scPDB - Distribution of Cavity Similarity values of 3cse entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3cse	N22	Uncharacterized protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3cse	N22	Uncharacterized protein	/	1.000
3eek	53S	Uncharacterized protein	/	0.720
3qlz	QLZ	Uncharacterized protein	/	0.667
4h98	14Q	Uncharacterized protein	/	0.665
3eel	53T	Uncharacterized protein	/	0.606
3qlx	QLR	Uncharacterized protein	/	0.602
3qgt	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.586
1cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.575
3eej	53R	Uncharacterized protein	/	0.574
3eem	53V	Uncharacterized protein	/	0.574
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.572
2bl9	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.570
3um6	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.569
2fzi	DH3	Dihydrofolate reductase	1.5.1.3	0.558
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.554
3qly	55V	Uncharacterized protein	/	0.551
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.549
1m78	CLZ	Dihydrofolate reductase	1.5.1.3	0.548
2blc	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.547
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.544
4dp3	MMV	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.540
3um5	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.539
3kjs	DQ1	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.535
2cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.534
3inv	C50	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.533
3qg2	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.533
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.527
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.522
1j3j	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.521
3jsu	KA5	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.518
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.517
4dph	P65	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.511
3qfx	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.507
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.507
3cd2	MTX	Dihydrofolate reductase	1.5.1.3	0.504
3clb	TMQ	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.504
1aoe	GW3	Dihydrofolate reductase	1.5.1.3	0.503
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.503
1j3k	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.502
3qlr	QLR	Dihydrofolate reductase	1.5.1.3	0.502
3dga	RJ1	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.500
1klk	PMD	Dihydrofolate reductase	1.5.1.3	0.499
1rx3	MTX	Dihydrofolate reductase	1.5.1.3	0.499
3irn	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.499
4fgg	0U5	Dihydrofolate reductase	1.5.1.3	0.499
2blb	CP7	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.498
3qls	55V	Dihydrofolate reductase	1.5.1.3	0.496
3dg8	RJ6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.495
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.495
1m7a	MQU	Dihydrofolate reductase	1.5.1.3	0.494
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	0.494
4xe6	06U	Dihydrofolate reductase	1.5.1.3	0.494
1daj	MOT	Dihydrofolate reductase	1.5.1.3	0.493
4h97	53S	Dihydrofolate reductase	1.5.1.3	0.493
3qlw	N22	Dihydrofolate reductase	1.5.1.3	0.492
1dg5	TOP	Dihydrofolate reductase	1.5.1.3	0.488
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.488
3dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.487
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.487
1ia1	TQ3	Dihydrofolate reductase	1.5.1.3	0.485
1ly3	COG	Dihydrofolate reductase	1.5.1.3	0.485
1s3y	TQT	Dihydrofolate reductase	1.5.1.3	0.485
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.485
3um8	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.483
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.481
1e26	GPB	Dihydrofolate reductase	1.5.1.3	0.477
3dga	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.477
2w3v	TOP	Dihydrofolate reductase	/	0.476
4ixf	IXF	Dihydrofolate reductase	1.5.1.3	0.475
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.474
1ly4	COQ	Dihydrofolate reductase	1.5.1.3	0.474
3inv	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.474
3ia4	MTX	Dihydrofolate reductase	/	0.473
3jwc	EKB	Dihydrofolate reductase	/	0.473
3iro	2CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.472
3jwm	5WB	Dihydrofolate reductase	/	0.472
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.469
1dg7	WRB	Dihydrofolate reductase	1.5.1.3	0.468
3fre	TOP	Dihydrofolate reductase	1.5.1.3	0.466
3sa2	7DR	Dihydrofolate reductase	/	0.465
3sa1	6DR	Dihydrofolate reductase	/	0.463
3kjs	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.460
4g8z	TOP	Dihydrofolate reductase	1.5.1.3	0.460
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.459
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.459
2bla	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.457
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.457
2zza	FOL	Dihydrofolate reductase	/	0.454
1m13	HYF	Nuclear receptor subfamily 1 group I member 2	/	0.452
3srq	Q19	Dihydrofolate reductase	1.5.1.3	0.452
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.452
1ia2	TQ4	Dihydrofolate reductase	1.5.1.3	0.451
3qls	NDP	Dihydrofolate reductase	1.5.1.3	0.451
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.450
1df7	MTX	Dihydrofolate reductase	1.5.1.3	0.449
1og5	SWF	Cytochrome P450 2C9	/	0.449
4ixg	IXG	Dihydrofolate reductase	1.5.1.3	0.449
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.448
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.447
1qkn	RAL	Estrogen receptor beta	/	0.447
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.447
3dg8	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.446
1dg8	NDP	Dihydrofolate reductase	1.5.1.3	0.445
1s3w	TQT	Dihydrofolate reductase	1.5.1.3	0.445
3rg9	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.444
4ele	31I	Dihydrofolate reductase	/	0.444
3sai	9DR	Dihydrofolate reductase	/	0.442
3fwf	CAM	Camphor 5-monooxygenase	1.14.15.1	0.441
3nxo	D2B	Dihydrofolate reductase	1.5.1.3	0.441
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.441
1kzj	CB3	Thymidylate synthase	/	0.440
3frd	DHF	Dihydrofolate reductase	1.5.1.3	0.440
4ejh	0QA	Cytochrome P450 2A13	1.14.14.1	0.440