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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.581.000
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.643
1s63778Protein farnesyltransferase subunit beta2.5.1.580.642
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.625
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.625
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.615
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.615
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.614
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.613
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.606
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.605
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.596
4gtm7TMProtein farnesyltransferase subunit beta2.5.1.580.596
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.587
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.582
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.570
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.568
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.568
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.567
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.563
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.518
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.518
1n4qLYS_CYS_VAL_ILE_LEUGeranylgeranyl transferase type-1 subunit beta2.5.1.590.513
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.512
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.501
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.484
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.484
3q7fED2Uncharacterized protein/0.478
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.473
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.462
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.458