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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/1.000
3e34ED1Protein farnesyltransferase subunit beta2.5.1.581.000
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.593
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.556
1s63778Protein farnesyltransferase subunit beta2.5.1.580.546
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.542
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.526
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.525
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.525
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.525
3q7fED2Uncharacterized protein/0.525
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.524
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.523
3sfy3FYUncharacterized protein/0.522
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.519
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.517
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.512
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.511
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.509
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.509
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.509
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.506
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.504
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.497
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.491