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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3fkoFKOMitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3fkoFKOMitogen-activated protein kinase 14/1.000
3fl4FL4Mitogen-activated protein kinase 14/0.780
3fknFKNMitogen-activated protein kinase 14/0.714
2gfsPQBMitogen-activated protein kinase 14/0.583
3fmmXI2Mitogen-activated protein kinase 14/0.571
3zsh469Mitogen-activated protein kinase 14/0.550
3hub469Mitogen-activated protein kinase 14/0.539
3itzP66Mitogen-activated protein kinase 14/0.533
3ds6A17Mitogen-activated protein kinase 14/0.525
1ove358Mitogen-activated protein kinase 14/0.499
1zzlTZYMitogen-activated protein kinase 14/0.495
1w7h3IPMitogen-activated protein kinase 14/0.483
3flwFLWMitogen-activated protein kinase 14/0.476
3gc9B45Mitogen-activated protein kinase 112.7.11.240.467
2zb1GK4Mitogen-activated protein kinase 14/0.458
3c5uP41Mitogen-activated protein kinase 14/0.456
3flyFLYMitogen-activated protein kinase 14/0.454
1wbwLI4Mitogen-activated protein kinase 14/0.451
3fln3FNMitogen-activated protein kinase 14/0.447
3uvqFS8Mitogen-activated protein kinase 14/0.446
3fi4FI4Mitogen-activated protein kinase 14/0.445
3hp552PMitogen-activated protein kinase 14/0.443
3rinI2OMitogen-activated protein kinase 14/0.443