sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3fql	79Z	Genome polyprotein	2.7.7.48

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3fql	79Z	Genome polyprotein	2.7.7.48	1.000
1xe5	5FE	Plasmepsin-2	3.4.23.39	0.459
3oee	ANP	ATP synthase subunit alpha, mitochondrial	/	0.452
3oee	ANP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.452
2qbu	SAH	Precorrin-2 methyltransferase	/	0.448
1i7g	AZ2	Peroxisome proliferator-activated receptor alpha	/	0.447
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.443
2vke	TAC	Tetracycline repressor protein class D	/	0.443
1bil	0IU	Renin	3.4.23.15	0.442
3d91	REM	Renin	3.4.23.15	0.442