scPDB - Distribution of Cavity Similarity values of 3eai entry / Site 2

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3eai	328	Nitric oxide synthase, inducible	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3eai	328	Nitric oxide synthase, inducible	1.14.13.39	1.000
3e68	AT6	Nitric oxide synthase, inducible	1.14.13.39	0.666
3ebf	332	Nitric oxide synthase, inducible	1.14.13.39	0.631
3e7m	AT2	Nitric oxide synthase, inducible	1.14.13.39	0.605
3e6t	1A2	Nitric oxide synthase, inducible	1.14.13.39	0.600
3e6o	A55	Nitric oxide synthase, inducible	1.14.13.39	0.596
3e7g	AT2	Nitric oxide synthase, inducible	1.14.13.39	0.585
1qw5	14W	Nitric oxide synthase, inducible	1.14.13.39	0.558
2y37	A54	Nitric oxide synthase, inducible	1.14.13.39	0.555
1vaf	ARR	Nitric oxide synthase, inducible	1.14.13.39	0.546
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.546
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.545
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.545
1zzu	DP1	Nitric oxide synthase, brain	1.14.13.39	0.544
1r35	I58	Nitric oxide synthase, inducible	1.14.13.39	0.543
3b3o	JI3	Nitric oxide synthase, brain	1.14.13.39	0.540
3e7i	B2	Nitric oxide synthase, inducible	1.14.13.39	0.537
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.534
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.529
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.526
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.523
1rs6	DP2	Nitric oxide synthase, brain	1.14.13.39	0.522
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.522
1zzr	DP9	Nitric oxide synthase, brain	1.14.13.39	0.520
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.520
3e7t	B14	Nitric oxide synthase, inducible	1.14.13.39	0.519
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.519
1m9t	INE	Nitric oxide synthase, inducible	1.14.13.39	0.518
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.517
3nlo	JSR	Nitric oxide synthase, brain	1.14.13.39	0.517
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.517
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.516
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.514
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.513
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.512
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.512
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.510
3jwu	J11	Nitric oxide synthase, brain	1.14.13.39	0.509
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.508
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.507
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.503
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.503
3nlk	JSS	Nitric oxide synthase, brain	1.14.13.39	0.503
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.503
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.502
4jsj	QJ7	Nitric oxide synthase, brain	1.14.13.39	0.502
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.501
4jsh	Q15	Nitric oxide synthase, brain	1.14.13.39	0.496
4fvz	4KJ	Nitric oxide synthase, brain	1.14.13.39	0.492
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.491
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.490
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.489
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.489
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.488
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.487
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.486
3e6t	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.485
4gqe	6KJ	Nitric oxide synthase, brain	1.14.13.39	0.485
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.484
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.483
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.483
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.482
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.482
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.481
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.481
3e6o	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.480
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.480
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.480
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.480
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.480
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.480
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.479
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.479
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.479
4fw0	5KJ	Nitric oxide synthase, brain	1.14.13.39	0.479
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.479
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.477
4jse	QJ2	Nitric oxide synthase, brain	1.14.13.39	0.477
1m8h	6NI	Nitric oxide synthase, inducible	1.14.13.39	0.476
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.476
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.474
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.474
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.474
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.473
3eah	327	Nitric oxide synthase, endothelial	1.14.13.39	0.472
3dqr	JI2	Nitric oxide synthase, brain	1.14.13.39	0.471
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.471
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.469
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.469
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.469
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.466
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.466
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.463
3ej8	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.462
4uga	Q05	Nitric oxide synthase oxygenase	1.14.13.165	0.460
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.457
1qw5	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.456
1r35	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.455
1qom	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.454
1m9j	CLW	Nitric oxide synthase, endothelial	1.14.13.39	0.450
1m9m	6NI	Nitric oxide synthase, endothelial	1.14.13.39	0.450
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.449
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.443
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.443
3e7i	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.442
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.440