | 0.445 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.445 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.445 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.445 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.445 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.445 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.445 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.444 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.444 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.444 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.444 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.444 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.444 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.444 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.444 | |
| 2bun | FAD | AppA protein | / | 0.444 | |
| 2cdu | FAD | NADH oxidase | / | 0.444 | |
| 2emr | SAH | Diphthine synthase | / | 0.444 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2hdn | TAC | Elongation factor Tu 1 | / | 0.444 | |
| 2kce | D16 | Thymidylate synthase | / | 0.444 | |
| 2r4f | RIE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.444 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 2w2v | GTP | Ras-related C3 botulinum toxin substrate 2 | / | 0.444 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.444 | |
| 2xau | ADP | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 | 3.6.4.13 | 0.444 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.444 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 3fgo | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.444 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4cer | VL4 | Integrase | / | 0.444 | |
| 4cj4 | S3G | Integrase | / | 0.444 | |
| 4fiv | LP1 | POL protein | / | 0.444 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.444 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.444 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.444 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.444 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.444 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.444 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.444 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.444 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.444 | |
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 0.444 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.444 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.444 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.443 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.443 | |
| 1hk4 | T44 | Serum albumin | / | 0.443 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.443 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.443 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.443 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.443 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.443 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.443 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.443 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.443 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2jir | MGD | Periplasmic nitrate reductase | / | 0.443 | |
| 2pda | TPP | Pyruvate synthase | / | 0.443 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.443 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3dlp | 174 | 4-chlorobenzoyl CoA ligase | / | 0.443 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.443 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.443 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.443 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3uf7 | ASP_ILE_PRO_PHE | Uracil-DNA glycosylase | 3.2.2.27 | 0.443 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.443 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.443 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 4bmo | FMN | Protein NrdI | / | 0.443 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4ceo | G0T | Integrase | / | 0.443 | |
| 4f6s | 0SQ | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.443 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.443 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.443 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.443 | |
| 4w6z | 8ID | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.443 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.443 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.443 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5fv0 | ONA | ESX secretion system protein EccC | / | 0.443 | |
| 1ake | AP5 | Adenylate kinase | / | 0.442 | |
| 1ej2 | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.442 | |
| 1esq | TZP | Hydroxyethylthiazole kinase | / | 0.442 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.442 | |
| 1uum | FMN | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.442 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.442 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.442 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.442 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.442 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.442 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 0.442 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3oxk | 5GP | Histidine triad nucleotide-binding protein | 3 | 0.442 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.442 | |
| 3u2x | ASO | Glycogenin-1 | 2.4.1.186 | 0.442 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3wip | ACH | Acetylcholine-binding protein | / | 0.442 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4cfb | OM3 | Integrase | / | 0.442 | |
| 4d96 | 5PA | D-cysteine desulfhydrase | / | 0.442 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.442 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.442 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.442 | |
| 4kh0 | ATP | Aspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002} | / | 0.442 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.442 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 4nvk | 2NY | Peroxidase | / | 0.442 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.442 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.441 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.441 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.441 | |
| 1efa | NPF | Lactose operon repressor | / | 0.441 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.441 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.441 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.441 | |
| 1p3j | AP5 | Adenylate kinase | / | 0.441 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.441 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.441 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1z7e | UGA | Bifunctional polymyxin resistance protein ArnA | / | 0.441 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2aia | SB8 | Peptide deformylase | / | 0.441 | |
| 2ejz | SAH | Diphthine synthase | / | 0.441 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.441 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2rkg | AB1 | Pol protein | / | 0.441 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.441 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.441 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.441 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3ewy | U5P | Uridine 5'-monophosphate synthase | 4.1.1.23 | 0.441 | |
| 3g9n | J88 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3l05 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.441 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3mje | NDP | AmphB | / | 0.441 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.441 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4b1f | KRH | Glutamate racemase | / | 0.441 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.441 | |
| 4dkp | 0LL | Envelope glycoprotein gp160 | / | 0.441 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.441 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.441 | |
| 4l4x | NDP | AmphI | / | 0.441 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4v02 | ATP | Site-determining protein | / | 0.441 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.441 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.441 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.440 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.440 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.440 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.440 | |
| 1ngd | ADP | Heat shock cognate 71 kDa protein | / | 0.440 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.440 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.440 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1s4e | ADP | Galactokinase | / | 0.440 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.440 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.440 | |
| 1zio | AP5 | Adenylate kinase | / | 0.440 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.440 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
| 2cl6 | CAG | GTPase HRas | / | 0.440 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.440 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.440 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.440 | |
| 2xvu | 9DN | Serum albumin | / | 0.440 | |
| 2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.440 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.440 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.440 | |
| 3pvw | QRX | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.440 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.440 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.440 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3t7v | SAM | 3-methylornithine synthase | / | 0.440 | |
| 3v4a | PK1 | Androgen receptor | / | 0.440 | |
| 3wyf | GTP | GTP-binding nuclear protein | / | 0.440 | |
| 3zxs | DLZ | Deoxyribodipyrimidine photolyase-related protein | / | 0.440 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.440 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.440 | |
| 4ceq | QCH | Integrase | / | 0.440 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.440 | |
| 4h0y | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4mkg | AP5 | Adenylate kinase | / | 0.440 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 4ram | PNM | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 4tl8 | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 4tlz | NAP | KtzI | / | 0.440 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.440 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 | |
| 5a3c | NAD | SIR2 family protein | / | 0.440 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5dbv | COA | Aldehyde Dehydrogenase | / | 0.440 | |
| 5eg3 | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.440 |