Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fmh | 533 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.826 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.818 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.739 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.718 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.705 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.698 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.686 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.649 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.630 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.622 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.619 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.612 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.604 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.590 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.582 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.576 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.576 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.572 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.569 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.568 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.567 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.565 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.565 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.562 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.552 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.549 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.548 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.545 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.541 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.539 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.537 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.529 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.527 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.521 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.521 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.519 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.519 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.514 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.511 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.510 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.510 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.509 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.498 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.498 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.491 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.489 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.487 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.483 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.482 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.482 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.480 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.478 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.478 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.478 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.477 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.475 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.475 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.475 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.473 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.472 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3cvu | FAD | RE11660p | / | 0.471 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.471 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.471 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.470 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.469 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.467 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.467 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.467 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.467 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.467 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.466 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.465 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.465 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.465 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.464 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.464 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.463 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.463 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.462 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.462 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.461 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.461 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.461 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.460 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.460 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.459 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.459 | |
| 3ieu | GDP | GTPase Era | / | 0.459 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.459 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.459 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.458 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.458 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.458 | |
| 3zuy | TCH | Transporter | / | 0.458 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 5a3b | APR | SIR2 family protein | / | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.457 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.457 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.457 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.457 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.457 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.456 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.456 | |
| 3fc1 | 52P | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.456 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.456 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.456 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.455 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.455 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.455 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.455 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 1c6z | ROC | Protease | / | 0.454 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.454 | |
| 1qvn | FRI | Interleukin-2 | / | 0.454 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.454 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.454 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.454 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.453 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.453 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.453 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.453 | |
| 3gi5 | K62 | Gag-Pol polyprotein | / | 0.453 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.453 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.453 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.452 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.451 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.451 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.451 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.450 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.450 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.450 | |
| 2fto | TMP | Thymidylate synthase | / | 0.450 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.450 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.450 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.449 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.449 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.449 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.449 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.449 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.448 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.448 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.448 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3gc7 | B45 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.447 | |
| 2ves | GVR | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.447 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.447 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.447 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4iva | 1J5 | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.447 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.446 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.446 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.446 | |
| 4hxy | NDP | Plm1 | / | 0.446 | |
| 4nfn | 2KC | Tau-tubulin kinase 1 | 2.7.11.1 | 0.446 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.446 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.445 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.445 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.445 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.445 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.445 | |
| 4r9u | ANP | Vitamin B12 import ATP-binding protein BtuD | / | 0.445 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.445 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.445 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.444 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.444 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.444 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.444 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.444 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.443 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1wbk | 568 | Pol protein | / | 0.443 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.443 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.443 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.443 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.443 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3zrk | ZRK | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.443 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.443 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 5upj | UIN | Gag-Pol polyprotein | / | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2ghm | LIC | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.442 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3lu8 | IQX | Serum albumin | / | 0.442 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.442 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 5a3c | NAD | SIR2 family protein | / | 0.442 | |
| 1dw6 | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.441 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.441 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.441 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.441 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.441 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.441 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.441 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.441 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.441 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 4q1w | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.441 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.440 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1osv | CHC | Bile acid receptor | / | 0.440 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.440 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.440 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3m6g | LO3 | Actin, alpha skeletal muscle | / | 0.440 | |
| 3s56 | ROC | Protease | / | 0.440 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.440 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4mgk | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.440 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.440 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.440 |