sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 1.000 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.625 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.619 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.593 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.583 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.568 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.529 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.525 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.472 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.463 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.459 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.454 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.448 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.445 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.445 | |
| 4wbn | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.440 |