sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3fe1	ADP	Heat shock 70 kDa protein 6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3fe1	ADP	Heat shock 70 kDa protein 6	/	1.000
1ats	ADP	Heat shock cognate 71 kDa protein	/	0.484
1atr	ADP	Heat shock cognate 71 kDa protein	/	0.473
5f2r	ACP	78 kDa glucose-regulated protein	/	0.462
1ngb	ADP	Heat shock cognate 71 kDa protein	/	0.456
2qwq	ADP	Heat shock cognate 71 kDa protein	/	0.454
1ngc	ADP	Heat shock cognate 71 kDa protein	/	0.453
2qwn	ADP	Heat shock cognate 71 kDa protein	/	0.449
3ldl	ATP	78 kDa glucose-regulated protein	/	0.442
1ngh	ATP	Heat shock cognate 71 kDa protein	/	0.441