sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dhk | 23U | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 1.000 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.753 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.712 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.687 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.680 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.670 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.669 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.666 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.660 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.653 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.641 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.635 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.625 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.619 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.612 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.602 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.602 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.602 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.601 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.601 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.592 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.592 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.590 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.590 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.583 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.582 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.577 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.573 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.570 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.569 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.567 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.566 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.557 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.554 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.554 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.554 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.553 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.552 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.551 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.550 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.550 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.544 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.543 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.541 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.540 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.539 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.539 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.539 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.538 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.537 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.537 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.536 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.534 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.533 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.532 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.530 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.524 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.522 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.517 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.514 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.512 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.512 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.511 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.509 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.507 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.504 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.503 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.500 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.491 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.490 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.486 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.484 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.484 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.482 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.481 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.481 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.477 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.458 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.448 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.446 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.442 |