sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3fl4	FL4	Mitogen-activated protein kinase 14

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3fl4	FL4	Mitogen-activated protein kinase 14	/	1.000
3fkn	FKN	Mitogen-activated protein kinase 14	/	0.737
3fko	FKO	Mitogen-activated protein kinase 14	/	0.707
2gfs	PQB	Mitogen-activated protein kinase 14	/	0.559
3ds6	A17	Mitogen-activated protein kinase 14	/	0.536
3flw	FLW	Mitogen-activated protein kinase 14	/	0.521
3hub	469	Mitogen-activated protein kinase 14	/	0.508
3zsh	469	Mitogen-activated protein kinase 14	/	0.507
3itz	P66	Mitogen-activated protein kinase 14	/	0.479
3fmm	XI2	Mitogen-activated protein kinase 14	/	0.475
3c5u	P41	Mitogen-activated protein kinase 14	/	0.474
1ove	358	Mitogen-activated protein kinase 14	/	0.456
3uvq	FS8	Mitogen-activated protein kinase 14	/	0.447
1zzl	TZY	Mitogen-activated protein kinase 14	/	0.443
3fsk	RO6	Mitogen-activated protein kinase 14	/	0.441