sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ei8	PL5	LL-diaminopimelate aminotransferase, chloroplastic

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3ei8	PL5	LL-diaminopimelate aminotransferase, chloroplastic	/	1.000
4ge7	0K5	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.490
4ge4	0KE	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.473
1x28	PGU	Aspartate aminotransferase	2.6.1.1	0.461
3fvu	IAC	Kynurenine--oxoglutarate transaminase 1	2.6.1.7	0.451
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.451
1arh	PPD	Aspartate aminotransferase	2.6.1.1	0.442