sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3c1k | T15 | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 1.000 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.710 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.691 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.657 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.650 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.648 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.648 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.634 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.628 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.626 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.622 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.613 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.609 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.608 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.606 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.602 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.601 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.596 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.591 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.588 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.586 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.585 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.582 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.580 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.579 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.579 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.578 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.576 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.575 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.575 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.574 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.574 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.573 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.573 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.573 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.571 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.565 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.564 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.563 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.560 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.560 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.558 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.557 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.556 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.555 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.552 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.552 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.548 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.541 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.541 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.539 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.536 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.533 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.532 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.532 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.529 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.525 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.523 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.523 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.521 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.519 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.516 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.515 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.514 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.514 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.512 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.497 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.496 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.493 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.493 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.492 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.492 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.489 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.487 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.483 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.482 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.482 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.480 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.479 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.479 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.476 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.475 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.474 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.474 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.468 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.463 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.459 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.456 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.456 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.456 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.452 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.446 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.446 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.442 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.440 |