sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3flz | FLZ | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.811 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.794 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.757 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.733 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.730 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.700 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.686 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.640 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.615 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.609 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.606 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.596 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.596 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.592 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.590 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.582 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.580 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.577 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.573 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.567 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.564 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.562 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.559 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.558 | |
| 3fml | FML | Mitogen-activated protein kinase 14 | / | 0.556 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.553 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.553 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.552 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.549 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.538 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.534 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.533 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.533 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.529 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.529 | |
| 1bl6 | SB6 | Mitogen-activated protein kinase 14 | / | 0.528 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.525 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.522 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.521 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.518 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.517 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.514 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.514 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.513 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.512 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.510 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.510 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.509 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.508 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.507 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.507 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.505 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.505 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.505 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.500 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.498 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.498 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.497 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.496 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.495 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.490 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3fmj | FMJ | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.486 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.485 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.484 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.484 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.482 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 3zuy | TCH | Transporter | / | 0.482 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.481 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.478 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.478 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.478 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.478 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.477 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.476 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.475 | |
| 4l9q | 9TP | Serum albumin | / | 0.475 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.474 | |
| 2wq6 | FAD | RE11660p | / | 0.474 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.474 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.474 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.473 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.473 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.473 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.473 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.473 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.472 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.472 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.472 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.472 | |
| 5a3b | APR | SIR2 family protein | / | 0.472 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.471 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 2zaz | GK1 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.470 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.470 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.470 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.470 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.469 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.469 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.469 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.469 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.469 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.468 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1m7q | DQO | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.468 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.468 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.467 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.467 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.467 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.467 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.466 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.466 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.466 | |
| 1hii | C20 | Gag-Pol polyprotein | / | 0.466 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.466 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.466 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.466 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.466 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.466 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.466 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.466 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.466 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.465 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.465 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 4l8u | 9AZ | Serum albumin | / | 0.465 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.464 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.464 | |
| 3lfa | 1N1 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.464 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.464 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 3dck | KVI | Protease | / | 0.463 | |
| 3gi5 | K62 | Gag-Pol polyprotein | / | 0.463 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.462 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.462 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.462 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2p3c | 3TL | Protease | / | 0.462 | |
| 3cvu | FAD | RE11660p | / | 0.462 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.462 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.462 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.462 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.461 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.461 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3fc1 | 52P | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.461 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.460 | |
| 3cvy | FAD | RE11660p | / | 0.460 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.460 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.460 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.460 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.460 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.460 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.459 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.459 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.459 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3u9e | COA | Lmo1369 protein | / | 0.459 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.459 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.459 | |
| 4kbc | 1QJ | Casein kinase I isoform delta | 2.7.11.1 | 0.459 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.458 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.458 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.458 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.458 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.458 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.458 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.458 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.457 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.457 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 3dcr | KVS | Protease | / | 0.457 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.457 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.457 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.457 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.457 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.456 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.456 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.456 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.456 | |
| 3gob | HXX | DdmC | / | 0.456 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.456 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3oc1 | BMU | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.456 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.456 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 2a4f | AAU | V-1 protease | / | 0.455 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.455 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.455 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3s56 | ROC | Protease | / | 0.455 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 5a3c | NAD | SIR2 family protein | / | 0.455 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.455 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.454 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.453 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.453 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.453 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.453 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.453 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.453 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.453 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.453 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.453 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.452 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.452 | |
| 1n49 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 2y4g | TIR | TamL | / | 0.452 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.452 | |
| 3gc7 | B45 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.452 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.452 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.452 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.452 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.452 | |
| 5aac | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.452 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.452 | |
| 1hzz | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.451 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.451 | |
| 1qvn | FRI | Interleukin-2 | / | 0.451 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.451 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.451 | |
| 3sa0 | NRA | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.451 | |
| 4eh5 | 0OM | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.450 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.450 | |
| 1hvl | A76 | Gag-Pol polyprotein | / | 0.450 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.450 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 2wpw | ACO | Orf14 | / | 0.450 | |
| 2y3s | TIR | TamL | / | 0.450 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.450 | |
| 3i2l | 2NC | Protease | / | 0.450 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.450 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.450 | |
| 1f12 | 3HC | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.449 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.449 | |
| 2h12 | CMX | Citrate synthase | / | 0.449 | |
| 2nnp | ROC | Protease | / | 0.449 | |
| 2of4 | 979 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3iw6 | PP0 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3ndt | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3nyg | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.449 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.449 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1osv | CHC | Bile acid receptor | / | 0.448 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.448 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.448 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.448 | |
| 3k4v | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 2nmy | ROC | Protease | / | 0.447 | |
| 2oo5 | TXD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.447 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.447 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.447 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.447 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.447 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.447 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.447 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.446 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.446 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.446 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.446 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.446 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.446 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3stx | BKA | Methylketone synthase I | / | 0.446 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.446 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.446 | |
| 3vfb | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.446 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 1bl7 | SB4 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.445 | |
| 1fml | RTL | Retinol dehydratase | / | 0.445 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.445 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.445 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.445 | |
| 2idw | 017 | Protease | / | 0.445 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.445 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.445 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.445 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.445 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3d1x | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.445 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.445 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
| 4hxy | NDP | Plm1 | / | 0.445 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.445 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1qy5 | NEC | Endoplasmin | / | 0.444 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.444 | |
| 2bpv | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.444 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.444 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.444 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 3wec | AUI | Cytochrome P450 | / | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4eym | 0RX | Mitogen-activated protein kinase 13 | 2.7.11.24 | 0.444 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.444 | |
| 4nvk | 2NY | Peroxidase | / | 0.444 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.444 | |
| 4yqf | GDP | Septin-9 | / | 0.444 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 1ec2 | BEJ | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.443 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.443 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.443 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2y3r | TRK | TamL | / | 0.443 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.443 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.443 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.443 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.443 | |
| 3rus | ADP | Chaperonin | / | 0.443 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.443 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.443 | |
| 4e2b | FMN | Dehydrogenase | / | 0.443 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.443 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.443 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.442 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tys | DHF | Thymidylate synthase | / | 0.442 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2a1e | IPF | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2o4p | TPV | Protease | / | 0.442 | |
| 2obj | VRV | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2qhc | AB1 | Protease | / | 0.442 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.442 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3jvw | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.442 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4djr | 0KJ | Pol polyprotein | / | 0.442 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4gb2 | 0LQ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4pd6 | URI | Nucleoside permease | / | 0.442 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1ffi | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.441 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.441 | |
| 2ad5 | ADP | CTP synthase | / | 0.441 | |
| 2cvw | GDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.441 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2f3k | RO1 | Protease | / | 0.441 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.441 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.441 | |
| 2y3r | TIR | TamL | / | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.441 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.441 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.441 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.441 | |
| 4n6b | COA | Uncharacterized protein | / | 0.441 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.441 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.440 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.440 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.440 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.440 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.440 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3a3g | DLZ | Lumazine protein | / | 0.440 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 3d1y | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.440 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.440 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.440 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3vf5 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4dlj | 6RG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.440 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.440 | |
| 4s34 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.440 |