Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3ekp478Gag-Pol polyprotein3.4.23.16

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3ekp478Gag-Pol polyprotein3.4.23.161.000
4hdfG52Gag-Pol polyprotein3.4.23.160.588
3em4DR7Gag-Pol polyprotein3.4.23.160.566
3kdcJZPGag-Pol polyprotein3.4.23.160.564
2aoe0Q4Gag-Pol polyprotein3.4.23.160.563
3zpsEQMGag-Pol polyprotein3.4.23.160.562
1ivp1ZKGag-Pol polyprotein/0.558
1rl8RITGag-Pol polyprotein3.4.23.160.557
2pk6O33V-1 protease/0.554
3a2oKNJGag-Pol polyprotein3.4.23.160.554
3ekt017Gag-Pol polyprotein3.4.23.160.554
3linE13Protease/0.554
2fdd385Pol protein/0.553
3hzc2NCProtease/0.552
4njvRITProtease/0.552
3cyw017Gag-Pol polyprotein3.4.23.160.551
4djoMK5Pol polyprotein/0.550
3dk1G05Gag-Pol polyprotein3.4.23.160.549
3ggaGGWGag-Pol polyprotein/0.548
2pk5075Protease/0.545
4kb9G79Protease/0.545
3ekqROCGag-Pol polyprotein3.4.23.160.543
1hvsA77Gag-Pol polyprotein/0.542
2bqvA1AProtease/0.542
1hxbROCGag-Pol polyprotein3.4.23.160.541
2fxeDR7Gag-Pol polyprotein3.4.23.160.541
2qi3MZ5Gag-Pol polyprotein/0.541
3qn8NI7Gag-Pol polyprotein3.4.23.160.541
2f81017Gag-Pol polyprotein3.4.23.160.539
2xyfG40Gag-Pol polyprotein/0.539
1ec2BEJGag-Pol polyprotein3.4.23.160.537
1w5yBE6Gag-Pol polyprotein3.4.23.160.537
2p3b3TLV-1 PROTEASE protein/0.537
2p3b3TLV-1 protease/0.537
4hdbG52Gag-Pol polyprotein3.4.23.160.537
2idw017Protease/0.536
2ieo017Protease/0.536
1difA85Gag-Pol polyprotein/0.535
3vfa031Gag-Pol polyprotein3.4.23.160.534
4a4qUX9Pol protein/0.534
2qd6065Gag-Pol polyprotein3.4.23.160.533
3ok9G52Gag-Pol polyprotein3.4.23.160.533
2a1eIPFGag-Pol polyprotein3.4.23.160.532
2nnkROCProtease/0.532
2cem2AHPol protein/0.531
4ye3G04Gag-Pol polyprotein3.4.23.160.531
2aquDR7Gag-Pol polyprotein3.4.23.160.530
3gi6D78Gag-Pol polyprotein/0.530
3ndxRITGag-Pol polyprotein3.4.23.160.530
4a6cQG9Gag-Pol polyprotein3.4.23.160.530
1ffi2NCGag-Pol polyprotein3.4.23.160.529
1fgc2NCGag-Pol polyprotein3.4.23.160.529
1hiv1ZKGag-Pol polyprotein/0.529
3vf5031Gag-Pol polyprotein3.4.23.160.529
3sa755AProtease/0.527
2uy0HV1Gag-Pol polyprotein3.4.23.160.526
3bva2NCGag-Pol polyprotein3.4.23.160.526
3k4vROCGag-Pol polyprotein3.4.23.160.526
3ndwRITGag-Pol polyprotein3.4.23.160.526
2nmyROCProtease/0.525
3ekwDR7Gag-Pol polyprotein3.4.23.160.525
3t3c017Gag-Pol polyprotein3.4.23.160.525
2i4uDJRProtease/0.524
3tl9ROCGag-Pol polyprotein3.4.23.160.524
1t7kBH0Gag-Pol polyprotein3.4.23.160.523
2qd8065Gag-Pol polyprotein3.4.23.160.523
4rvj478Protease/0.523
1ec3MS3Gag-Pol polyprotein3.4.23.160.522
3zptM8YGag-Pol polyprotein3.4.23.160.522
4hdpG52Gag-Pol polyprotein3.4.23.160.522
1hvjA78Gag-Pol polyprotein/0.521
3bgcLJHGag-Pol polyprotein3.4.23.160.521
3s85LK0Gag-Pol polyprotein/0.521
3kfr3TLGag-Pol polyprotein/0.520
3nyg2NCGag-Pol polyprotein3.4.23.160.519
3sa4F72Protease/0.519
3ggxGGXGag-Pol polyprotein/0.518
4djr0KJPol polyprotein/0.518
3kf03TLGag-Pol polyprotein/0.517
3nxe2NCProtease/0.517
4djpM73Pol polyprotein/0.517
1t7i017Gag-Pol polyprotein3.4.23.160.516
2i4xKGQProtease/0.516
1a9mU0EGag-Pol polyprotein/0.514
2f3kRO1Protease/0.514
3em6017Gag-Pol polyprotein3.4.23.160.514
3jw2017Gag-Pol polyprotein3.4.23.160.514
4djqM86Pol polyprotein/0.514
4j55031Gag-Pol polyprotein3.4.23.160.513
2qnnQN1Gag-Pol polyprotein3.4.23.160.512
3sa6F71Protease/0.512
2fde385Gag-Pol polyprotein3.4.23.160.511
2qd7065Gag-Pol polyprotein3.4.23.160.511
2rkfAB1Pol protein/0.511
1ff02NCGag-Pol polyprotein3.4.23.160.510
3el9DR7Gag-Pol polyprotein3.4.23.160.510
3pwrROCGag-Pol polyprotein3.4.23.160.510
3ttp017Gag-Pol polyprotein3.4.23.160.510
1xl5190Gag-Pol polyprotein3.4.23.160.509
3bgbLJGGag-Pol polyprotein3.4.23.160.509
1fg62NCGag-Pol polyprotein3.4.23.160.508
2uxzHI1Gag-Pol polyprotein3.4.23.160.508
3d1yROCGag-Pol polyprotein3.4.23.160.508
3oxxDR7Gag-Pol polyprotein3.4.23.160.508
3sabF78Protease/0.508
1msmJE2Gag-Pol polyprotein3.4.23.160.507
3oxcROCProtease/0.507
4a6bQG8Gag-Pol polyprotein3.4.23.160.507
1wbmBLLPol protein/0.506
2q5kAB1Protease/0.506
3ndtROCGag-Pol polyprotein3.4.23.160.506
3zpuM8BGag-Pol polyprotein3.4.23.160.506
1d4iBEGGag-Pol polyprotein3.4.23.160.505
1hvkA79Gag-Pol polyprotein/0.505
1vijBAYGag-Pol polyprotein/0.505
2cen4AHProtease/0.505
2i4wKGQProtease/0.505
3sacAF8Protease/0.505
1n49RITGag-Pol polyprotein3.4.23.160.504
1w5xBE5Gag-Pol polyprotein3.4.23.160.504
1yt9OISGag-Pol polyprotein/0.504
2bb9AKCGag-Pol polyprotein3.4.23.160.504
1ohr1UNV-1 PROTEASE protein/0.503
2xyeCXGGag-Pol polyprotein/0.503
3kfn3TLGag-Pol polyprotein/0.503
3s56ROCProtease/0.503
4qgiROCGag-Pol polyprotein3.4.23.160.503
1d4yTPVGag-Pol polyprotein3.4.23.160.502
2hc0AB2Protease/0.501
2pyn1UNGag-Pol polyprotein3.4.23.160.501
3ekyDR7Gag-Pol polyprotein3.4.23.160.501
3fx5KNIGag-Pol polyprotein3.4.23.160.501
3nduROCGag-Pol polyprotein3.4.23.160.501
3sa5A69Protease/0.501
1hpoUNIGag-Pol polyprotein3.4.23.160.500
1zsr0ZTGag-Pol polyprotein3.4.23.160.500
2bpw1INGag-Pol polyprotein3.4.23.160.500
2qi6MZ8Gag-Pol polyprotein/0.500
1hpxKNIGag-Pol polyprotein/0.499
1k2b0Q4Gag-Pol polyprotein3.4.23.160.499
1sdvMK1Gag-Pol polyprotein3.4.23.160.499
2a4fAAUV-1 protease/0.499
2qhzMZ2Gag-Pol polyprotein/0.499
3liqE14Protease/0.499
3nwq2NCGag-Pol polyprotein3.4.23.160.499
3o9bK2APol polyprotein/0.498
1hvlA76Gag-Pol polyprotein/0.497
2f80017Gag-Pol polyprotein3.4.23.160.497
2ien017Gag-Pol polyprotein3.4.23.160.497
2wl05AHGag-Pol polyprotein/0.497
3mxeK54Gag-Pol polyprotein3.4.23.160.497
1vikBAYGag-Pol polyprotein/0.496
2bpy3INGag-Pol polyprotein3.4.23.160.496
2upjU02Gag-Pol polyprotein3.4.23.160.496
3nuo478Gag-Pol polyprotein3.4.23.160.496
1dw60Q4Gag-Pol polyprotein3.4.23.160.495
2b7zMK1Gag-Pol polyprotein/0.495
2wkz5AHGag-Pol polyprotein/0.495
3oxv478Gag-Pol polyprotein3.4.23.160.495
3sa323XProtease/0.495
1hosPHPGag-Pol polyprotein/0.494
3bvb017Gag-Pol polyprotein3.4.23.160.494
1d4sTPVGag-Pol polyprotein3.4.23.160.493
2qi7MZ9Gag-Pol polyprotein/0.493
4dfg0JVGag-Pol polyprotein3.4.23.160.493
1wbk568Pol protein/0.492
3bxsDRSGag-Pol polyprotein3.4.23.160.492
3s43478Protease/0.492
3t113T1Gag-Pol polyprotein3.4.23.160.492
1hxwRITGag-Pol polyprotein/0.491
3el1DR7Gag-Pol polyprotein3.4.23.160.491
3gi4K60Gag-Pol polyprotein/0.491
3o9cK20Pol polyprotein/0.491
4dqe017Gag-Pol polyprotein/0.491
1ec1BEEGag-Pol polyprotein3.4.23.160.490
2avvMK1Gag-Pol polyprotein3.4.23.160.490
3vfb031Gag-Pol polyprotein3.4.23.160.490
4njsG08Protease/0.490
4q1y017Gag-Pol polyprotein3.4.23.160.490
1npa3NHGag-Pol polyprotein3.4.23.160.489
1npwLGZGag-Pol polyprotein3.4.23.160.489
1odw0E8Gag-Pol polyprotein3.4.23.160.489
2bpz3INGag-Pol polyprotein3.4.23.160.489
3i2l2NCProtease/0.489
4njt017Protease/0.489
1hviA77Protease/0.488
2qci065Gag-Pol polyprotein3.4.23.160.488
3qp0NI8Gag-Pol polyprotein3.4.23.160.488
3sa9A68Protease/0.488
3uhl2NCGag-Pol polyprotein3.4.23.160.488
1bwaXV6Gag-Pol polyprotein3.4.23.160.487
2bpv1INGag-Pol polyprotein3.4.23.160.487
2i4vDJRV-1 protease/0.487
3el4ROCGag-Pol polyprotein3.4.23.160.487
3i6oGR6Gag-Pol polyprotein3.4.23.160.487
1ebwBEIGag-Pol polyprotein3.4.23.160.486
1hsgMK1Gag-Pol polyprotein/0.486
3cyxROCGag-Pol polyprotein3.4.23.160.486
3st5G89Gag-Pol polyprotein3.4.23.160.486
2qnpQN2Gag-Pol polyprotein3.4.23.160.485
3djkG55Gag-Pol polyprotein3.4.23.160.485
3jvwDMPGag-Pol polyprotein3.4.23.160.485
3kddJZQGag-Pol polyprotein3.4.23.160.485
3litE15Protease/0.485
3nu4478Gag-Pol polyprotein3.4.23.160.485
4hegG52Gag-Pol polyprotein3.4.23.160.485
7upjINUGag-Pol polyprotein3.4.23.160.485
2avm2NCGag-Pol polyprotein3.4.23.160.484
3vf7031Gag-Pol polyprotein3.4.23.160.484
1bv7XV6Gag-Pol polyprotein3.4.23.160.483
1iiq0ZRGag-Pol polyprotein3.4.23.160.483
2f8g017Gag-Pol polyprotein3.4.23.160.483
3dcrKVSProtease/0.483
4j5j478Gag-Pol polyprotein3.4.23.160.483
1ec0BEDGag-Pol polyprotein3.4.23.160.482
2qnqQN3Gag-Pol polyprotein3.4.23.160.482
3nu9478Gag-Pol polyprotein3.4.23.160.482
3qrsNK8Gag-Pol polyprotein3.4.23.160.482
1sh9RITGag-Pol polyprotein3.4.23.160.481
2hb3GRLProtease/0.481
4njuTPVProtease/0.481
2q3kMUWGag-Pol polyprotein/0.480
1a8k0Q4Gag-Pol polyprotein3.4.23.160.479
1sguMK1Gag-Pol polyprotein3.4.23.160.479
1w5vBE3Gag-Pol polyprotein3.4.23.160.479
2p3d3TLProtease/0.479
3qbfJHGGag-Pol polyprotein3.4.23.160.479
1b6lPI4Gag-Pol polyprotein3.4.23.160.478
1c6yMK1Protease/0.478
1tcxIM1Gag-Pol polyprotein3.4.23.160.478
1zsf0ZSGag-Pol polyprotein3.4.23.160.478
2o4pTPVProtease/0.478
3cktYDPGag-Pol polyprotein3.4.23.160.478
3dckKVIProtease/0.478
3livE16Protease/0.478
3nls016Gag-Pol polyprotein3.4.23.160.478
3i7eDJRGag-Pol polyprotein/0.477
3o9eA60Pol polyprotein/0.477
3tog079Gag-Pol polyprotein2.7.7.490.477
1bdlIM1Gag-Pol polyprotein3.4.23.160.476
2i4dQFIProtease/0.475
2q54MU1Protease/0.475
2qhcAB1Protease/0.475
2r43G3GGag-Pol polyprotein3.4.23.160.475
3d1z017Gag-Pol polyprotein3.4.23.160.475
3jvy017Gag-Pol polyprotein3.4.23.160.475
3saa77FProtease/0.475
3wsjMK1Protease/0.475
1d4kPI8Gag-Pol polyprotein3.4.23.160.474
1fg80Q4Gag-Pol polyprotein3.4.23.160.474
1sbgIM1Gag-Pol polyprotein/0.474
1t3r017Gag-Pol polyprotein3.4.23.160.474
4dqc017Gag-Pol polyprotein/0.474
1ajvNMBGag-Pol polyprotein3.4.23.160.473
1daz0Q4Gag-Pol polyprotein3.4.23.160.473
3d1xROCGag-Pol polyprotein3.4.23.160.473
3nu6478Gag-Pol polyprotein3.4.23.160.473
3o9fK2DGag-Pol polyprotein/0.473
1fej2NCGag-Pol polyprotein3.4.23.160.472
1ida0POGag-Pol polyprotein3.4.23.470.472
1k1u0Q4Gag-Pol polyprotein3.4.23.160.472
1npvL27Gag-Pol polyprotein3.4.23.160.472
2qi5MZ7Gag-Pol polyprotein/0.472
1c6zROCProtease/0.471
1d4hBEHGag-Pol polyprotein3.4.23.160.471
3ekv478Gag-Pol polyprotein3.4.23.160.471
3el51UNGag-Pol polyprotein/0.471
1k6vXN2Gag-Pol polyprotein3.4.23.160.470
3lzv017Gag-Pol polyprotein3.4.23.160.470
1idb0DOGag-Pol polyprotein/0.469
2i0dMUTProtease/0.469
2q631UNGag-Pol polyprotein3.4.23.160.469
3qaaG04Gag-Pol polyprotein3.4.23.160.469
3s54017Protease/0.469
1ebyBEBGag-Pol polyprotein3.4.23.160.468
1hihC20Gag-Pol polyprotein/0.468
1hshMK1Gag-Pol polyprotein/0.468
2pqzG0GGag-Pol polyprotein3.4.23.160.468
2r5pMK1Gag-Pol polyprotein/0.468
3bheBZNGag-Pol polyprotein3.4.23.160.468
3qrmNK7Gag-Pol polyprotein3.4.23.160.468
3sa8K83Protease/0.468
2qi0MZ3Gag-Pol polyprotein/0.467
1c6x3INProtease/0.466
1jld0PPGag-Pol polyprotein/0.466
1meuDMPGag-Pol polyprotein3.4.23.160.466
2nnpROCProtease/0.466
2p3a3TLPol protein/0.466
3em3478Gag-Pol polyprotein3.4.23.160.466
3ggu017Gag-Pol polyprotein3.4.23.160.466
3o9gF53Gag-Pol polyprotein/0.466
1bdrIM1Gag-Pol polyprotein3.4.23.160.465
3kfs3TLGag-Pol polyprotein/0.465
1d4jMSCGag-Pol polyprotein3.4.23.160.464
2cej1AHPol protein/0.464
1b6pPI7Gag-Pol polyprotein3.4.23.160.463
1d4lPI9Gag-Pol polyprotein3.4.23.160.463
2z54AB1Gag-Pol polyprotein3.4.23.160.463
3gi5K62Gag-Pol polyprotein/0.463
1b6kPI5Gag-Pol polyprotein3.4.23.160.462
1sduMK1Gag-Pol polyprotein3.4.23.160.462
1sivPSIGag-Pol polyprotein/0.462
2fleAIProtease/0.462
2fxdDR7Pol polyprotein/0.462
3el01UNGag-Pol polyprotein3.4.23.160.462
1ebzBECGag-Pol polyprotein3.4.23.160.461
1fff0Q4Gag-Pol polyprotein3.4.23.160.461
1z1rHBHGag-Pol polyprotein3.4.23.160.461
3nu5478Gag-Pol polyprotein3.4.23.160.461
1hiiC20Gag-Pol polyprotein/0.460
3oy4017Gag-Pol polyprotein3.4.23.160.460
4gb20LQGag-Pol polyprotein2.7.7.490.460
4hla017Gag-Pol polyprotein3.4.23.160.460
4k4p3TLGag-Pol polyprotein/0.460
9hvp0E9Gag-Pol polyprotein/0.460
1odyLP1Gag-Pol polyprotein3.4.23.160.459
2hs1017Protease/0.459
1bai0Q4Gag-Pro polyprotein/0.458
1g35AHFGag-Pol polyprotein3.4.23.160.458
1muiAB1Protease/0.458
1sdtMK1Gag-Pol polyprotein3.4.23.160.458
2qhyMZ1Gag-Pol polyprotein/0.458
3lzu017Gag-Pol polyprotein3.4.23.160.458
3ufnROCGag-Pol polyprotein/0.458
4dqh017Gag-Pol polyprotein/0.458
1kzkJE2Gag-Pol polyprotein3.4.23.160.457
1z1hHBBGag-Pol polyprotein3.4.23.160.457
2aidTHKGag-Pol polyprotein3.4.23.160.457
2pym1UNGag-Pol polyprotein3.4.23.160.457
3o99K13Pol polyprotein/0.457
3oxw017Gag-Pol polyprotein3.4.23.160.457
1iziQ50Gag-Pol polyprotein3.4.23.160.456
2b60RITPol polyprotein/0.456
1g2kNM1Gag-Pol polyprotein3.4.23.160.455
1izhQ50Protease/0.455
1mtrPI6Gag-Pol polyprotein3.4.23.160.455
2bbbHH1Gag-Pol polyprotein3.4.23.160.455
2q641UNGag-Pol polyprotein3.4.23.160.455
1a8g2Z4Gag-Pol polyprotein3.4.23.160.454
1qbsDMPGag-Pol polyprotein3.4.23.160.454
2qi1MZ4Gag-Pol polyprotein/0.454
4dqf017Gag-Pol polyprotein/0.454
1b6mPI6Gag-Pol polyprotein3.4.23.160.453
3o9iA61Gag-Pol polyprotein/0.453
3pwm017Gag-Pol polyprotein3.4.23.160.453
4i8zG08Gag-Pol polyprotein3.4.23.160.453
1bv9XV6Gag-Pol polyprotein3.4.23.160.452
2psuMUUProtease/0.452
2r38G4GGag-Pol polyprotein3.4.23.160.452
3qroNK9Gag-Pol polyprotein3.4.23.160.452
2pwcG3GGag-Pol polyprotein3.4.23.160.451
2qi4MZ6Gag-Pol polyprotein/0.451
2r3wG3GGag-Pol polyprotein3.4.23.160.451
3o9dK19Pol polyprotein/0.451
3o9hK2EGag-Pol polyprotein/0.451
2avsMK1Gag-Pol polyprotein3.4.23.160.450
4dqb017Gag-Pol polyprotein/0.450
1qbu846Gag-Pol polyprotein3.4.23.160.449
2qak1UNGag-Pol polyprotein3.4.23.160.449
3ecg065Gag-Pol polyprotein3.4.23.470.449
3mxdK53Gag-Pol polyprotein3.4.23.160.449
3qpjN4IGag-Pol polyprotein3.4.23.160.449
1bwb146Gag-Pol polyprotein3.4.23.160.448
3nwxKVSGag-Pol polyprotein3.4.23.160.448
1c70L75Protease/0.447
1mesDMPGag-Pol polyprotein3.4.23.160.447
1tcwIM1Gag-Pol polyprotein/0.447
3mws017Pol protein/0.447
3nuj478Gag-Pol polyprotein3.4.23.160.447
3o9aK14Pol polyprotein/0.447
3ucb017Gag-Pol polyprotein/0.447
4q1w017Gag-Pol polyprotein3.4.23.160.447
1hvrXK2Gag-Pol polyprotein/0.446
2hs2017Protease/0.446
2p3c3TLProtease/0.446
3qihNI7Gag-Pol polyprotein3.4.23.160.446
2r5q1UNGag-Pol polyprotein/0.445
3lzs017Gag-Pol polyprotein3.4.23.160.445
3qihFG7Gag-Pol polyprotein3.4.23.160.445
3tof076Gag-Pol polyprotein2.7.7.490.445
1hpv478Gag-Pol polyprotein/0.444
4j54G52Gag-Pol polyprotein3.4.23.160.444
1qbrXV6Gag-Pol polyprotein3.4.23.160.443
3toh079Gag-Pol polyprotein2.7.7.490.442
1qbt146Gag-Pol polyprotein3.4.23.160.441
2z4o065Gag-Pol polyprotein3.4.23.160.441
3aidARQGag-Pol polyprotein3.4.23.160.441
3bxrDRRGag-Pol polyprotein3.4.23.160.440
3ec0GRLGag-Pol polyprotein3.4.23.470.440