sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3cx6	GDP	Guanine nucleotide-binding protein subunit alpha-13

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3cx6	GDP	Guanine nucleotide-binding protein subunit alpha-13	/	1.000
3cx8	GSP	Guanine nucleotide-binding protein subunit alpha-13	/	0.509
1zcb	GDP	Guanine nucleotide-binding protein subunit alpha-13	/	0.472
1cul	GSP	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	/	0.471
1cs4	GSP	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	/	0.456
4fid	GDP	G protein alpha subunit, putative	/	0.454
4e07	ACP	Plasmid partitioning protein ParF	/	0.451
3c16	GSP	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	/	0.442