Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.11.000
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.469
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.463
2zjwREFCasein kinase II subunit alpha2.7.11.10.453
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.451
4ez50RSCyclin-dependent kinase 62.7.11.220.441