sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.857 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.827 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.814 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.812 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.802 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.800 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.793 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.784 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.777 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.774 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.773 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.767 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.749 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.745 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.730 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.621 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.586 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.575 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.571 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.554 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.554 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.552 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.543 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.535 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.533 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.529 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.527 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.514 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.512 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.508 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.499 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.488 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.487 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.481 | |
| 4iae | 1DX | Alr2278 protein | / | 0.478 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.472 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.466 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.463 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.463 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.462 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.462 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.460 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.459 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.459 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.458 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4nvk | 2NY | Peroxidase | / | 0.458 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.457 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.456 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.456 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.456 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.455 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.455 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.454 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4n1g | CEI | Obelin | / | 0.454 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.454 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 4boe | CLR | Japanin | / | 0.453 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.452 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.452 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.451 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.451 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.451 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.450 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.450 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.449 | |
| 4jic | FMN | GTN Reductase | / | 0.449 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.448 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1c7o | PPG | Hemolysin | / | 0.447 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.445 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.445 | |
| 3e8x | NAP | BH1520 protein | / | 0.445 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.445 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.445 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.444 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3ogk | OGK | Coronatine-insensitive protein 1 | / | 0.442 | |
| 3wag | TYD | Glycosyltransferase | / | 0.442 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.442 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.440 |