sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3eq7 | X99 | Prolyl endopeptidase | 3.4.21.26 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3eq7 | X99 | Prolyl endopeptidase | 3.4.21.26 | 1.000 | |
| 4bcd | TDV | Prolyl endopeptidase | 3.4.21.26 | 0.688 | |
| 1e8m | P0H | Prolyl endopeptidase | 3.4.21.26 | 0.657 | |
| 1uop | GLY_PHE_GLU_PRO | Prolyl endopeptidase | 3.4.21.26 | 0.574 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.501 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.497 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.496 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.491 | |
| 5cb4 | ACP | Tubulin tyrosine ligase | / | 0.491 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.488 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.487 | |
| 4l4x | NDP | AmphI | / | 0.486 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.484 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.484 | |
| 4mob | COA | Acyl-coenzyme A thioesterase 12 | 3.1.2.1 | 0.484 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.483 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.482 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.481 | |
| 3qfc | NAP | NADPH--cytochrome P450 reductase | / | 0.481 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.480 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.479 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.479 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.479 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.479 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.478 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.477 | |
| 3cvu | FAD | RE11660p | / | 0.477 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.477 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.476 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.476 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.476 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.475 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.475 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.473 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.473 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.473 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.471 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.471 | |
| 2zxu | DST | tRNA dimethylallyltransferase | 2.5.1.75 | 0.471 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 3i6o | GR6 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.471 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.471 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.471 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.470 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.470 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.470 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2cej | 1AH | Pol protein | / | 0.469 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.469 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.468 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.468 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.467 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.467 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.467 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.467 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.467 | |
| 5dby | NPS | Serum albumin | / | 0.467 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.466 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.466 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.466 | |
| 4u7w | NDP | MxaA | / | 0.466 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.466 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.465 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.465 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.465 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.464 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.464 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.464 | |
| 3cvy | FAD | RE11660p | / | 0.464 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.464 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.464 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.464 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.463 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.463 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.463 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.463 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.463 | |
| 3m2r | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.463 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.463 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.462 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.462 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.462 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2p3d | 3TL | Protease | / | 0.461 | |
| 2q54 | MU1 | Protease | / | 0.461 | |
| 3i2l | 2NC | Protease | / | 0.461 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.461 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.460 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.460 | |
| 2icx | UTP | UTP--glucose-1-phosphate uridylyltransferase 2 | 2.7.7.9 | 0.460 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.460 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.460 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.460 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.460 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.460 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.459 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4nvk | 2NY | Peroxidase | / | 0.459 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.459 | |
| 4xr9 | TMP | CalS8 | / | 0.459 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.459 | |
| 1c6x | 3IN | Protease | / | 0.458 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3w10 | RO9 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.458 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.458 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.458 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.458 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 1o6k | ANP | RAC-beta serine/threonine-protein kinase | 2.7.11.1 | 0.457 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.457 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.457 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.457 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 1b6l | PI4 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.456 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 2bun | FAD | AppA protein | / | 0.456 | |
| 2fdd | 385 | Pol protein | / | 0.456 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.456 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 3b9l | AZZ | Serum albumin | / | 0.456 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.456 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.456 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.456 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.456 | |
| 4ra3 | TFX | Beta-2-microglobulin | / | 0.456 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.455 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.455 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.455 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 3aje | ANP | Threonylcarbamoyl-AMP synthase | 2.7.7.87 | 0.455 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.455 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.455 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.455 | |
| 3qfr | NAP | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.455 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.455 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.455 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.455 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.454 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.454 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.454 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
| 2b60 | RIT | Pol polyprotein | / | 0.454 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.454 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.454 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.454 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3gwl | FAD | FAD-linked sulfhydryl oxidase | 1.8.3.2 | 0.454 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.454 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.454 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.454 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.454 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.454 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.454 | |
| 5ani | ES4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.454 | |
| 5ca0 | ACP | Tubulin tyrosine ligase | / | 0.454 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2cen | 4AH | Protease | / | 0.453 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.453 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.453 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.453 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.453 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 1axw | MTX | Thymidylate synthase | / | 0.452 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.452 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.452 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.452 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.452 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.452 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.452 | |
| 2hf8 | GSP | Probable hydrogenase nickel incorporation protein HypB | / | 0.452 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.452 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.452 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.452 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.452 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.451 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.451 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.451 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.451 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.451 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.451 | |
| 4eh5 | IRG | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4jxr | ACO | Acetyltransferase | / | 0.451 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.451 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.450 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.450 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.450 | |
| 1sc6 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 1y8q | ATP | SUMO-activating enzyme subunit 2 | 6.3.2 | 0.450 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.450 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2p3a | 3TL | Pol protein | / | 0.450 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.450 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.449 | |
| 1h0v | UN4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1jbp | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1qvn | FRI | Interleukin-2 | / | 0.449 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.449 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.449 | |
| 2oji | 33A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.449 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.449 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.449 | |
| 1b39 | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.448 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.448 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.448 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.448 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.448 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.448 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.448 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.448 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.448 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.448 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 4hzp | COA | Conserved hypthetical protein | / | 0.448 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.448 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.448 | |
| 6adh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.447 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.447 | |
| 1k6m | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | 2.7.1.105 | 0.447 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1p4a | PCP | Pur operon repressor | / | 0.447 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.447 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.447 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.447 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.447 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.447 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.447 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4ks7 | X4Z | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.447 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.446 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.446 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.446 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.446 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.446 | |
| 1y7t | NDP | Malate dehydrogenase | / | 0.446 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.446 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.446 | |
| 3ag9 | A02 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.446 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.446 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.446 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4dru | 0LN | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.446 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4qf7 | C0R | Phospholipase A2 VRV-PL-VIIIa | / | 0.446 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.446 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.445 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.445 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.445 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.445 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 2ojj | 82A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 2xye | CXG | Gag-Pol polyprotein | / | 0.445 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.445 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.445 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.445 | |
| 3n4m | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 3ndu | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3rnn | RNN | Glutamate receptor 2 | / | 0.445 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.445 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4c2u | ANP | DNA helicase | / | 0.445 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.445 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4qgd | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 4zrn | UPG | UDP-glucose 4-epimerase, putative | / | 0.445 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.445 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.444 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.444 | |
| 1mqb | ANP | Ephrin type-A receptor 2 | 2.7.10.1 | 0.444 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.444 | |
| 1yt0 | ADP | Endoplasmin | / | 0.444 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.444 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.444 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 2xzw | ATP | Nitrogen regulatory protein P-II | / | 0.444 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.444 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.444 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.444 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.444 | |
| 4i8q | NAD | Putative betaine aldehyde dehyrogenase | / | 0.444 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.444 | |
| 4k3n | 1OT | M17 leucyl aminopeptidase | / | 0.444 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.444 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.443 | |
| 1hih | C20 | Gag-Pol polyprotein | / | 0.443 | |
| 1ht2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.443 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.443 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.443 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.443 | |
| 2hah | 3TL | POL protein | / | 0.443 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.443 | |
| 2ozo | ANP | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.443 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.443 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2xdr | NDP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.443 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.443 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.443 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.443 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.443 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.443 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4cj4 | S3G | Integrase | / | 0.443 | |
| 4cjp | 4D2 | Integrase | / | 0.443 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.443 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.442 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.442 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 2yxl | SFG | 450aa long hypothetical fmu protein | / | 0.442 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.442 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3ncr | ADP | Nitrogen regulatory protein P-II (GlnB-2) | / | 0.442 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.442 | |
| 4cf1 | IY7 | Integrase | / | 0.442 | |
| 4cfc | 7NV | Integrase | / | 0.442 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.442 | |
| 4pjj | ADP | Unconventional myosin-VI | / | 0.442 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.442 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.442 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.442 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.442 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.441 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.441 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1mui | AB1 | Protease | / | 0.441 | |
| 1sdv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.441 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.441 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2izt | 23D | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 2p2x | SAH | Diphthine synthase | / | 0.441 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.441 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.441 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.441 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.441 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.441 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.441 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3dkv | AP5 | Adenylate kinase | / | 0.441 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3od0 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.441 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.441 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.441 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 4ibm | IR1 | Insulin receptor | 2.7.10.1 | 0.441 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4lb2 | DM5 | Serum albumin | / | 0.441 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
| 4s32 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4yfy | 1YJ | VioF | / | 0.441 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.441 | |
| 1c6y | MK1 | Protease | / | 0.440 | |
| 1gle | ADP | Glycerol kinase | / | 0.440 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.440 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.440 | |
| 1v8k | ANP | Kinesin-like protein KIF2C | / | 0.440 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1xjn | DTP | Vitamin B12-dependent ribonucleotide reductase | / | 0.440 | |
| 2rkf | AB1 | Pol protein | / | 0.440 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2z7l | S91 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.440 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.440 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4b1v | ATP | Actin, alpha skeletal muscle | / | 0.440 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.440 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4hjf | C2E | GGDEF family protein | / | 0.440 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4pk4 | ADP | Unconventional myosin-VI | / | 0.440 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 5im3 | DTP | Ribonucleoside-diphosphate reductase | / | 0.440 |