sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3ch6	311	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3ch6	311	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	1.000
4hfr	14M	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.538
3fco	IIG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.537
4hx5	19V	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.512
3czr	3CZ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.502
3bzu	A21	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.494
3gmd	2M3	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.492
4bb6	HD1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.486
3ey4	352	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.475
3oq1	3OQ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.473
3d3e	D3E	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.468
1xu7	CPS	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.467
1y5r	C0R	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.462
4bb5	HD2	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.462
3tfq	07M	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.459
2rbe	ZMG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.457