scPDB - Distribution of Cavity Similarity values of 3e7g entry / Site 1

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3e7g	H4B	Nitric oxide synthase, inducible	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3e7g	H4B	Nitric oxide synthase, inducible	1.14.13.39	1.000
3e6o	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.569
2nod	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.543
3e6t	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.535
3n5z	H4B	Nitric oxide synthase, brain	1.14.13.39	0.524
4k5e	H4B	Nitric oxide synthase, brain	1.14.13.39	0.522
1r35	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.521
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.521
3dwj	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.519
3ej8	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.519
1qom	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.517
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.511
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.508
3nlo	H4B	Nitric oxide synthase, brain	1.14.13.39	0.506
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.504
1rs6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.503
1zzq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.502
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.501
1om5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.500
3b3o	H4B	Nitric oxide synthase, brain	1.14.13.39	0.499
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.499
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.499
1k2t	H4B	Nitric oxide synthase, brain	1.14.13.39	0.498
1p6j	H4B	Nitric oxide synthase, brain	1.14.13.39	0.498
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.498
3nw2	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.498
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.498
1k2u	H4B	Nitric oxide synthase, brain	1.14.13.39	0.497
1zzu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.497
5agl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.497
3b3p	H4B	Nitric oxide synthase, brain	1.14.13.39	0.496
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.496
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.496
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.496
3jwu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.495
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3nlk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
4k5d	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.491
3ufr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.491
3tym	H4B	Nitric oxide synthase, brain	1.14.13.39	0.490
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.490
2hx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.489
3b3n	H4B	Nitric oxide synthase, brain	1.14.13.39	0.489
4gqe	H4B	Nitric oxide synthase, brain	1.14.13.39	0.489
3nlw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.488
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.488
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.486
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.484
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.484
4imw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.484
3dqr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.483
3e67	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.481
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.481
3ufs	H4B	Nitric oxide synthase, brain	1.14.13.39	0.480
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.480
1zzr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.479
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.479
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.479
3jx2	H4B	Nitric oxide synthase, brain	1.14.13.39	0.478
3nlp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.476
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.476
4jse	H4B	Nitric oxide synthase, brain	1.14.13.39	0.476
3jwv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
3ufo	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
1rs7	H4B	Nitric oxide synthase, brain	1.14.13.39	0.474
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.474
3e7t	B14	Nitric oxide synthase, inducible	1.14.13.39	0.472
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
3ufp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
3ufw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
3nln	H4B	Nitric oxide synthase, brain	1.14.13.39	0.469
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
1m8e	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.466
3n5v	H4B	Nitric oxide synthase, brain	1.14.13.39	0.466
4k5f	H4B	Nitric oxide synthase, brain	1.14.13.39	0.465
3jx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.461
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.459
3jx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.457
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
3svq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3uft	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3rql	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
5agp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.450
2g6i	HBI	Nitric oxide synthase, brain	1.14.13.39	0.449
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.449
3jta	H4B	Nitric oxide synthase, brain	1.14.13.39	0.448
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.448
4jsh	H4B	Nitric oxide synthase, brain	1.14.13.39	0.448
3jt6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
1m9t	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.446
4fvy	H4B	Nitric oxide synthase, brain	1.14.13.39	0.446
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.445
1dwx	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.443
3jt8	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.443
3fc5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.442
5agk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
1vaf	H4B	Nitric oxide synthase, inducible	1.14.13.39	0.441
2g6j	7AP	Nitric oxide synthase, brain	1.14.13.39	0.440
3jt3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440
3jx6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440