sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.758 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.740 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.610 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.599 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.584 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.583 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.574 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.563 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.560 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.553 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.546 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.536 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.535 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.527 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.521 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.518 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.510 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.507 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.501 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.499 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.498 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.498 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.497 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.496 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.488 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.487 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.486 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.484 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.484 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.483 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.482 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.478 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.476 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.473 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.472 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.472 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.472 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.472 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.470 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.469 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.469 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.469 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.468 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.467 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.467 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.467 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.465 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.465 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.464 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.463 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.462 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.461 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.460 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.460 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.460 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.459 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.459 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.458 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.458 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.458 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.458 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.458 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.458 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.457 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.456 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.456 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.456 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.456 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.454 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.454 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.453 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.453 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.453 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.453 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.452 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3pft | FMN | Flavin reductase | / | 0.452 | |
| 4jic | FMN | GTN Reductase | / | 0.452 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.451 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.451 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.451 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.451 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.451 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.451 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.451 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.450 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.450 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.450 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.450 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.450 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.450 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.450 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.449 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.449 | |
| 3eku | CY9 | Actin-5C | / | 0.449 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.449 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.448 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.448 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.448 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.448 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.448 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.448 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.448 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.448 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.447 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.447 | |
| 5cho | FAD | Flavin reductase | / | 0.447 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.446 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.445 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.445 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.445 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.445 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.444 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.444 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.444 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.444 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4nvk | 2NY | Peroxidase | / | 0.444 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.444 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.443 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.443 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.443 | |
| 4iah | 1DX | Alr2278 protein | / | 0.443 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.443 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.442 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.442 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.442 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.442 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.441 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.441 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.441 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.441 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.441 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.440 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.440 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.440 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.440 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.440 |