Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3c27 | DKK | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 1.000 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.718 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.718 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.710 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.710 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.692 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.689 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.682 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.680 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.675 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.668 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.668 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.663 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.655 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.651 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.651 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.646 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.644 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.643 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.643 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.641 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.635 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.633 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.629 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.629 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.629 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.628 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.623 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.622 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.621 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.621 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.617 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.617 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.616 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.613 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.611 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.610 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.610 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.610 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.609 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.606 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.606 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.601 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.599 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.598 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.598 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.597 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.595 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.593 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.591 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.590 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.589 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.587 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.587 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.584 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.582 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.580 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.579 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.578 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.576 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.576 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.575 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.575 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.575 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.575 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.575 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.574 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.572 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.571 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.570 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.569 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.568 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.568 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.566 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.565 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.564 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.563 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.561 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.560 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.560 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.558 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.552 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.548 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.543 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.540 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.537 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.536 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.535 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.534 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.533 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.529 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.526 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.525 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.518 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.516 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.513 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.511 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.509 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.509 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.507 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.506 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.502 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.501 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.500 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.500 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.500 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.499 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.499 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.496 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.494 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.494 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.492 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.492 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.492 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.492 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.491 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.490 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.489 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.489 | |
| 4h6p | FMN | Chromate reductase | / | 0.489 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.488 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.486 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.486 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.485 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.485 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.484 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.483 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.483 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.481 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.480 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.479 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.479 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.477 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.477 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.477 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.477 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.477 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.476 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.476 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.476 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.476 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.476 | |
| 3v2u | ATP | Protein GAL3 | / | 0.476 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.475 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.474 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.474 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.474 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.474 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.473 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.473 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.473 | |
| 3c1o | NAP | Eugenol synthase | / | 0.473 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.473 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.472 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.472 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.472 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.472 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.472 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.472 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.472 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.471 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.471 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.471 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.471 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.471 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.471 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.470 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.470 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.469 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.469 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.469 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.469 | |
| 3eks | CY9 | Actin-5C | / | 0.469 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.469 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.468 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.468 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.468 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 3r96 | ACO | MccE protein | / | 0.468 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.467 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.467 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.467 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.467 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.467 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.467 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.467 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.466 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.466 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.466 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.466 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.466 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.466 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.465 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 2ejk | SAH | Diphthine synthase | / | 0.465 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3rim | TPP | Transketolase | 2.2.1.1 | 0.465 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.465 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.464 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.464 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.464 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.464 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.464 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.463 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.463 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.463 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.463 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.463 | |
| 1r2j | FAD | FkbI | / | 0.463 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.463 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.463 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3s7b | NH5 | N-lysine methyltransferase SMYD2 | / | 0.463 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.463 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.463 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.463 | |
| 1o1t | 2NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.462 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.462 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.462 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.462 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.462 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.462 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.461 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.461 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.461 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.461 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.461 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.461 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.461 | |
| 1c7o | PPG | Hemolysin | / | 0.460 | |
| 1lke | DOG | Bilin-binding protein | / | 0.460 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.460 | |
| 2r8o | T5X | Transketolase 1 | / | 0.460 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.460 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.460 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.460 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.460 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.460 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.460 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.460 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.459 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.459 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.459 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 2r5n | TPP | Transketolase 1 | / | 0.459 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.459 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.459 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3ihz | FK5 | Peptidylprolyl isomerase | / | 0.459 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.459 | |
| 3sju | NDP | Keto reductase | / | 0.459 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.459 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.459 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.459 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.458 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.458 | |
| 2ejz | SAH | Diphthine synthase | / | 0.458 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.458 | |
| 2r8p | T6F | Transketolase 1 | / | 0.458 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.458 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.458 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4e2b | FMN | Dehydrogenase | / | 0.458 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.458 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.457 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.457 | |
| 2o12 | FMN | Chorismate synthase | / | 0.457 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.457 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.457 | |
| 4nvk | 2NY | Peroxidase | / | 0.457 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 1ppj | ANY | Cytochrome b | / | 0.456 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.456 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.456 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.456 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.456 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.456 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.456 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.455 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.455 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.455 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.455 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.455 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.455 | |
| 4e32 | DWN | Methyltransferase | / | 0.455 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.454 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.454 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.454 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.454 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.454 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.454 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.454 | |
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.454 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.454 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.454 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.453 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.453 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.453 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.453 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.453 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.453 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4jxr | ACO | Acetyltransferase | / | 0.453 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.453 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.452 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.452 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.452 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.452 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.452 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.452 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.452 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.452 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.452 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.452 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.452 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.452 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.451 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.451 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.451 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.451 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 4e2x | TYD | Methyltransferase | / | 0.451 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.451 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4j7g | TRH | PCZA361.3 | / | 0.451 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.451 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.451 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.450 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.450 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.450 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.450 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.450 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.450 | |
| 3nt5 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.450 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.450 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.450 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.450 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.450 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.449 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.449 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3qvi | K95 | HAP protein | / | 0.449 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4kwc | SAH | Methyltransferase domain family | / | 0.449 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 4yfy | 0FX | VioF | / | 0.449 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.449 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.448 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3eq6 | BCO | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.448 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.448 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.448 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.448 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.448 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.448 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.448 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1e6z | NGO | Chitinase | / | 0.447 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.447 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.447 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.447 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.447 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.447 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.447 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.447 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.447 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.446 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.446 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 | 0.446 | |
| 1xa4 | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.446 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.446 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.446 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.446 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.446 | |
| 3frk | TQP | QdtB | / | 0.446 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3klb | FMN | Uncharacterized protein | / | 0.446 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.446 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.446 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.446 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.446 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.446 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.445 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.445 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.445 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.445 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.445 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.445 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.445 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.445 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.445 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.445 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.445 | |
| 3h5u | H5U | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3iaa | TYD | CalG2 | / | 0.445 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.445 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.445 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.445 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.445 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.445 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.445 | |
| 5jjr | SAH | Genome polyprotein | / | 0.445 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.444 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.444 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.444 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.444 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.444 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.444 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.444 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.444 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.444 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.444 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.444 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.443 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.443 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.443 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.443 | |
| 2avi | BTN | Avidin | / | 0.443 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.443 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.443 | |
| 3awh | FMN | FMN-binding protein | / | 0.443 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.443 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.443 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.443 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.443 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.443 | |
| 3wzn | BTN | Streptavidin | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.443 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.443 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.442 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.442 | |
| 2po3 | T4K | 4-dehydrase | / | 0.442 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.442 | |
| 2uyw | BTN | Avd protein | / | 0.442 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.442 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.442 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.442 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.442 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4kbz | 1QA | Egl nine homolog 1 | / | 0.442 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.442 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.442 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.442 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1vce | SAH | Diphthine synthase | / | 0.441 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.441 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.441 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.441 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.441 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.441 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.441 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.441 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.441 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.440 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.440 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.440 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.440 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2x90 | EAL | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.440 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.440 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.440 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.440 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4l96 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4lut | DCS | Alanine racemase | / | 0.440 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.440 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.440 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.440 |