sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3d77 | NBB | Pheromone-binding protein ASP1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 1.000 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.618 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.588 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.568 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.563 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.545 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.508 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.501 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.500 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.495 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.494 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.487 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.486 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.482 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.478 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.477 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.476 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.473 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.472 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.471 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.470 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.469 | |
| 3wxy | COA | Uncharacterized protein | / | 0.469 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.468 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.468 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.468 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.467 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.467 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.466 | |
| 1r2j | FAD | FkbI | / | 0.466 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.466 | |
| 4l8u | 9AZ | Serum albumin | / | 0.466 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.466 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.466 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.465 | |
| 3aba | FLI | Cytochrome P450 | / | 0.465 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.465 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.464 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.464 | |
| 2pnu | ENM | Androgen receptor | / | 0.463 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.462 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.462 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2qjp | ANJ | Cytochrome b | / | 0.461 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.461 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.461 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.461 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.461 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 3ogq | AB1 | Pol polyprotein | / | 0.460 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.460 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.459 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.458 | |
| 4b1f | KRH | Glutamate racemase | / | 0.458 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.457 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.457 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.457 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.457 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.456 | |
| 4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.456 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.456 | |
| 1kyo | SMA | Cytochrome b | / | 0.455 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.455 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.454 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.454 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.454 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.453 | |
| 2wpx | ACO | Orf14 | / | 0.453 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.453 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.452 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.452 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.452 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.452 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.452 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.452 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.451 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.451 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.451 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.451 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.451 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.451 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.450 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.450 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.450 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.450 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.450 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.449 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.449 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.449 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.449 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.449 | |
| 3qly | 55V | Uncharacterized protein | / | 0.449 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.449 | |
| 3ufu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 1jld | 0PP | Gag-Pol polyprotein | / | 0.448 | |
| 1sqb | AZO | Cytochrome b | / | 0.448 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.448 | |
| 2wpw | ACO | Orf14 | / | 0.448 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.448 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.448 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.448 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.447 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3cx5 | SMA | Cytochrome b | / | 0.447 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.447 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.447 | |
| 4boe | CLR | Japanin | / | 0.447 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4xsr | UPG | Alr3699 protein | / | 0.447 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.446 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.446 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.446 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 2yiu | SMA | Cytochrome b | / | 0.446 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.446 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.446 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.446 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.446 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1kk4 | ACO | Streptogramin A acetyltransferase | 2.3.1 | 0.445 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.445 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2bxa | C1F | Serum albumin | / | 0.445 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2pog | WST | Estrogen receptor | / | 0.445 | |
| 2qjy | SMA | Cytochrome b | / | 0.445 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.445 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4nqg | CZH | Mitrocomin | / | 0.445 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ppj | ANY | Cytochrome b | / | 0.444 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.444 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.444 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.444 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.444 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4iae | 1DX | Alr2278 protein | / | 0.444 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.444 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.443 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.443 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.443 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.443 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.443 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.443 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.443 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.443 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.443 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.443 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.443 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.443 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.442 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.442 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 2za0 | MGI | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.441 | |
| 3up0 | D7S | aceDAF-12 | / | 0.441 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.441 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 4zas | TYD | CalS13 | / | 0.441 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 1tg5 | 645 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.440 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.440 | |
| 2acw | UPG | Glycosyltransferase | / | 0.440 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3n8x | NIM | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.440 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3saz | 043 | Malate synthase G | / | 0.440 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 4iah | 1DX | Alr2278 protein | / | 0.440 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.440 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.440 |