Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3cwq | ADP | ParA family chromosome partitioning protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 1.000 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.526 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.526 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.506 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.504 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.502 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.502 | |
| 4l4x | NDP | AmphI | / | 0.501 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.500 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.500 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.499 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.498 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.497 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.497 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.496 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.496 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.496 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.494 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.494 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.493 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.493 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.492 | |
| 3wag | TYD | Glycosyltransferase | / | 0.492 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.491 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.491 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.491 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.489 | |
| 4jic | FMN | GTN Reductase | / | 0.489 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.488 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.488 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.488 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.488 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.487 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.487 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.487 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.487 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.487 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.486 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.486 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.486 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.484 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.484 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.484 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.484 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.484 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.484 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.484 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.483 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.483 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.482 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.482 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.482 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.481 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.481 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.481 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.480 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.480 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.480 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.480 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.480 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.480 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.480 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.480 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.480 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.480 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.480 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.480 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.480 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.479 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.479 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.479 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.479 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.479 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.479 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.479 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.479 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.479 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.479 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.478 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.478 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.478 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.478 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.478 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.478 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.477 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.477 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4hxy | NDP | Plm1 | / | 0.477 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.477 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.476 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.476 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.476 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.476 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.476 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.476 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.476 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.476 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.476 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.476 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.476 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.476 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.475 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.475 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.475 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.475 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.475 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.475 | |
| 4irn | FAD | AnaB | / | 0.475 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.474 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.474 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.474 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.474 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.474 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.474 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.474 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.474 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.474 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.473 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.473 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.473 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.473 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.473 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.473 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.473 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.473 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.472 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.472 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.472 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.472 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.472 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.472 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.472 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.471 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.471 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.471 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.470 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.470 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.470 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.470 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.470 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.470 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.469 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.469 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.469 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.469 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.469 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.469 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.469 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.469 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.469 | |
| 5a3b | APR | SIR2 family protein | / | 0.469 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.468 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.468 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.468 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.468 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.468 | |
| 4yry | NAD | Glutamate synthase, beta subunit | / | 0.468 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.467 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.467 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.467 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.467 | |
| 3akd | CDP | Cytidylate kinase | / | 0.467 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.467 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.466 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.466 | |
| 1tys | TMP | Thymidylate synthase | / | 0.466 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.466 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.466 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.466 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.465 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.465 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.465 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.465 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.465 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.465 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.465 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.465 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.465 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.465 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.465 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.465 | |
| 5c41 | ACP | Ribokinase | / | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.464 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.464 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.464 | |
| 3ieu | GDP | GTPase Era | / | 0.464 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.464 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.464 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.464 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.464 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.464 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.463 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.463 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.463 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.463 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.463 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.463 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.463 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.463 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.463 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.463 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.462 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.462 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.462 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.462 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.462 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.462 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.462 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.462 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.462 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.462 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 3a37 | ADP | ATPase GET3 | / | 0.462 | |
| 3bnk | FMN | Flavoredoxin | / | 0.462 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.462 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.462 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.462 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3v2u | ATP | Protein GAL3 | / | 0.462 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.462 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.462 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.462 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.462 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.462 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.462 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.461 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.461 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.461 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.461 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.461 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.461 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.461 | |
| 3a3g | DLZ | Lumazine protein | / | 0.461 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.461 | |
| 3lbe | COA | Uncharacterized protein | / | 0.461 | |
| 3mje | NDP | AmphB | / | 0.461 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.461 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.461 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.461 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.461 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.461 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.461 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.460 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.460 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.460 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.460 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.460 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.460 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.460 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.460 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.460 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3gtc | GTC | Beta-lactamase | 3.5.2.6 | 0.460 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.460 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.460 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.459 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.459 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.459 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.459 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.459 | |
| 3ftx | RE2 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.459 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.459 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.459 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.459 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.459 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.459 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.459 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.459 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1vbm | YSA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.458 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.458 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.458 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.458 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.458 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.458 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.458 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.458 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.458 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.457 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.457 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.457 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.457 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.457 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.457 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.457 | |
| 4e2d | FMN | Dehydrogenase | / | 0.457 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.457 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.457 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.456 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.456 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.456 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 2uyi | ADP | Kinesin-like protein KIF11 | / | 0.456 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.456 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.456 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.456 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.456 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.456 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 4blr | UTP | NTPase P4 | / | 0.456 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.456 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.456 | |
| 4kwh | NAP | Reductase homolog | / | 0.456 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.455 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.455 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.455 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.455 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.455 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.455 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.455 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.455 | |
| 1zdw | FLV | Prenyltransferase | / | 0.455 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.455 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.455 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.455 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 3iaa | TYD | CalG2 | / | 0.455 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.455 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.455 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.455 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.454 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.454 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.454 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.454 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.454 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.454 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.454 | |
| 3u9e | COA | Lmo1369 protein | / | 0.454 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.454 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.454 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.454 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.454 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.454 | |
| 5a3c | NAD | SIR2 family protein | / | 0.454 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.453 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.453 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.453 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.453 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.453 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.453 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.453 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.453 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.453 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.453 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.453 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.453 | |
| 4yak | ACO | Acyl-CoA synthetase (NDP forming) | / | 0.453 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.452 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.452 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.452 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.452 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.452 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.452 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.452 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.452 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.452 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.452 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.452 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.452 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.452 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.452 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.452 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.451 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.451 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.451 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.451 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.451 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.451 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.451 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.451 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.451 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.451 | |
| 3uq9 | TBN | Putative adenosine kinase | / | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4ju9 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.451 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.451 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.451 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.451 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.451 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.451 | |
| 1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.450 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.450 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.450 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.450 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.450 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.450 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.450 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.450 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.450 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.450 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.450 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.450 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.450 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.450 | |
| 4v12 | POG | MaoC like domain protein | / | 0.450 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 5c4n | NAP | Precorrin-6A reductase | 1.3.1.54 | 0.450 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.449 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.449 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.449 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.449 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.449 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.449 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.449 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.449 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.449 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.449 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.449 | |
| 2zrj | AGS | Protein RecA | / | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 3gob | HXX | DdmC | / | 0.449 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.449 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.449 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.449 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.449 | |
| 4qbf | AP5 | Adenylate kinase | / | 0.449 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.449 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.449 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.449 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.448 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.448 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.448 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.448 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.448 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.448 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2r8p | T6F | Transketolase 1 | / | 0.448 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.448 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.448 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.448 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.448 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.448 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.448 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.448 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.448 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.448 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.447 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.447 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.447 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.447 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.447 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.447 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.447 | |
| 2r8o | T5X | Transketolase 1 | / | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.447 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.447 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.447 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.447 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.447 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.447 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.446 | |
| 1kap | GLY_SER_ASN_SER | Serralysin | 3.4.24.40 | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.446 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.446 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.446 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.446 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.446 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.446 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3hf3 | FMN | Chromate reductase | / | 0.446 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.446 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.446 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.446 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.446 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4e2b | FMN | Dehydrogenase | / | 0.446 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.446 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.446 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 5ftf | ADP | TPR domain protein | / | 0.446 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.445 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.445 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.445 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.445 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.445 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.445 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.445 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.445 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.445 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3m2t | NAD | Probable dehydrogenase | / | 0.445 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.445 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.445 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.445 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.445 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.445 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.445 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.445 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 5ccy | TMP | Polymerase acidic protein | / | 0.445 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.444 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.444 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.444 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.444 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.444 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.444 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2dsg | SAH | Diphthine synthase | / | 0.444 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.444 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 2r9v | ATP | ATP synthase subunit alpha | / | 0.444 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.444 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.444 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.444 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.444 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.444 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.444 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.444 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.444 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.444 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.443 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.443 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.443 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.443 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.443 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1tys | DHF | Thymidylate synthase | / | 0.443 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.443 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.443 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.443 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.443 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.443 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.443 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3vaq | ADN | Putative adenosine kinase | / | 0.443 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.443 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.443 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1c7o | PPG | Hemolysin | / | 0.442 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.442 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.442 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.442 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.442 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.442 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.442 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.442 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.442 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.442 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.442 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.442 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.442 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.442 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.442 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.442 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.441 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.441 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.441 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.441 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.441 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.441 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.441 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.441 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.441 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.441 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.441 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.441 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.441 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.441 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.441 | |
| 3ovs | CTP | CCA-adding enzyme | 2.7.7.72 | 0.441 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.441 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.441 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4xr9 | NAD | CalS8 | / | 0.441 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.441 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1glb | ADP | Glycerol kinase | / | 0.440 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.440 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.440 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.440 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.440 | |
| 1uay | ADN | Oxidoreductase | / | 0.440 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.440 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.440 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.440 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.440 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.440 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.440 | |
| 3uce | NDP | Dehydrogenase | / | 0.440 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.440 | |
| 3w8r | ACP | Uridine kinase | / | 0.440 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4a30 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.440 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.440 |