sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3cv7	C2U	Alcohol dehydrogenase [NADP(+)]	1.1.1.2

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3cv7	C2U	Alcohol dehydrogenase [NADP(+)]	1.1.1.2	1.000
3fx4	FX4	Alcohol dehydrogenase [NADP(+)]	1.1.1.2	0.585
1az1	ALR	Aldose reductase	1.1.1.21	0.475
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.455
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.455
1pq9	44B	Oxysterols receptor LXR-beta	/	0.454
3zku	HCV	Isopenicillin N synthase	1.21.3.1	0.443
2bxo	OPB	Serum albumin	/	0.442
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.442
3hxb	BD5	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.442
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.441
4c77	N01	Phenylacetone monooxygenase	1.14.13.92	0.441
2bu9	HFV	Isopenicillin N synthase	1.21.3.1	0.440