sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3eg5 | GNP | Cell division control protein 42 homolog |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 1.000 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.590 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.565 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.547 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.539 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.537 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.534 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.533 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.533 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.530 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.523 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.521 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.520 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.515 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.515 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.513 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.508 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.508 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.506 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.503 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.500 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.499 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.498 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.496 | |
| 4mit | GTP | Rho-related protein racC | / | 0.495 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.492 | |
| 4nyi | GNP | GTPase HRas | / | 0.492 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.491 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.490 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.489 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.489 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.489 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.488 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.488 | |
| 3oiv | GNP | GTPase HRas | / | 0.486 | |
| 3lbn | GNP | GTPase HRas | / | 0.485 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.484 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.484 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.483 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.482 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.481 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.480 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.479 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.479 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.478 | |
| 4nyj | GNP | GTPase HRas | / | 0.477 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.475 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.475 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.474 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.473 | |
| 3oiu | GNP | GTPase HRas | / | 0.473 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.472 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.472 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.472 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.472 | |
| 3i3s | GNP | GTPase HRas | / | 0.467 | |
| 3v4f | GNP | GTPase HRas | / | 0.465 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.458 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.457 | |
| 3rs5 | GNP | GTPase HRas | / | 0.455 | |
| 4dlt | GNP | GTPase HRas | / | 0.451 | |
| 5b2z | GNP | GTPase HRas | / | 0.450 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 3ddc | GNP | GTPase HRas | / | 0.449 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.447 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.447 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.446 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.445 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.443 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.440 |